Compile Data Set for Download or QSAR
maximum 50k data
Found 5 of ec50 data for polymerid = 194,6551
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)
Affinity DataEC50:  22nMAssay Description:cAMP elevation in U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataEC50:  1.10E+3nMAssay Description:cAMP elevation in U937 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310217(7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphenyl)...)
Affinity DataEC50:  1.61E+3nMAssay Description:Inhibition of human PDE4D in U937 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50516235(CHEMBL4563408)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human recombinant PDE4D2 using [3H]cAMP as substrate measured after 20 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310204(7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphenyl)...)
Affinity DataEC50:  6.69E+4nMAssay Description:Inhibition of human PDE4D in U937 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed