Affinity DataEC50: 0.0930nMAssay Description:Displacement of [125I]CCK-8 from CCK2 receptor in human FGS7 Jurkat cellsMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 0.170nMAssay Description:Agonist activity at gastrin receptor in rat AR4-2J cells assessed as intracellular calcium mobilization by fluorescence assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 0.270nMAssay Description:Agonist activity at gastrin receptor in rat AR4-2J cells assessed as intracellular calcium mobilization by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.295nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.316nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.324nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 0.330nMAssay Description:Agonist activity at gastrin receptor in rat AR4-2J cells assessed as intracellular calcium mobilization by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.331nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.380nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.380nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 0.400nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
Affinity DataEC50: 0.407nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 0.410nMAssay Description:Agonist activity at gastrin receptor in rat AR4-2J cells assessed as intracellular calcium mobilization by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.417nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.417nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 0.430nMAssay Description:Agonist activity at rat CCK2R expressed in rat AR42J cells assessed as intracellular calcium mobilization measured after 24 hrs by Fluo-4AM dye based...More data for this Ligand-Target Pair
Affinity DataEC50: 0.437nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.437nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.447nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.457nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.457nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.501nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.501nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 0.560nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 0.630nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 0.630nMAssay Description:Effective concentration for the stimulation of Inositol Phosphate accumulation in CHO cells expressing wild-type Cholecystokinin type B receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.631nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.832nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 1.30nMAssay Description:Agonist activity at rat CCK2R expressed in rat AR42J cells assessed as intracellular calcium mobilization measured after 24 hrs by Fluo-4AM dye based...More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 1.40nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Inhibition of (Thr,Nle)-CCK-9 -induced inositol phosphate production in COS-7 cells expressing human CCK2 receptorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Effective concentration for the stimulation of Inositol Phosphate accumulation in CHO cells expressing wild-type Cholecystokinin type B receptorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 1.64nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 1.70nMAssay Description:Agonist activity at rat CCK2R expressed in rat AR42J cells assessed as intracellular calcium mobilization measured after 24 hrs by Fluo-4AM dye based...More data for this Ligand-Target Pair
Affinity DataEC50: 1.90nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 1.90nMAssay Description:Agonist activity at rat CCK2R expressed in rat AR42J cells assessed as intracellular calcium mobilization measured after 24 hrs by Fluo-4AM dye based...More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 2nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
Affinity DataEC50: 2.40nMAssay Description:Agonist activity at human CCK2R expressed in HEK293 cells assessed as ERK1/2 phosphorylation incubated for 5 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.66nMAssay Description:Activity at CCK2R-MOPR (unknown origin) coexpressed in CHO cells cotransfected with delta6-Galphaqi4-myr assessed as intracellular calcium release by...More data for this Ligand-Target Pair
Affinity DataEC50: 2.70nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nM EC50: 2.80nMAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
Affinity DataEC50: 2.80nMAssay Description:Agonist activity at human CCK2R expressed in human A431 cells assessed as intracellular calcium mobilization measured after 24 hrs by Fluo-4AM dye ba...More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 3.30nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 3.40nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(RAT)
University Medical Centre Ljubljana
Curated by ChEMBL
University Medical Centre Ljubljana
Curated by ChEMBL
Affinity DataEC50: 4nMAssay Description:Effective concentration for the stimulation of Inositol Phosphate accumulation in CHO cells expressing wild-type Cholecystokinin type B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nM EC50: 4.60nMAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair