Compile Data Set for Download or QSAR
maximum 50k data
Found 24 of ec50 data for polymerid = 50001237,50006966
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50465773(CHEMBL4277250)
Affinity DataEC50:  20nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50526876(CHEMBL4457044)
Affinity DataEC50:  80nMAssay Description:Activation of human Kv7.4 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50592357(CHEMBL5185685)
Affinity DataEC50:  87nMAssay Description:Agonist activity at Kv7.4 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50526877(CHEMBL4545892)
Affinity DataEC50:  100nMAssay Description:Activation of human Kv7.4 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50465774(CHEMBL4287894)
Affinity DataEC50:  100nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50465777(CHEMBL4288707)
Affinity DataEC50:  160nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50592355(CHEMBL5200636)
Affinity DataEC50:  320nMAssay Description:Agonist activity at Kv7.4 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50121051(CHEMBL3621437)
Affinity DataEC50:  376nMAssay Description:Activation of rat Kv7.4 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50121051(CHEMBL3621437)
Affinity DataEC50:  625nMAssay Description:Activation of human Kv7.4 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50592360(CHEMBL4549229)
Affinity DataEC50:  660nMAssay Description:Agonist activity at Kv7.4 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50521289(CHEMBL4588394)
Affinity DataEC50:  780nMAssay Description:Agonist activity at human KCNQ4 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50521287(CHEMBL4448132)
Affinity DataEC50:  890nMAssay Description:Activation of human homomeric KCNQ4 expressed in CHOK1 cells at -10 mV by whole cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50592356(CHEMBL4458793)
Affinity DataEC50:  910nMAssay Description:Agonist activity at Kv7.4 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50521288(CHEMBL4438770)
Affinity DataEC50:  1.42E+3nMAssay Description:Agonist activity at human KCNQ4 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50465775(CHEMBL1703636)
Affinity DataEC50:  1.60E+3nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143558(CHEMBL41355 | EZOGABINE | N-(2-amino-4-(4-fluorobe...)
Affinity DataEC50:  1.98E+3nMAssay Description:Activation of human Kv7.4 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50521286(CHEMBL4450214)
Affinity DataEC50:  2.03E+3nMAssay Description:Agonist activity at human KCNQ4 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50426567(BMS-204352 | FLINDOKALNER | MaxiPost)
Affinity DataEC50:  2.40E+3nMAssay Description:Positive modulatory activity at voltage-gated K channel 7.4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50465778(CHEMBL4287478)
Affinity DataEC50:  4.00E+3nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143558(CHEMBL41355 | EZOGABINE | N-(2-amino-4-(4-fluorobe...)
Affinity DataEC50:  5.90E+3nMAssay Description:Agonist activity at human KCNQ4 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50594442(CHEMBL5178988)
Affinity DataEC50:  6.40E+3nMAssay Description:Agonist activity at human KCNQ4 channel expressed in CHO cells assessed as increase in outward current by patch clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50465779(CHEMBL4278049)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50420049(CHEMBL402146)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50390916(CHEMBL2070953)
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of KCNQ4 channel expressed in CHO cells assessed as depolarization-induced thallium influx after 3 mins by patch clamp assay relative to c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed