Found 70 of ec50 data for polymerid = 50006469,6691 
Affinity DataEC50: 2nMAssay Description:Inverse agonist activity at RORgammat in mouse Th17 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.70nMAssay Description:Inverse agonist activity at RORgammat in mouse Th17 cells assessed as inhibition of CD3/CD28/IL-1/IL-23-induced IL-17A production measured after 24 h...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 9nMAssay Description:Activity at RoRc in mouse CD4+ T cells assessed as inhibition of IL-17 productionMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Inverse agonist activity at RORgammat in mouse Th17 cells assessed as inhibition of CD3/CD28/IL-1/IL-23-induced IL-17A production measured after 24 h...More data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Inverse agonist activity at RORgammat in mouse whole blood assessed as suppression of Th17 secretionMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Inverse agonist activity at RORgammat in mouse cells by mTh17 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 29nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Agonist activity at RORgammat in C57/B6 mouse Th17 cells assessed as increase in IL17A expression after 96 hrs by AlphaLISAMore data for this Ligand-Target Pair
Affinity DataEC50: 33nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 34nMAssay Description:Agonist activity at RORgammat in C57/B6 mouse Th17 cells assessed as increase in IL17A expression after 96 hrs by AlphaLISAMore data for this Ligand-Target Pair
Affinity DataEC50: 34nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
Affinity DataEC50: 37nMAssay Description:Agonist activity at RORgammat in mouse CD4+ T cells assessed as induction of Th17 cells differentiation by measuring increase in IL17 production meas...More data for this Ligand-Target Pair
Affinity DataEC50: 38nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
Affinity DataEC50: 38nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 43nMAssay Description:Inverse agonist activity at RORgammat in mouse Th17 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 53nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
Affinity DataEC50: 54nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 73nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 81nMAssay Description:Agonist activity at RORgammat in C57/B6 mouse Th17 cells assessed as increase in IL17A expression after 96 hrs by AlphaLISAMore data for this Ligand-Target Pair
Affinity DataEC50: 88nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Activity at RoRc in mouse CD4+ T cells assessed as inhibition of IL-17 productionMore data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Activity at RoRc in mouse CD4+ T cells assessed as inhibition of IL-17 productionMore data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 128nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 134nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 134nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 148nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 158nMAssay Description:Activity at RoRc in mouse CD4+ T cells assessed as inhibition of IL-17 productionMore data for this Ligand-Target Pair
Affinity DataEC50: 199nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 201nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 220nMAssay Description:Agonist activity at RORgammat in C57 mouse CD4+ T cells cells assessed as induction of Th17 cells differentiation by measuring increase in IL17 produ...More data for this Ligand-Target Pair
Affinity DataEC50: 230nMAssay Description:Agonist activity at RORgammat in C57 mouse CD4+ T cells cells assessed as induction of Th17 cells differentiation by measuring increase in IL17 produ...More data for this Ligand-Target Pair
Affinity DataEC50: 290nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
Affinity DataEC50: 354nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 355nMAssay Description:Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 380nMAssay Description:Agonist activity at RORgammat in mouse whole blood assessed as induction of IL-17A expressionMore data for this Ligand-Target Pair
Affinity DataEC50: 400nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
Affinity DataEC50: 440nMAssay Description:Inverse agonist activity at RORgammat in CD3/CD28/IL-1/IL-23-stimulated C57/B6 mouse whole blood assessed as reduction in IL17A production incubated ...More data for this Ligand-Target Pair
Affinity DataEC50: 450nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
Affinity DataEC50: 500nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
Affinity DataEC50: 600nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
Affinity DataEC50: 610nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
Affinity DataEC50: 630nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
