Compile Data Set for Download or QSAR
maximum 50k data
Found 56 of ec50 data for polymerid = 50007123,8498
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM60939(I-NBP)
Affinity DataEC50:  60nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50026066(1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(tr...)
Affinity DataEC50:  187nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM26948(8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-tr...)
Affinity DataEC50:  232nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50334150(1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...)
Affinity DataEC50:  354nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50088383(Amlodipine | CHEBI:2668 | Norvasc)
Affinity DataEC50:  430nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50117922((1S,2S)-2-(2-((3-(1H-benzo[d]imidazol-2-yl)propyl)...)
Affinity DataEC50:  500nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50453799(Niguldipine)
Affinity DataEC50:  750nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM86722(CAS_53772-82-0 | CAS_53772-85-3 | FLUPENTHIXOL, Al...)
Affinity DataEC50:  2.00E+3nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50017702(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)
Affinity DataEC50:  2.48E+3nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50408507(CHLOROPROMAZINE SULFOXIDE | Chlorpromazine sulfoxi...)
Affinity DataEC50:  2.70E+3nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50180659(CHEMBL3818672)
Affinity DataEC50:  3.00E+3nMAssay Description:Activation of human TREK1 expressed in CHO cells assessed as increase in channel currents at +50 mV relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50546010(CHEMBL4750599)
Affinity DataEC50: <3.10E+3nMAssay Description:Activation of human TREK1 by thallium flux mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50546001(CHEMBL4776102)
Affinity DataEC50:  3.80E+3nMAssay Description:Activation of human TREK1 by thallium flux mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50514764(CHEMBL4552751)
Affinity DataEC50:  3.91E+3nMAssay Description:Activation of recombinant human TREK1 W290A mutant expressed in HEK293T cells assessed as increase in K+ current amplitude by whole cell voltage clam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50066430(2-(4-Methyl-piperazin-1-yl)-5-(2,3,5-trichloro-phe...)
Affinity DataEC50:  4.00E+3nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50546002(CHEMBL4747631)
Affinity DataEC50:  4.30E+3nMAssay Description:Activation of human TREK1 by thallium flux mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50546000(CHEMBL4780579)
Affinity DataEC50:  4.40E+3nMAssay Description:Activation of human TREK1 by thallium flux mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50546007(CHEMBL4795261)
Affinity DataEC50:  4.60E+3nMAssay Description:Activation of human TREK1 by thallium flux mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM78433(2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]pro...)
Affinity DataEC50:  4.70E+3nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM85675(Anandamide + PMSF | CHEMBL321585)
Affinity DataEC50:  5.10E+3nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50197060(CHEMBL1417584)
Affinity DataEC50:  5.20E+3nMAssay Description:Activation of human TREK1 by thallium flux mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50053408(Haldol | Haldol Dec | Haloperidol Decanoate | R-13...)
Affinity DataEC50:  5.50E+3nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50546003(CHEMBL4759642)
Affinity DataEC50:  5.90E+3nMAssay Description:Activation of human TREK1 by thallium flux mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50546004(CHEMBL4759521)
Affinity DataEC50:  6.10E+3nMAssay Description:Activation of human TREK1 by thallium flux mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50514764(CHEMBL4552751)
Affinity DataEC50:  7.57E+3nMAssay Description:Activation of recombinant human TREK1 T156A mutant expressed in HEK293T cells assessed as increase in K+ current amplitude by whole cell voltage clam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50514764(CHEMBL4552751)
Affinity DataEC50:  7.98E+3nMAssay Description:Activation of recombinant human TREK1 I293A mutant expressed in HEK293T cells assessed as increase in K+ current amplitude by whole cell voltage clam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50101817(Adalat | Adalat Cc | Afeditab Cr | BAY-A-1040 | CH...)
Affinity DataEC50:  8.18E+3nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50254790((S)-Norfluoxetine | CHEMBL465123 | NORFLUOXETINE)
Affinity DataEC50:  9.00E+3nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50545999(CHEMBL4778307)
Affinity DataEC50:  9.50E+3nMAssay Description:Activation of human TREK1 by thallium flux mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50180656(CHEMBL3818503)
Affinity DataEC50:  9.70E+3nMAssay Description:Activation of TREK1 (unknown origin) expressed in HEK293 cells assessed as increase in current density relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50545998(CHEMBL4745050)
Affinity DataEC50:  1.28E+4nMAssay Description:Activation of human TREK1 by thallium flux mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50514764(CHEMBL4552751)
Affinity DataEC50:  1.28E+4nMAssay Description:Activation of recombinant human TREK1 expressed in HEK293T cells assessed as increase in K+ current amplitude by whole cell voltage clamp electrophys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50546012(CHEMBL4761929)
Affinity DataEC50:  1.31E+4nMAssay Description:Activation of human TREK1 by thallium flux mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50546008(CHEMBL4784090)
Affinity DataEC50:  1.37E+4nMAssay Description:Activation of human TREK1 by thallium flux mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50514764(CHEMBL4552751)
Affinity DataEC50:  1.52E+4nMAssay Description:Activation of recombinant human TREK1 G275C mutant expressed in HEK293T cells assessed as increase in K+ current amplitude by whole cell voltage clam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50546005(CHEMBL4758530)
Affinity DataEC50:  1.65E+4nMAssay Description:Activation of human TREK1 by thallium flux mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50514764(CHEMBL4552751)
Affinity DataEC50:  1.84E+4nMAssay Description:Activation of recombinant human TREK1 G275C mutant expressed in HEK293T cells assessed as increase in K+ current amplitude in presence of MTSET by wh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM81875(Fluoxetine-R-(-))
Affinity DataEC50:  1.90E+4nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM22871(13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azat...)
Affinity DataEC50:  1.97E+4nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50546006(CHEMBL4747514)
Affinity DataEC50:  2.02E+4nMAssay Description:Activation of human TREK1 by thallium flux mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50546011(CHEMBL4741659)
Affinity DataEC50:  2.24E+4nMAssay Description:Activation of human TREK1 by thallium flux mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50514764(CHEMBL4552751)
Affinity DataEC50:  2.24E+4nMAssay Description:Activation of recombinant human TREK1 F149A mutant expressed in HEK293T cells assessed as increase in K+ current amplitude by whole cell voltage clam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM190405(US9180183, Quinidine)
Affinity DataEC50:  2.41E+4nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM181128(US9138393, Diltiazem)
Affinity DataEC50:  2.48E+4nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50546009(CHEMBL4750436)
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of human TREK1 by thallium flux mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50180656(CHEMBL3818503)
Affinity DataEC50:  3.60E+4nMAssay Description:Activation of TREK1 (unknown origin) expressed in Xenopus oocytes assessed as increase in channel currentsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50012957(1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfon...)
Affinity DataEC50:  6.40E+4nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataEC50:  1.00E+5nMAssay Description:Activation of TREK1 (unknown origin) expressed in COS7 cells assessed as increase in whole cell currents at +50 mV relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50350790(BUPIVACAINE HYDROCHLORIDE | Bupivacaine | SAMPL3, ...)
Affinity DataEC50:  1.13E+5nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM50180657(CHEMBL3819108)
Affinity DataEC50:  1.25E+5nMAssay Description:Activation of TREK1 (unknown origin) expressed in Xenopus oocytes assessed as increase in channel currentsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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