Compile Data Set for Download or QSAR
maximum 50k data
Found 1402 of ec50 data for polymerid = 5447,5449
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM579314(US11479560, Title ww6-157)
Affinity DataEC50:  0nMAssay Description:HEK293 cells stably expressing OX2R are transfected with Gq alpha construct (6.4 ug per 10 cm dish) using Lipofectamine 3000 (ThermoFisher). 24 hours...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121759(CHEMBL438587 | [D-Leu15]orexin-B)
Affinity DataEC50:  0.0520nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM386188((2R,3S)-N-ethyl-2-(((cis-4-(3- fluorophenyl)cycloh...)
Affinity DataEC50:  0.0530nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM386188((2R,3S)-N-ethyl-2-(((cis-4-(3- fluorophenyl)cycloh...)
Affinity DataEC50:  0.0530nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM386188((2R,3S)-N-ethyl-2-(((cis-4-(3- fluorophenyl)cycloh...)
Affinity DataEC50:  0.0530nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121770(CHEMBL413504 | [Ala14]orexin-B)
Affinity DataEC50:  0.0650nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121788(CHEMBL441918 | [Ala11]orexin-B)
Affinity DataEC50:  0.0660nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121783(CHEMBL413434 | Orexin-B)
Affinity DataEC50:  0.0810nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121775(CHEMBL438036 | [D-Leu7]orexin-B)
Affinity DataEC50:  0.0840nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121795(CHEMBL436915 | [Gly17]orexin-B)
Affinity DataEC50:  0.0910nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121769(CHEMBL428123 | [D-Gln12]orexin-B)
Affinity DataEC50:  0.110nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM386088((2R,3S)-N-ethyl-3- ((methylsulfonyl)amino)-2-(((ci...)
Affinity DataEC50:  0.110nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM386088((2R,3S)-N-ethyl-3- ((methylsulfonyl)amino)-2-(((ci...)
Affinity DataEC50:  0.110nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM386162(US10287305, Example 117 | US10508083, Example 117 ...)
Affinity DataEC50:  0.120nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121794(CHEMBL427771 | [Ala7]orexin-B)
Affinity DataEC50:  0.120nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM386162(US10287305, Example 117 | US10508083, Example 117 ...)
Affinity DataEC50:  0.120nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM386162(US10287305, Example 117 | US10508083, Example 117 ...)
Affinity DataEC50:  0.120nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121815(CHEMBL410480 | [Ala6]orexin-B)
Affinity DataEC50:  0.120nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121765(CHEMBL437464 | [Ala13]orexin-B)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121796(CHEMBL414312 | [Ala16]orexin-B)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121810(CHEMBL409301 | [D-Ala9]orexin-B)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121777(CHEMBL265746 | [D-Ser2]orexin-B)
Affinity DataEC50:  0.150nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121817(CHEMBL437149 | [Trp11]orexin-B)
Affinity DataEC50:  0.150nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121791(CHEMBL410947 | [D-Pro4]orexin-B)
Affinity DataEC50:  0.150nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121809(CHEMBL410899 | [D-Pro5]orexin-B)
Affinity DataEC50:  0.160nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121792(CHEMBL439541 | [D-Ala19]orexin-B)
Affinity DataEC50:  0.160nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121778(CHEMBL265423 | [D-Ala3]orexin-B)
Affinity DataEC50:  0.160nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121803(CHEMBL265404 | [Ala3]orexin-B)
Affinity DataEC50:  0.180nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50586152(CHEMBL5079059)
Affinity DataEC50:  0.180nMAssay Description:Agonist activity at human OX2R expressed in CHO-K1 cells by FLIPR calcium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121766(CHEMBL410816 | [D-Arg1]orexin-B)
Affinity DataEC50:  0.190nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50594480(CHEMBL5183223)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human OX2R expressed in CHO cells incubated for 1 to 2 hrs by IP-one detection reagent based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121793(CHEMBL264342 | [D-Ala6]orexin-B)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121806(CHEMBL265907 | [Ala9]orexin-B)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121790(CHEMBL409456 | [Ala1]orexin-B)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM386174(US10287305, Example 136 | US10508083, Example 136 ...)
Affinity DataEC50:  0.220nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM386174(US10287305, Example 136 | US10508083, Example 136 ...)
Affinity DataEC50:  0.220nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM386174(US10287305, Example 136 | US10508083, Example 136 ...)
Affinity DataEC50:  0.220nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121780(CHEMBL414332 | [Ala2]orexin-B)
Affinity DataEC50:  0.220nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121784(CHEMBL266409 | [Ala12]orexin-B)
Affinity DataEC50:  0.230nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121797(CHEMBL437274 | [Ala4]orexin-B)
Affinity DataEC50:  0.230nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50594478(CHEMBL5176663)
Affinity DataEC50:  0.25nMAssay Description:Agonist activity at human OX2R expressed in CHO cells incubated for 1 to 2 hrs by IP-one detection reagent based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121773(CHEMBL386549 | [D-Asn20]orexin-B)
Affinity DataEC50:  0.260nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121767(CHEMBL409970 | [D-Ala17]orexin-B)
Affinity DataEC50:  0.260nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121781(CHEMBL275985 | [Gly22]orexin-B)
Affinity DataEC50:  0.270nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50594482(CHEMBL5203334)
Affinity DataEC50:  0.290nMAssay Description:Agonist activity at human OX2R expressed in CHO cells incubated for 1 to 2 hrs by IP-one detection reagent based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM50121786(CHEMBL442505 | [Ala5]orexin-B)
Affinity DataEC50:  0.290nMAssay Description:Agonist activity against human orexin 2 receptor; EC50; nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM386088((2R,3S)-N-ethyl-3- ((methylsulfonyl)amino)-2-(((ci...)
Affinity DataEC50:  0.290nMAssay Description:Agonist activity at human OX2R expressed in CHO-K1 cells by FLIPR calcium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM386205(US10287305, Example 179 | US10508083, Example 179 ...)
Affinity DataEC50:  0.310nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM386205(US10287305, Example 179 | US10508083, Example 179 ...)
Affinity DataEC50:  0.310nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Texas System

US Patent
LigandPNGBDBM386205(US10287305, Example 179 | US10508083, Example 179 ...)
Affinity DataEC50:  0.310nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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