Compile Data Set for Download or QSAR
maximum 50k data
Found 11 of ec50 data for polymerid = 8458
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50565590(CHEMBL4780905)
Affinity DataEC50:  0.150nMAssay Description:Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50565595(CHEMBL4785006)
Affinity DataEC50:  0.280nMAssay Description:Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50565596(CHEMBL4797870)
Affinity DataEC50:  0.690nMAssay Description:Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50565591(CHEMBL4783308)
Affinity DataEC50:  1.20nMAssay Description:Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50565589(CHEMBL4789986)
Affinity DataEC50:  2.5nMAssay Description:Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50565592(CHEMBL4788701)
Affinity DataEC50:  11nMAssay Description:Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50565593(CHEMBL4779800)
Affinity DataEC50:  40nMAssay Description:Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50565594(CHEMBL4783828)
Affinity DataEC50:  88nMAssay Description:Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50565597(CHEMBL4783880)
Affinity DataEC50:  161nMAssay Description:Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50565588(CHEMBL4779430)
Affinity DataEC50:  348nMAssay Description:Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50520945(CHEMBL4584571)
Affinity DataEC50:  6.04E+3nMAssay Description:Inhibition of PCSK9 in human HepG2 cells assessed as increase in LDL uptake after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed