Found 1996 of ic50 data for polymerid = 2154,49000039,687,7883 
Affinity DataIC50: 0.000250nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat brain cortex serotonin 5-HT2A receptor after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00105nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat brain cortex serotonin 5-HT2A receptor after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00212nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat brain cortex serotonin 5-HT2A receptor after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0217nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat brain cortex serotonin 5-HT2A receptor after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0250nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays for human 5-HT2A receptor was conducted using the 5-HT2 agonist [125]DOI as radioligand. To define nonspecific binding, 10...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0250nMAssay Description:Radioligand binding assays for human 5-HT2A receptor was conducted using the 5-HT2 agonist [125I]DOI as radioligand. To define nonspecific binding, 1...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0690nMAssay Description:R-SAT assays were performed as described previously (Weiner et al., 2001), with the following modifications. In brief, NIH-3T3 cells were grown to 80...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0820nMpH: 7.4Assay Description:Radioligand binding assays for human 5-HT2A receptor was conducted using the 5-HT2 agonist [125I]DOI as radioligand. To define nonspecific binding, 1...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 0.210nMAssay Description:Inhibition of [125I]DOI binding to 5HT2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays for human 5-HT2A receptor was conducted using the 5-HT2 agonist [125]DOI as radioligand. To define nonspecific binding, 10...More data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Radioligand binding assays for human 5-HT2A receptor was conducted using the 5-HT2 agonist [125I]DOI as radioligand. To define nonspecific binding, 1...More data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 0.290nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 0.316nMAssay Description:Compound was evaluated for its inverse agonist activity against 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in HEK293 cells measured after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.380nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 0.390nMAssay Description:Binding affinity to serotonin 5-hydroxytryptamine 2A receptors using a radioligand [3H]-ketanserin binding assay in rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.390nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibition of [125I]DOI binding to 5-hydroxytryptamine 2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Binding affinity to serotonin 5-hydroxytryptamine 2A receptors using a radioligand [3H]-ketanserin binding assay in rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2 receptor in rat cerebral cortex tissue using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMAssay Description:For total binding, a total volume of 50 ul of appropriately diluted membranes (diluted in assay buffer containing 50 mM Tris HCl (pH 7.4), 10 mM MgCl...More data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 0.480nMAssay Description:Ability to displace [3H]ketanserin (0.5 nM) from cerebral cortex of rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.480nMAssay Description:Ability to displace [3H]ketanserin (0.5 nM) from cerebral cortex of rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of [125I]DOI binding to 5-hydroxytryptamine 2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of [125I]DOI binding to 5-hydroxytryptamine 2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in avCHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.510nMpH: 7.5Assay Description:Materials for the Receptor Binding AssayIsotope ligand [3H]-Ketanserin (67.0 Ci/mmol) was purchased from PerkinElmer Company; Methysergide was purcha...More data for this Ligand-Target Pair
Affinity DataIC50: 0.510nMpH: 7.4Assay Description:Radioligand binding assays for human 5-HT2A receptor was conducted using the 5-HT2 agonist [125I]DOI as radioligand. To define nonspecific binding, 1...More data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Inhibition of [125I]DOI binding to 5HT2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:CHO-K1/5-HT2A cells in the logarithmic growth phase were seeded into a 384-well plate at a density of 10000 cells per well, and cultured in a 37° C.,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMAssay Description:Inhibition of [125I]DOI binding to 5HT2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of [3H]-ketanserin binding to rat frontal cortex membrane 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) after 10 mins by calcium 5 dye based FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.610nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.640nMAssay Description:Displacement of [3H]ketanserin human recombinant 5-HT2A receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in avCHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:In vitro inhibition of [125I]DOI binding to 5-hydroxytryptamine 2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 0.708nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in CHOK1 cells assessed as inhibition of 5-HT induced inositol phosphate production incubated f...More data for this Ligand-Target Pair
