Compile Data Set for Download or QSAR
maximum 50k data
Found 35 of ic50 data for polymerid = 2445,50004827
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  0.5nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of bovine lens cytosolic leucine aminopeptidase by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransforming growth factor beta-1 proprotein(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50353187(CHEMBL1829511)
Affinity DataIC50:  11nMAssay Description:Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransforming growth factor beta-1 proprotein(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50184879(CHEMBL424676 | dimethyl-{2-[(4-{4-[3-(pyridin-2-yl...)
Affinity DataIC50:  19nMAssay Description:Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransforming growth factor beta-1 proprotein(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50353188(CHEMBL1829512)
Affinity DataIC50:  32nMAssay Description:Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransforming growth factor beta-1 proprotein(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50353184(CHEMBL1828640)
Affinity DataIC50:  68nMAssay Description:Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransforming growth factor beta-1 proprotein(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50353185(CHEMBL1829504)
Affinity DataIC50:  77nMAssay Description:Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransforming growth factor beta-1 proprotein(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50353186(CHEMBL1829505)
Affinity DataIC50:  88nMAssay Description:Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransforming growth factor beta-1 proprotein(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50184872(4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-y...)
Affinity DataIC50:  446nMAssay Description:Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransforming growth factor beta-1 proprotein(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50585028(CHEMBL5078185)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of TGF beta 1 (unknown origin) expressed in HEK293 cells transfected with Smad2/3 responsive reporter plasmid incubated for 4 hrs by dual ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransforming growth factor beta-1 proprotein(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50525413(CHEMBL4448117)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of TGF beta 1 (unknown origin) expressed in HEK293 cells transfected with Smad2/3 responsive reporter plasmid incubated for 4 hrs by dual ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM50336496(2-aminocycloheptanone hydrochloride | CHEMBL166862...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of bovine lens cytosolic leucine aminopeptidase by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23980((3Z)-3-{[(5-phenylpentyl)oxy]imino}-1,2,3,4-tetrah...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23977((3Z)-3-[(2-phenylethoxy)imino]-1,2,3,4-tetrahydron...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23979((3Z)-3-[(4-phenylbutoxy)imino]-1,2,3,4-tetrahydron...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23973(3-amino-1,2,3,4-tetrahydronaphthalen-2-one hydroch...)
Affinity DataIC50:  1.20E+5nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23973(3-amino-1,2,3,4-tetrahydronaphthalen-2-one hydroch...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of bovine lens cytosolic leucine aminopeptidase by Dixon plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23990(3-amino-1,2,3,4-tetrahydroquinolin-2-one hydrochlo...)
Affinity DataIC50: >1.00E+6nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23988(2-amino-1,2,3,4-tetrahydroisoquinolin-3-one | N-Su...)
Affinity DataIC50:  1.00E+6nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23974((3Z)-3-(hydroxyimino)-1,2,3,4-tetrahydronaphthalen...)
Affinity DataIC50: >1.00E+6nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM50336493(1-Aminoindan-2-one, hydrochloride | CHEMBL1668624)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of bovine lens cytosolic leucine aminopeptidase by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM50336494(6-amino-5,6,8,9-tetrahydrobenzocycloheptene-7-one,...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of bovine lens cytosolic leucine aminopeptidase by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM50336495(7-Amino-5,7,8,9-tetrahydro-benzocyclohepten-6-one,...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of bovine lens cytosolic leucine aminopeptidase by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23986(3,4-dihydro-1H-2-benzothiopyran-3-one | isothiochr...)
Affinity DataIC50: >1.00E+6nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM50336497(7-Amino-5,7,8,9-tetrahydrobenzocyclohepten-6-one,6...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of bovine lens cytosolic leucine aminopeptidase by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM50336499(CHEMBL1668630 | cis-7-amino-6,7,8,9-tetrahydro-5H-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of bovine lens cytosolic leucine aminopeptidase by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23985(3,4-dihydro-1H-2-benzopyran-3-one | isochromanone,...)
Affinity DataIC50: >1.00E+6nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23984(3-amino-1,2,3,4-tetrahydronaphthalene-2-phosphonic...)
Affinity DataIC50: >1.00E+6nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23982(1-(3-amino-1,2,3,4-tetrahydronaphthalen-2-yl)ethan...)
Affinity DataIC50: >1.00E+6nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23981((2S)-1,2,3,4-Tetrahydro-naphthalen-2-ylamine | 1,2...)
Affinity DataIC50: >1.00E+6nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23978((3Z)-3-[(3-phenylpropoxy)imino]-1,2,3,4-tetrahydro...)
Affinity DataIC50: >1.00E+6nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23976((3Z)-3-[(benzyloxy)imino]-1,2,3,4-tetrahydronaphth...)
Affinity DataIC50: >1.00E+6nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23975((3Z)-3-(methoxyimino)-1,2,3,4-tetrahydronaphthalen...)
Affinity DataIC50: >1.00E+6nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23989(1,2,3,4-tetrahydronaphthalen-2-one | CHEMBL191664 ...)
Affinity DataIC50: >1.00E+6nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23987(2-hydroxy-1,2,3,4-tetrahydroisoquinolin-3-one | CH...)
Affinity DataIC50: >1.00E+6nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed