Compile Data Set for Download or QSAR
maximum 50k data
Found 19 of ic50 data for polymerid = 3674
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human MSK2 using GRPRTSSFAEG as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  11.3nMAssay Description:Inhibition of human MSK2 using GRPRTSSFAEG as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50601138(CHEMBL5184056)
Affinity DataIC50:  20nMAssay Description:Inhibition of MSK2 (unknown origin) FAM-PSKPAATRKRRWSAPESR-NH2 as substrate preincubated for 1 hr followed by activation with ERK2 and substrate addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50601139(CHEMBL5190298)
Affinity DataIC50:  79nMAssay Description:Inhibition of MSK2 (unknown origin) FAM-PSKPAATRKRRWSAPESR-NH2 as substrate preincubated for 1 hr followed by activation with ERK2 and substrate addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50601160(CHEMBL5187801)
Affinity DataIC50:  794nMAssay Description:Inhibition of MSK2 (unknown origin) FAM-PSKPAATRKRRWSAPESR-NH2 as substrate preincubated for 1 hr followed by activation with ERK2 and substrate addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of MSK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM27344(2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyri...)
Affinity DataIC50:  3.01E+3nMAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50601147(CHEMBL5183977)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of MSK2 (unknown origin) FAM-PSKPAATRKRRWSAPESR-NH2 as substrate preincubated for 1 hr followed by activation with ERK2 and substrate addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50601137(CHEMBL5198790)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of MSK2 (unknown origin) FAM-PSKPAATRKRRWSAPESR-NH2 as substrate preincubated for 1 hr followed by activation with ERK2 and substrate addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50436476(CHEMBL2397316)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of MSK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human MSK2 (2 to end residues) using GRPRTSSFAEGKK as substrate incubated for 40 mins in presence of [gamma-33ATP by radiom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50401152(CHEMBL2205766)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of RPS6KA4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human MSK2 using [GRPRTSSFAEG] as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MSK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50359359(CHEMBL1929238)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MSK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM30192(Pyrrolopyridine, 23)
Affinity DataIC50:  5.80E+4nMAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant full length human GST-tagged RPS6KA4 expressed in baculovirus expression system using ser/Thr01 peptide as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM30178(Pyrrolopyridine, 9)
Affinity DataIC50:  1.48E+5nMAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM30185(CHEMBL226403 | Pyrrolopyridine, 16)
Affinity DataIC50: >2.00E+5nMAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed