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Compile Data Set for Download or QSAR

Found 89 hits of ic50 data for polymerid = 49001044   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
TG 1019


(Homo sapiens (Human))
BDBM50465693
PNG
(CHEMBL4283608)
Show SMILES C[C@H](CC(O)=O)CC(=O)c1c(CCCCCCc2ccccc2)n(C)c2ccc(Cl)cc12
Show InChI InChI=1S/C27H32ClNO3/c1-19(17-26(31)32)16-25(30)27-22-18-21(28)14-15-23(22)29(2)24(27)13-9-4-3-6-10-20-11-7-5-8-12-20/h5,7-8,11-12,14-15,18-19H,3-4,6,9-10,13,16-17H2,1-2H3,(H,31,32)/t19-/m0/s1
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n/an/a 0.120n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50465682
PNG
(CHEMBL4287941)
Show SMILES CC(CC(O)=O)CC(=O)c1c(CCCCCCc2ccccc2)n(C)c2ccc(Cl)cc12
Show InChI InChI=1S/C27H32ClNO3/c1-19(17-26(31)32)16-25(30)27-22-18-21(28)14-15-23(22)29(2)24(27)13-9-4-3-6-10-20-11-7-5-8-12-20/h5,7-8,11-12,14-15,18-19H,3-4,6,9-10,13,16-17H2,1-2H3,(H,31,32)
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n/an/a 0.280n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50465685
PNG
(CHEMBL4281149)
Show SMILES C[C@H](CC(O)=O)CC(=O)c1c([C@@H](O)CCCCCc2ccccc2)n(C)c2ccc(Cl)cc12
Show InChI InChI=1S/C27H32ClNO4/c1-18(16-25(32)33)15-24(31)26-21-17-20(28)13-14-22(21)29(2)27(26)23(30)12-8-4-7-11-19-9-5-3-6-10-19/h3,5-6,9-10,13-14,17-18,23,30H,4,7-8,11-12,15-16H2,1-2H3,(H,32,33)/t18-,23-/m0/s1
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n/an/a 0.380n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50465690
PNG
(CHEMBL4282356)
Show SMILES CC(CC(O)=O)CC(=O)n1c(CCCCCc2ccccc2)cc2ccc(Cl)cc12
Show InChI InChI=1S/C25H28ClNO3/c1-18(15-25(29)30)14-24(28)27-22(16-20-12-13-21(26)17-23(20)27)11-7-3-6-10-19-8-4-2-5-9-19/h2,4-5,8-9,12-13,16-18H,3,6-7,10-11,14-15H2,1H3,(H,29,30)
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n/an/a 2.10n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50054792
PNG
(CHEMBL3341973)
Show SMILES CCCCCCc1cc2ccc(Cl)cc2n1C(=O)C[C@H](C)CC(O)=O
Show InChI InChI=1S/C20H26ClNO3/c1-3-4-5-6-7-17-12-15-8-9-16(21)13-18(15)22(17)19(23)10-14(2)11-20(24)25/h8-9,12-14H,3-7,10-11H2,1-2H3,(H,24,25)/t14-/m0/s1
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n/an/a 2.20n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of calcium mobilization by fluorescence assay


ACS Med Chem Lett 5: 815-9 (2014)


Article DOI: 10.1021/ml500161v
BindingDB Entry DOI: 10.7270/Q2H70HHM
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50054794
PNG
(CHEMBL3341971)
Show SMILES CCCCCCc1c(C(=O)C[C@@H](C)CC(O)=O)c2cc(Cl)ccc2n1C
Show InChI InChI=1S/C21H28ClNO3/c1-4-5-6-7-8-18-21(19(24)11-14(2)12-20(25)26)16-13-15(22)9-10-17(16)23(18)3/h9-10,13-14H,4-8,11-12H2,1-3H3,(H,25,26)/t14-/m1/s1
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n/an/a 2.70n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of calcium mobilization by fluorescence assay


ACS Med Chem Lett 5: 815-9 (2014)


Article DOI: 10.1021/ml500161v
BindingDB Entry DOI: 10.7270/Q2H70HHM
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50024458
PNG
(5-oxo-ETE | CHEMBL18028 | ETE-5-Oxo)
Show SMILES CCCCC\C=C/C\C=C/CC=CC=CC(=O)CCCC(O)=O
Show InChI InChI=1S/C20H30O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12?,16-14?
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n/an/a 3n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Desensitization of 5-oxo-ETE receptor in indo-1-labeled human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization


Bioorg Med Chem Lett 21: 1987-90 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.021
BindingDB Entry DOI: 10.7270/Q2XW4K3V
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50054793
PNG
(CHEMBL3341972)
Show SMILES CCCCCCc1c(C(=O)C[C@H](C)CC(O)=O)c2cc(Cl)ccc2n1C
Show InChI InChI=1S/C21H28ClNO3/c1-4-5-6-7-8-18-21(19(24)11-14(2)12-20(25)26)16-13-15(22)9-10-17(16)23(18)3/h9-10,13-14H,4-8,11-12H2,1-3H3,(H,25,26)/t14-/m0/s1
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n/an/a 6n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50054793
PNG
(CHEMBL3341972)
Show SMILES CCCCCCc1c(C(=O)C[C@H](C)CC(O)=O)c2cc(Cl)ccc2n1C
Show InChI InChI=1S/C21H28ClNO3/c1-4-5-6-7-8-18-21(19(24)11-14(2)12-20(25)26)16-13-15(22)9-10-17(16)23(18)3/h9-10,13-14H,4-8,11-12H2,1-3H3,(H,25,26)/t14-/m0/s1
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n/an/a 6n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


Bioorg Med Chem Lett 27: 4770-4776 (2017)


Article DOI: 10.1016/j.bmcl.2017.08.034
BindingDB Entry DOI: 10.7270/Q2W098DS
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50054793
PNG
(CHEMBL3341972)
Show SMILES CCCCCCc1c(C(=O)C[C@H](C)CC(O)=O)c2cc(Cl)ccc2n1C
Show InChI InChI=1S/C21H28ClNO3/c1-4-5-6-7-8-18-21(19(24)11-14(2)12-20(25)26)16-13-15(22)9-10-17(16)23(18)3/h9-10,13-14H,4-8,11-12H2,1-3H3,(H,25,26)/t14-/m0/s1
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n/an/a 6n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of calcium mobilization by fluorescence assay


ACS Med Chem Lett 5: 815-9 (2014)


Article DOI: 10.1021/ml500161v
BindingDB Entry DOI: 10.7270/Q2H70HHM
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446952
PNG
(CHEMBL3115775)
Show SMILES CCCCCCc1c(C(=O)CC(C)CC(O)=O)c2cc(Cl)ccc2n1C
Show InChI InChI=1S/C21H28ClNO3/c1-4-5-6-7-8-18-21(19(24)11-14(2)12-20(25)26)16-13-15(22)9-10-17(16)23(18)3/h9-10,13-14H,4-8,11-12H2,1-3H3,(H,25,26)
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n/an/a 6n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446953
PNG
(CHEMBL3115774)
Show SMILES CCCCCCc1cc2ccc(Cl)cc2n1C(=O)CC(C)CC(O)=O
Show InChI InChI=1S/C20H26ClNO3/c1-3-4-5-6-7-17-12-15-8-9-16(21)13-18(15)22(17)19(23)10-14(2)11-20(24)25/h8-9,12-14H,3-7,10-11H2,1-2H3,(H,24,25)
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n/an/a 7n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446953
PNG
(CHEMBL3115774)
Show SMILES CCCCCCc1cc2ccc(Cl)cc2n1C(=O)CC(C)CC(O)=O
Show InChI InChI=1S/C20H26ClNO3/c1-3-4-5-6-7-17-12-15-8-9-16(21)13-18(15)22(17)19(23)10-14(2)11-20(24)25/h8-9,12-14H,3-7,10-11H2,1-2H3,(H,24,25)
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n/an/a 7n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of calcium mobilization by fluorescence assay


ACS Med Chem Lett 5: 815-9 (2014)


Article DOI: 10.1021/ml500161v
BindingDB Entry DOI: 10.7270/Q2H70HHM
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50341133
PNG
((6E,8Z,11Z,14Z)-20,20,20-trifluoro-5-oxoicosa-6,8,...)
Show SMILES OC(=O)CCCC(=O)C=CC=CC\C=C/C\C=C/CCCCC(F)(F)F
Show InChI InChI=1S/C20H27F3O3/c21-20(22,23)17-12-10-8-6-4-2-1-3-5-7-9-11-14-18(24)15-13-16-19(25)26/h1,3-4,6-7,9,11,14H,2,5,8,10,12-13,15-17H2,(H,25,26)/b3-1-,6-4-,9-7?,14-11?
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n/an/a 7.5n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Desensitization of 5-oxo-ETE receptor in indo-1-labeled human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization


Bioorg Med Chem Lett 21: 1987-90 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.021
BindingDB Entry DOI: 10.7270/Q2XW4K3V
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50465692
PNG
(CHEMBL4284672)
Show SMILES CC(CC(O)=O)CC(=O)c1c(CCCCCc2ccccc2)n(C)c2ccc(Cl)cc12
Show InChI InChI=1S/C26H30ClNO3/c1-18(16-25(30)31)15-24(29)26-21-17-20(27)13-14-22(21)28(2)23(26)12-8-4-7-11-19-9-5-3-6-10-19/h3,5-6,9-10,13-14,17-18H,4,7-8,11-12,15-16H2,1-2H3,(H,30,31)
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n/an/a 11n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50465681
PNG
(CHEMBL4277299)
Show SMILES CC(CC(O)=O)CC(=O)n1c(CCCCCCc2ccccc2)cc2ccc(Cl)cc12
Show InChI InChI=1S/C26H30ClNO3/c1-19(16-26(30)31)15-25(29)28-23(17-21-13-14-22(27)18-24(21)28)12-8-3-2-5-9-20-10-6-4-7-11-20/h4,6-7,10-11,13-14,17-19H,2-3,5,8-9,12,15-16H2,1H3,(H,30,31)
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n/an/a 12n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446952
PNG
(CHEMBL3115775)
Show SMILES CCCCCCc1c(C(=O)CC(C)CC(O)=O)c2cc(Cl)ccc2n1C
Show InChI InChI=1S/C21H28ClNO3/c1-4-5-6-7-8-18-21(19(24)11-14(2)12-20(25)26)16-13-15(22)9-10-17(16)23(18)3/h9-10,13-14H,4-8,11-12H2,1-3H3,(H,25,26)
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n/an/a 16n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


Bioorg Med Chem Lett 27: 4770-4776 (2017)


Article DOI: 10.1016/j.bmcl.2017.08.034
BindingDB Entry DOI: 10.7270/Q2W098DS
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446952
PNG
(CHEMBL3115775)
Show SMILES CCCCCCc1c(C(=O)CC(C)CC(O)=O)c2cc(Cl)ccc2n1C
Show InChI InChI=1S/C21H28ClNO3/c1-4-5-6-7-8-18-21(19(24)11-14(2)12-20(25)26)16-13-15(22)9-10-17(16)23(18)3/h9-10,13-14H,4-8,11-12H2,1-3H3,(H,25,26)
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n/an/a 17n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446953
PNG
(CHEMBL3115774)
Show SMILES CCCCCCc1cc2ccc(Cl)cc2n1C(=O)CC(C)CC(O)=O
Show InChI InChI=1S/C20H26ClNO3/c1-3-4-5-6-7-17-12-15-8-9-16(21)13-18(15)22(17)19(23)10-14(2)11-20(24)25/h8-9,12-14H,3-7,10-11H2,1-2H3,(H,24,25)
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n/an/a 17n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446953
PNG
(CHEMBL3115774)
Show SMILES CCCCCCc1cc2ccc(Cl)cc2n1C(=O)CC(C)CC(O)=O
Show InChI InChI=1S/C20H26ClNO3/c1-3-4-5-6-7-17-12-15-8-9-16(21)13-18(15)22(17)19(23)10-14(2)11-20(24)25/h8-9,12-14H,3-7,10-11H2,1-2H3,(H,24,25)
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n/an/a 18n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at 5-oxo-ETE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced Ca2+ mobilization incubated for 2 mins pri...


Bioorg Med Chem Lett 24: 3385-8 (2014)


Article DOI: 10.1016/j.bmcl.2014.05.090
BindingDB Entry DOI: 10.7270/Q2G162F7
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50465695
PNG
(CHEMBL4291346)
Show SMILES CC(CC(O)=O)CC(=O)n1c(CCCCc2ccccc2)cc2ccc(Cl)cc12
Show InChI InChI=1S/C24H26ClNO3/c1-17(14-24(28)29)13-23(27)26-21(15-19-11-12-20(25)16-22(19)26)10-6-5-9-18-7-3-2-4-8-18/h2-4,7-8,11-12,15-17H,5-6,9-10,13-14H2,1H3,(H,28,29)
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n/an/a 18n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50262197
PNG
(CHEMBL4084871)
Show SMILES CCCCCCCCCCCc1c(C(=O)CC(C)CC(O)=O)c2cc(Cl)ccc2n1C
Show InChI InChI=1S/C26H38ClNO3/c1-4-5-6-7-8-9-10-11-12-13-23-26(24(29)16-19(2)17-25(30)31)21-18-20(27)14-15-22(21)28(23)3/h14-15,18-19H,4-13,16-17H2,1-3H3,(H,30,31)
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n/an/a 23n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


Bioorg Med Chem Lett 27: 4770-4776 (2017)


Article DOI: 10.1016/j.bmcl.2017.08.034
BindingDB Entry DOI: 10.7270/Q2W098DS
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50465684
PNG
(CHEMBL4291464)
Show SMILES C[C@@H](CC(O)=O)CC(=O)c1c(CCCCCCc2ccccc2)n(C)c2ccc(Cl)cc12
Show InChI InChI=1S/C27H32ClNO3/c1-19(17-26(31)32)16-25(30)27-22-18-21(28)14-15-23(22)29(2)24(27)13-9-4-3-6-10-20-11-7-5-8-12-20/h5,7-8,11-12,14-15,18-19H,3-4,6,9-10,13,16-17H2,1-2H3,(H,31,32)/t19-/m1/s1
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n/an/a 23n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446954
PNG
(CHEMBL3115793)
Show SMILES CCCCCCc1c(C(=O)CC(C)CC(O)=O)c2cc(Br)ccc2n1C
Show InChI InChI=1S/C21H28BrNO3/c1-4-5-6-7-8-18-21(19(24)11-14(2)12-20(25)26)16-13-15(22)9-10-17(16)23(18)3/h9-10,13-14H,4-8,11-12H2,1-3H3,(H,25,26)
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n/an/a 26n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446952
PNG
(CHEMBL3115775)
Show SMILES CCCCCCc1c(C(=O)CC(C)CC(O)=O)c2cc(Cl)ccc2n1C
Show InChI InChI=1S/C21H28ClNO3/c1-4-5-6-7-8-18-21(19(24)11-14(2)12-20(25)26)16-13-15(22)9-10-17(16)23(18)3/h9-10,13-14H,4-8,11-12H2,1-3H3,(H,25,26)
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n/an/a 28n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446953
PNG
(CHEMBL3115774)
Show SMILES CCCCCCc1cc2ccc(Cl)cc2n1C(=O)CC(C)CC(O)=O
Show InChI InChI=1S/C20H26ClNO3/c1-3-4-5-6-7-17-12-15-8-9-16(21)13-18(15)22(17)19(23)10-14(2)11-20(24)25/h8-9,12-14H,3-7,10-11H2,1-2H3,(H,24,25)
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n/an/a 28n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446953
PNG
(CHEMBL3115774)
Show SMILES CCCCCCc1cc2ccc(Cl)cc2n1C(=O)CC(C)CC(O)=O
Show InChI InChI=1S/C20H26ClNO3/c1-3-4-5-6-7-17-12-15-8-9-16(21)13-18(15)22(17)19(23)10-14(2)11-20(24)25/h8-9,12-14H,3-7,10-11H2,1-2H3,(H,24,25)
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n/an/a 30n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in anti-CD49d-labeled eosinophils assessed as inhibition of 5-oxo-ETE-induced F-actin ...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446961
PNG
(CHEMBL3115786)
Show SMILES CCCCCCc1cc2ccc(Br)cc2n1C(=O)CC(C)CC(O)=O
Show InChI InChI=1S/C20H26BrNO3/c1-3-4-5-6-7-17-12-15-8-9-16(21)13-18(15)22(17)19(23)10-14(2)11-20(24)25/h8-9,12-14H,3-7,10-11H2,1-2H3,(H,24,25)
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n/an/a 30n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446952
PNG
(CHEMBL3115775)
Show SMILES CCCCCCc1c(C(=O)CC(C)CC(O)=O)c2cc(Cl)ccc2n1C
Show InChI InChI=1S/C21H28ClNO3/c1-4-5-6-7-8-18-21(19(24)11-14(2)12-20(25)26)16-13-15(22)9-10-17(16)23(18)3/h9-10,13-14H,4-8,11-12H2,1-3H3,(H,25,26)
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n/an/a 33n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in anti-CD49d-labeled eosinophils assessed as inhibition of 5-oxo-ETE-induced F-actin ...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50465680
PNG
(CHEMBL4278772)
Show SMILES CC(CC(O)=O)CC(=O)c1c(CCCCCC(F)(F)F)n(C)c2ccc(Cl)cc12
Show InChI InChI=1S/C21H25ClF3NO3/c1-13(11-19(28)29)10-18(27)20-15-12-14(22)7-8-16(15)26(2)17(20)6-4-3-5-9-21(23,24)25/h7-8,12-13H,3-6,9-11H2,1-2H3,(H,28,29)
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n/an/a 38n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50465683
PNG
(CHEMBL4279605)
Show SMILES CC(CC(O)=O)CC(=O)c1c(CCCCc2ccccc2)n(C)c2ccc(Cl)cc12
Show InChI InChI=1S/C25H28ClNO3/c1-17(15-24(29)30)14-23(28)25-20-16-19(26)12-13-21(20)27(2)22(25)11-7-6-10-18-8-4-3-5-9-18/h3-5,8-9,12-13,16-17H,6-7,10-11,14-15H2,1-2H3,(H,29,30)
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n/an/a 38n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446955
PNG
(CHEMBL3115792)
Show SMILES CCCCCCc1c(C(=O)CC(C)CC(O)=O)c2ccc(Cl)cc2n1C
Show InChI InChI=1S/C21H28ClNO3/c1-4-5-6-7-8-17-21(19(24)11-14(2)12-20(25)26)16-10-9-15(22)13-18(16)23(17)3/h9-10,13-14H,4-8,11-12H2,1-3H3,(H,25,26)
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n/an/a 81n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446965
PNG
(CHEMBL3115782)
Show SMILES CCCCCCc1cc2ccccc2n1C(=O)CC(C)CC(O)=O
Show InChI InChI=1S/C20H27NO3/c1-3-4-5-6-10-17-14-16-9-7-8-11-18(16)21(17)19(22)12-15(2)13-20(23)24/h7-9,11,14-15H,3-6,10,12-13H2,1-2H3,(H,23,24)
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n/an/a 90n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50465686
PNG
(CHEMBL4277207)
Show SMILES C[C@@H](CC(O)=O)CC(=O)c1c([C@@H](O)CCCCCc2ccccc2)n(C)c2ccc(Cl)cc12
Show InChI InChI=1S/C27H32ClNO4/c1-18(16-25(32)33)15-24(31)26-21-17-20(28)13-14-22(21)29(2)27(26)23(30)12-8-4-7-11-19-9-5-3-6-10-19/h3,5-6,9-10,13-14,17-18,23,30H,4,7-8,11-12,15-16H2,1-2H3,(H,32,33)/t18-,23+/m1/s1
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n/an/a 120n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446964
PNG
(CHEMBL3115783)
Show SMILES CCCCCCc1c(C)c2ccccc2n1C(=O)CC(C)CC(O)=O
Show InChI InChI=1S/C21H29NO3/c1-4-5-6-7-11-18-16(3)17-10-8-9-12-19(17)22(18)20(23)13-15(2)14-21(24)25/h8-10,12,15H,4-7,11,13-14H2,1-3H3,(H,24,25)
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n/an/a 136n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446962
PNG
(CHEMBL3115785)
Show SMILES CCCCCCc1cc2cc(Cl)ccc2n1C(=O)CC(C)CC(O)=O
Show InChI InChI=1S/C20H26ClNO3/c1-3-4-5-6-7-17-13-15-12-16(21)8-9-18(15)22(17)19(23)10-14(2)11-20(24)25/h8-9,12-14H,3-7,10-11H2,1-2H3,(H,24,25)
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n/an/a 141n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50465691
PNG
(CHEMBL4280693)
Show SMILES CC(CC(O)=O)CC(=O)n1c(CCCc2ccccc2)cc2ccc(Cl)cc12
Show InChI InChI=1S/C23H24ClNO3/c1-16(13-23(27)28)12-22(26)25-20(9-5-8-17-6-3-2-4-7-17)14-18-10-11-19(24)15-21(18)25/h2-4,6-7,10-11,14-16H,5,8-9,12-13H2,1H3,(H,27,28)
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n/an/a 210n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50465688
PNG
(CHEMBL4287509)
Show SMILES CC(CC(O)=O)CC(=O)c1c(CCCc2ccccc2)n(C)c2ccc(Cl)cc12
Show InChI InChI=1S/C24H26ClNO3/c1-16(14-23(28)29)13-22(27)24-19-15-18(25)11-12-20(19)26(2)21(24)10-6-9-17-7-4-3-5-8-17/h3-5,7-8,11-12,15-16H,6,9-10,13-14H2,1-2H3,(H,28,29)
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n/an/a 223n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50465689
PNG
(CHEMBL4285167)
Show SMILES C[C@H](CC(O)=O)CC(=O)c1c([C@H](O)CCCCCc2ccccc2)n(C)c2ccc(Cl)cc12
Show InChI InChI=1S/C27H32ClNO4/c1-18(16-25(32)33)15-24(31)26-21-17-20(28)13-14-22(21)29(2)27(26)23(30)12-8-4-7-11-19-9-5-3-6-10-19/h3,5-6,9-10,13-14,17-18,23,30H,4,7-8,11-12,15-16H2,1-2H3,(H,32,33)/t18-,23+/m0/s1
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n/an/a 260n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446956
PNG
(CHEMBL3115791)
Show SMILES CCCCCCc1c(C(=O)CC(C)CC(O)=O)c2ccccc2n1C
Show InChI InChI=1S/C21H29NO3/c1-4-5-6-7-12-18-21(19(23)13-15(2)14-20(24)25)16-10-8-9-11-17(16)22(18)3/h8-11,15H,4-7,12-14H2,1-3H3,(H,24,25)
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n/an/a 314n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446960
PNG
(CHEMBL3115787)
Show SMILES CCCCCCc1cc2ccc(OC)cc2n1C(=O)CC(C)CC(O)=O
Show InChI InChI=1S/C21H29NO4/c1-4-5-6-7-8-17-13-16-9-10-18(26-3)14-19(16)22(17)20(23)11-15(2)12-21(24)25/h9-10,13-15H,4-8,11-12H2,1-3H3,(H,24,25)
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n/an/a 323n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50431178
PNG
(CHEMBL2332562)
Show SMILES OC(=O)CCCC(=O)n1ccc2ccc(Cl)cc12
Show InChI InChI=1S/C13H12ClNO3/c14-10-5-4-9-6-7-15(11(9)8-10)12(16)2-1-3-13(17)18/h4-8H,1-3H2,(H,17,18)
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n/an/a 400n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as 5-oxo-ETE-induced Ca2+ mobilization incubated for 2 mins prior to 5-oxo-ETE addi...


J Med Chem 56: 3725-32 (2013)


Article DOI: 10.1021/jm400480j
BindingDB Entry DOI: 10.7270/Q2RB75XQ
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446953
PNG
(CHEMBL3115774)
Show SMILES CCCCCCc1cc2ccc(Cl)cc2n1C(=O)CC(C)CC(O)=O
Show InChI InChI=1S/C20H26ClNO3/c1-3-4-5-6-7-17-12-15-8-9-16(21)13-18(15)22(17)19(23)10-14(2)11-20(24)25/h8-9,12-14H,3-7,10-11H2,1-2H3,(H,24,25)
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n/an/a 402n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in neutrophils assessed as inhibition of 5-oxo-ETE-induced cell migration after 2 hrs ...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446952
PNG
(CHEMBL3115775)
Show SMILES CCCCCCc1c(C(=O)CC(C)CC(O)=O)c2cc(Cl)ccc2n1C
Show InChI InChI=1S/C21H28ClNO3/c1-4-5-6-7-8-18-21(19(24)11-14(2)12-20(25)26)16-13-15(22)9-10-17(16)23(18)3/h9-10,13-14H,4-8,11-12H2,1-3H3,(H,25,26)
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n/an/a 454n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in neutrophils assessed as inhibition of 5-oxo-ETE-induced cell migration after 2 hrs ...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50046281
PNG
(CHEMBL3311230)
Show SMILES CCCC\C=C/c1cc2ccc(Cl)cc2n1C(=O)CC(C)CC(O)=O
Show InChI InChI=1S/C20H24ClNO3/c1-3-4-5-6-7-17-12-15-8-9-16(21)13-18(15)22(17)19(23)10-14(2)11-20(24)25/h6-9,12-14H,3-5,10-11H2,1-2H3,(H,24,25)/b7-6-
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n/an/a 460n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at 5-oxo-ETE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced Ca2+ mobilization incubated for 2 mins pri...


Bioorg Med Chem Lett 24: 3385-8 (2014)


Article DOI: 10.1016/j.bmcl.2014.05.090
BindingDB Entry DOI: 10.7270/Q2G162F7
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446976
PNG
(CHEMBL3115777 | CHEMBL3115778)
Show SMILES CCCCC\C=C/C[C@H](O)\C=C\C=CC=CC(=O)CCCC(O)=O
Show InChI InChI=1S/C20H30O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h6-11,14-15,18,21H,2-5,12-13,16-17H2,1H3,(H,23,24)/b8-7?,9-6-,14-10+,15-11?/t18-/m0/s1
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n/an/a 500n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization by spectrofluorometric anal...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50465687
PNG
(CHEBI:34146 | CHEMBL1526258)
Show SMILES CCCCC\C=C/C[C@H](O)\C=C\C=C/C\C=C/CCCC(O)=O
Show InChI InChI=1S/C20H32O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h7-11,13-14,17,19,21H,2-6,12,15-16,18H2,1H3,(H,22,23)/b9-7-,11-8-,13-10-,17-14+/t19-/m0/s1
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n/an/a 500n/an/an/an/an/an/a



Florida Institute of Technology

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...


J Med Chem 61: 5934-5948 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00154
BindingDB Entry DOI: 10.7270/Q22F7R48
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446969
PNG
(CHEMBL3115800)
Show SMILES CCCCCCCCC\C=C/c1cc2ccccc2n1C(=O)CCCC(O)=O
Show InChI InChI=1S/C24H33NO3/c1-2-3-4-5-6-7-8-9-10-15-21-19-20-14-11-12-16-22(20)25(21)23(26)17-13-18-24(27)28/h10-12,14-16,19H,2-9,13,17-18H2,1H3,(H,27,28)/b15-10-
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n/an/a 550n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446957
PNG
(CHEMBL3115790)
Show SMILES CCCCCCc1c(C(=O)CCCC(O)=O)c2cc(Cl)ccc2n1C
Show InChI InChI=1S/C20H26ClNO3/c1-3-4-5-6-8-17-20(18(23)9-7-10-19(24)25)15-13-14(21)11-12-16(15)22(17)2/h11-13H,3-10H2,1-2H3,(H,24,25)
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n/an/a 566n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
TG 1019


(Homo sapiens (Human))
BDBM50446971
PNG
(CHEMBL3115798)
Show SMILES CCCCCCCCc1cc2ccccc2n1C(=O)CCCC(O)=O
Show InChI InChI=1S/C21H29NO3/c1-2-3-4-5-6-7-12-18-16-17-11-8-9-13-19(17)22(18)20(23)14-10-15-21(24)25/h8-9,11,13,16H,2-7,10,12,14-15H2,1H3,(H,24,25)
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n/an/a 570n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...


J Med Chem 57: 364-77 (2014)


Article DOI: 10.1021/jm401292m
BindingDB Entry DOI: 10.7270/Q2N87C82
More data for this
Ligand-Target Pair
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