Compile Data Set for Download or QSAR
maximum 50k data
Found 146 of ic50 data for polymerid = 50000136,50001742,50002606
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50471296(CHEMBL87935)
Affinity DataIC50:  0.700nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290686(9-((E)-4-((2S,3R,4R,5S)-3,4-dihydroxy-5-(((2S,3S)-...)
Affinity DataIC50:  0.800nMAssay Description:Compound was evaluated for inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50290686(9-((E)-4-((2S,3R,4R,5S)-3,4-dihydroxy-5-(((2S,3S)-...)
Affinity DataIC50:  0.850nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50471292(CHEMBL315230)
Affinity DataIC50:  1.10nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50471294(CHEMBL276855)
Affinity DataIC50:  1.90nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
Riken (The Institute Of Physical And Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217841(REVEROMYCIN A)
Affinity DataIC50:  1.97nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50471297(CHEMBL424608)
Affinity DataIC50:  2.10nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
Riken (The Institute Of Physical And Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50093001((4aR,6S,7R,7aS)-7-[2-((S)-2-Amino-3-methyl-butyryl...)
Affinity DataIC50:  2.90nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50471293(CHEMBL83449)
Affinity DataIC50:  3.60nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
Riken (The Institute Of Physical And Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50093003((4aR,6S,7R,7aS)-7-[2-((2S,3S)-2-Amino-3-methyl-pen...)
Affinity DataIC50:  4.20nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50470911(CHEMBL122825)
Affinity DataIC50:  4.45nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureusMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50217841(REVEROMYCIN A)
Affinity DataIC50:  4.46nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50471295(CHEMBL312853)
Affinity DataIC50:  5.30nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50471291(CHEMBL83394)
Affinity DataIC50:  6nMAssay Description:Inhibition concentration against isoleucyl tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50470914(CHEMBL120343)
Affinity DataIC50:  6.67nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureus NCTC 3571More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50470913(CHEMBL120798)
Affinity DataIC50:  6.87nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureusMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50470912(CHEMBL120437)
Affinity DataIC50:  7.98nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureusMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093003((4aR,6S,7R,7aS)-7-[2-((2S,3S)-2-Amino-3-methyl-pen...)
Affinity DataIC50:  14nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366870(CHEMBL605376)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against Escherichia coli Isoleucyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075058(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  15nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
Riken (The Institute Of Physical And Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50093004((4aR,6S,7R,7aS)-7-[2-((2S,3S)-2-Amino-3-methyl-pen...)
Affinity DataIC50:  17nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479281(2,3-DIHYDROREVEROMYCIN A)
Affinity DataIC50:  17.5nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075061(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  20nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479274(4-HYDROXY REVEROMYCIN A)
Affinity DataIC50:  21.7nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
Riken (The Institute Of Physical And Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50093002((4aR,6S,7R,7aS)-7-[2-((2S,3S)-2-Amino-3-methyl-pen...)
Affinity DataIC50:  25nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075059(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  30nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075056(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  30nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075058(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  34nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479284(CHEMBL442945)
Affinity DataIC50:  36.9nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093001((4aR,6S,7R,7aS)-7-[2-((S)-2-Amino-3-methyl-butyryl...)
Affinity DataIC50:  37nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366862(CHEMBL605592)
Affinity DataIC50:  39nMAssay Description:Inhibitory activity against Escherichia coli Isoleucyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075056(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  40nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075056(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  40nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
Riken (The Institute Of Physical And Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217935(CHEMBL114859)
Affinity DataIC50:  44.4nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075070(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  45nMAssay Description:Compound tested for the inhibition of human Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075058(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  50nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075067(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: >54nMAssay Description:Compound tested for the inhibition of S. aureus Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093004((4aR,6S,7R,7aS)-7-[2-((2S,3S)-2-Amino-3-methyl-pen...)
Affinity DataIC50:  60nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
Riken (The Institute Of Physical And Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50093005((4aR,6S,7R,7aS)-7-[2-((S)-2-Amino-4-methyl-pentano...)
Affinity DataIC50:  68nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
Riken (The Institute Of Physical And Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217844(CHEMBL115953)
Affinity DataIC50:  74.4nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479277(2,3-DIHYDRO-5-EPIREVEROMYCIN A)
Affinity DataIC50:  88nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075069(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  90nMAssay Description:Compound tested for the inhibition of S. aureus Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50222902(CHEMBL1163069)
Affinity DataIC50:  98nMAssay Description:Inhibitory activity against Escherichia coli Isoleucyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075068(((2S,3S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid...)
Affinity DataIC50:  100nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075063(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  100nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075055(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  100nMAssay Description:Compound tested for the inhibition of S. aureus Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075063(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  100nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290689(9-{(E)-4-[(2S,3R,4R,5S)-5-(3-Chloro-propane-1-sulf...)
Affinity DataIC50:  100nMAssay Description:Compound was evaluated for inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50217935(CHEMBL114859)
Affinity DataIC50:  100nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075065(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  110nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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