Compile Data Set for Download or QSAR
maximum 50k data
Found 70 of ic50 data for polymerid = 50000338
TargetInterleukin-8(Homo sapiens (Human))
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LigandPNGBDBM277687(5-((2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-me...)
Affinity DataIC50:  2.80nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277693(2-((2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3...)
Affinity DataIC50:  2.90nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277686(5-((2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(m...)
Affinity DataIC50:  5.60nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277702(5-((2-(3-((4-((4-(3-(5-tert-Butyl)-2-methoxy-3-(me...)
Affinity DataIC50:  7.30nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277688(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl-2-methoxy-3-(...)
Affinity DataIC50:  7.30nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)
Affinity DataIC50:  8nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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LigandPNGBDBM277682(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy)-3...)
Affinity DataIC50:  8nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM50295276(2-(2-(2-fluorophenylamino)phenyl)acetic acid | CHE...)
Affinity DataIC50:  9nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50295266(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}propanoic a...)
Affinity DataIC50:  10nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM277694(US10072034, Example 20(a) | US10072034, Example 20...)
Affinity DataIC50:  10.4nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277685(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50:  11.7nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277683(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50:  11.7nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM50295267(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}propanamide...)
Affinity DataIC50:  12nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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LigandPNGBDBM50295281(2-(2-(2-fluorophenoxy)phenyl)acetic acid | CHEMBL2...)
Affinity DataIC50:  13nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50295268(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N-(methyls...)
Affinity DataIC50:  13nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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LigandPNGBDBM277696(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50:  14.4nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277701(5-((2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(m...)
Affinity DataIC50:  15.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277690(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-3-(ethylsulf...)
Affinity DataIC50:  16.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277689(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl-3-(ethylsulfo...)
Affinity DataIC50:  16.4nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277691(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl) isoxazol-3-y...)
Affinity DataIC50:  17.2nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277677(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy)-3...)
Affinity DataIC50:  17.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277697(1-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50:  18.1nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277680(2-(2-(2-(3-((4-((4-(3-(5-tert-Butyl-2-methoxy-3-(m...)
Affinity DataIC50:  18.1nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277694(US10072034, Example 20(a) | US10072034, Example 20...)
Affinity DataIC50:  19.1nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277679(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-(methoxy-d...)
Affinity DataIC50:  19.5nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM50295270(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N-(2-hydro...)
Affinity DataIC50:  20nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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LigandPNGBDBM50169048((R)-2-(3-Benzoyl-phenyl)-propionic acid | (R)-2-(3...)
Affinity DataIC50:  20nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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LigandPNGBDBM277703(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50:  20.6nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277681(2-(2-(2-(3-(4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(...)
Affinity DataIC50:  20.8nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277676(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50:  24.6nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM50295269(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N,N'-[3,3-...)
Affinity DataIC50:  25nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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LigandPNGBDBM50090679(2-(2-(2,5-dichlorophenylamino)phenyl)acetic acid |...)
Affinity DataIC50:  25nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM277700(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl-2-methoxy-3-(...)
Affinity DataIC50:  26.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277684(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-3-(dimethylp...)
Affinity DataIC50:  26.5nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277698(N-(3-(3-(4-((2-((3-(2-(2-(1H-Tetrazol-5-yl)methoxy...)
Affinity DataIC50:  29.2nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM277692(N-(5-(tert-Butl-2-methoxy-3-(3-(4-((2-((3-methoxy-...)
Affinity DataIC50:  29.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM50295283(2-[2-(2-Fluorophenoxy)phenyl]-N-(methylsulfonyl)ac...)
Affinity DataIC50:  50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50169044((-)-ibuprofen | (2R)-2-(4-isobutylphenyl)propanoic...)
Affinity DataIC50:  50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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LigandPNGBDBM277699(2-(2-(3-((4-((4-(3-(5-(tert-Buty-2-methoxy-3-(meth...)
Affinity DataIC50:  61.9nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM50295287(2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...)
Affinity DataIC50:  90nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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LigandPNGBDBM277678(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50:  115nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
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LigandPNGBDBM50295275(2-(2-(2-chlorophenylamino)phenyl)acetic acid | CHE...)
Affinity DataIC50:  400nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50295282(2-(2-(2-chlorophenoxy)phenyl)acetic acid | CHEMBL3...)
Affinity DataIC50:  500nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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LigandPNGBDBM50295274(2-(2-(2,6-dichloro-3-methylphenylamino)phenyl)acet...)
Affinity DataIC50:  500nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM59542((1-tosylbenzimidazol-2-yl)amine | 1-(4-methylpheny...)
Affinity DataIC50:  551nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
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LigandPNGBDBM59542((1-tosylbenzimidazol-2-yl)amine | 1-(4-methylpheny...)
Affinity DataIC50:  596nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
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LigandPNGBDBM50295271(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N-(2,6-dim...)
Affinity DataIC50:  600nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50295272(CHEMBL549975 | N-(tert-Butyl)-2-{2-[(2,6-dichlorop...)
Affinity DataIC50:  650nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50295273(3-(2-(2-(2,6-dichlorophenylamino)phenyl)propanamid...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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