Compile Data Set for Download or QSAR
maximum 50k data
Found 54 of ic50 data for polymerid = 50000558
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534100(WO2022081807, Example 207)
Affinity DataIC50:  5.65nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534020(6-(Azetidin-1-yl)-N-(5-tert-butyl-2-methoxybenzene...)
Affinity DataIC50:  5.67nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534117(WO2022081807, Example 224)
Affinity DataIC50:  9.82nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534118(6-(Azetidin-1-yl)-N-[(2-(benzyloxy)-5-(tert-butyl)...)
Affinity DataIC50:  9.82nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534006(N-(5-tert-butyl-2-ethoxybenzene-1-sulfonyl)-4-fluo...)
Affinity DataIC50:  12nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534121(WO2022081807, Example 228)
Affinity DataIC50:  13nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM533972(6-(Azetidin-1-yl)-4-fluoro-N-[3-(propan-2-yl)pyrid...)
Affinity DataIC50:  14nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534021(WO2022081807, Example 128)
Affinity DataIC50:  15nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534106(WO2022081807, Example 213)
Affinity DataIC50:  15nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534149(WO2022081842, Example 24)
Affinity DataIC50:  19nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534023(WO2022081807, Example 130)
Affinity DataIC50:  20nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534088(WO2022081807, Example 195)
Affinity DataIC50:  20nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534107(6-(azetidin-1-yl)-N-[2-(cyclopropylmethoxy)-5-isop...)
Affinity DataIC50:  20nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534045(WO2022081807, Example 152)
Affinity DataIC50:  20nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM533866(6-(Azetidin-1 -yl)-N-(2-ethoxy-6-methoxybenzene-1 ...)
Affinity DataIC50:  21nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534024(6-(Azetidin-1-yl)-N-[2-(cyclopropyloxy)benzene-1-s...)
Affinity DataIC50:  23nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534146(6-Cyclopropyl-4-fluoro-N-(2-methylquinoline-8-sulf...)
Affinity DataIC50:  23nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM50518832(CHEMBL4455897 | US10829446, Compound 36)
Affinity DataIC50:  28nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KAT6B (431 to end residues) expressed in baculovirus infected Sf9 insect cells using acetyl coe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534150(6-Cyclopropyl-N-(2-ethoxybenzene-1-sulfonyl)-4-flu...)
Affinity DataIC50:  28nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM50518832(CHEMBL4455897 | US10829446, Compound 36)
Affinity DataIC50:  28nMAssay Description:Inhibition of KAT6B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534122(6-(Azetidin-1-yl)-N-[(5-(tert-butyl)-2-isopropoxyp...)
Affinity DataIC50:  28nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534124(6-(Azetidin-1-yl)-N-((2-((2,2-difluorocyclopropyl)...)
Affinity DataIC50:  29nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534187(N-[(2-(Benzyloxy)-5-(tert-butyl)phenyl)sulfonyl]-6...)
Affinity DataIC50:  45nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534022(6-(Azetidin-1-yl)-4-fluoro-N-{2-[(propan-2-yl)oxy]...)
Affinity DataIC50:  52nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534145(4,6-Dimethyl-N-(2-methylquinoline-8-sulfonyl)-1-be...)
Affinity DataIC50:  53nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM533867(6-(Azetidin-1-yl)-N-(2-ethoxybenzene-1-sulfonyl)-4...)
Affinity DataIC50:  95nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534140(N-([1,1'-biphenyl]-2-sulfonyl)-6-cyclopropyl-1-ben...)
Affinity DataIC50:  104nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534131(WO2022081842, Example 7)
Affinity DataIC50:  114nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534148(N-([1,1'-biphenyl]-2-sulfonyl)-6-(prop-1-en-2-yl)-...)
Affinity DataIC50:  155nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534133(WO2022081842, Example 9)
Affinity DataIC50:  220nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534130(4,6-Dimethyl-N-(2'-methyl[1,1'-biphenyl]-2-sulfony...)
Affinity DataIC50:  245nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534019(WO2022081807, Example 126)
Affinity DataIC50:  285nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM533902(6-(Azetidin-1-yl)-N-([1,T-biphenyl]-2-sulfonyl)-1-...)
Affinity DataIC50:  292nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534135(N-(3'-chloro[1,1'-biphenyl]-2-sulfonyl)-4,6-dimeth...)
Affinity DataIC50:  299nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534136(4-Methoxy-6-methyl-N-(5-methyl[1,1'-biphenyl]-2-su...)
Affinity DataIC50:  372nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534182(N-(2-Ethoxybenzenesulfonyl)-6-(propan-2-yl)-1-benz...)
Affinity DataIC50:  538nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534181(N-{[1,1'-Biphenyl]-2-sulfonyl}-6-(propan-2-yl)-1-b...)
Affinity DataIC50:  667nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534134(N-([1,1'-biphenyl]-2-sulfonyl)-4-methoxy-6-methyl-...)
Affinity DataIC50:  1.12E+3nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534137(N-(2-Ethoxybenzene-1-sulfonyl)-4-methoxy-6-methyl-...)
Affinity DataIC50:  1.73E+3nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534196(N-(2-chlorobenzenesulfonyl)-6-(propan-2-yl)-1-benz...)
Affinity DataIC50:  1.78E+3nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534126(N-([1,1'-biphenyl]-2-sulfonyl)-6-methyl-1-benzofur...)
Affinity DataIC50:  2.22E+3nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534141(N-([1,1'-Biphenyl]-2-sulfonyl)-6-(difluoromethyl)-...)
Affinity DataIC50:  2.58E+3nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534151(N-([1,1'-biphenyl]-2-sulfonyl)-6-(2-methoxyethyl)-...)
Affinity DataIC50:  2.85E+3nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534183(N-(Benzenesulfonyl)-6-(propan-2-yl)-1-benzofuran-2...)
Affinity DataIC50:  3.94E+3nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534125(N-([1,1'-biphenyl]-2-sulfonyl)-6-(4-fluorophenyl)-...)
Affinity DataIC50:  4.79E+3nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534184(N-(2,4-Dichlorobenzenesulfonyl)-6-(propan-2-yl)-1-...)
Affinity DataIC50:  5.25E+3nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534152(N-([1,1'-biphenyl]-2-sulfonyl)-6-(butan-2-yl)-1-be...)
Affinity DataIC50:  9.21E+3nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534129(WO2022081842, Example 5)
Affinity DataIC50: >2.00E+4nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534132(N2-([1,1'-biphenyl]-2-sulfonyl)-N6,N6-dimethyl-1-b...)
Affinity DataIC50: >2.00E+4nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534128(N-([1,1'-biphenyl]-2-sulfonyl)-6-(pyridin-3-yl)-1-...)
Affinity DataIC50: >2.00E+4nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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