Compile Data Set for Download or QSAR
maximum 50k data
Found 575 of ic50 data for polymerid = 50003468
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086336(CHEMBL3426065)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human CD38 extracellular domain expressed in Pichia pastoris assessed as NAD hydrolysis by colorimetric-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086337(CHEMBL3426064)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human CD38 extracellular domain expressed in Pichia pastoris assessed as NAD hydrolysis by colorimetric-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086436(CHEMBL3426037)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human CD38 extracellular domain expressed in Pichia pastoris assessed as NAD hydrolysis by colorimetric-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086432(CHEMBL3426033)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human CD38 extracellular domain expressed in Pichia pastoris assessed as NAD hydrolysis by colorimetric-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50461132(CHEMBL4229241)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human CD38 extracellular domain expressed in Pichia pastoris using NAD as substrate pretreated for 30 mins followed by subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50600805(CHEMBL5178786)
Affinity DataIC50:  4nMAssay Description:Inhibition of human his tagged CD38 using N6-etheno-NAD as substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50580354(CHEMBL5076763)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of His-tagged human CD38 using etheno-NAD as substrate preincubated for 30 mins followed by substrate addition and further incubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086335(CHEMBL3426066)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human CD38 extracellular domain expressed in Pichia pastoris assessed as NAD hydrolysis by colorimetric-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50580351(CHEMBL5083478)
Affinity DataIC50:  5nMAssay Description:Inhibition of His-tagged human CD38 using etheno-NAD as substrate preincubated for 30 mins followed by substrate addition and further incubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086334(CHEMBL3426067)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of human CD38 extracellular domain expressed in Pichia pastoris assessed as NAD hydrolysis by colorimetric-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086431(CHEMBL3426032)
Affinity DataIC50:  6nMAssay Description:Inhibition of human CD38 extracellular domain expressed in Pichia pastoris assessed as NAD hydrolysis by colorimetric-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50580352(CHEMBL5091229)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of His-tagged human CD38 using etheno-NAD as substrate preincubated for 30 mins followed by substrate addition and further incubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50580353(CHEMBL5076855)
Affinity DataIC50:  7nMAssay Description:Inhibition of His-tagged human CD38 using etheno-NAD as substrate preincubated for 30 mins followed by substrate addition and further incubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086433(CHEMBL3426034)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of human CD38 extracellular domain expressed in Pichia pastoris assessed as NAD hydrolysis by colorimetric-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50461156(CHEMBL4225752)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of recombinant human CD38 extracellular domain expressed in Pichia pastoris using NAD as substrate pretreated for 30 mins followed by subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587934(US11535621, Example 184)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587935(US11535621, Example 185)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587940(US11535621, Example 190)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587942(N-((1S,4r)-4-((S)-1-hydroxyethyl)cyclohexyl)-5-(1H...)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587943(N-((1S,4r)-4-((S)-1-hydroxyethyl)cyclohexyl)-5-(1H...)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587951(US11535621, Example 200)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587956(US11535621, Example 205)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587961(US11535621, Example 210)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587962(US11535621, Example 211)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587963(US11535621, Example 212)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587965(US11535621, Example 214)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587966(US11535621, Example 215)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587968(US11535621, Example 217)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587970(US11535621, Example 219)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587975(US11535621, Example 224)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587976(US11535621, Example 225)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587979(US11535621, Example 228)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587980(US11535621, Example 229)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587982(US11535621, Example 231)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587987(US11535621, Example 236)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587988(US11535621, Example 237)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587989(US11535621, Example 238)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587990(US11535621, Example 239 | US11535621, Example 247)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587990(US11535621, Example 239 | US11535621, Example 247)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM588000(US11535621, Example 249)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM588011(US11535621, Example 260)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM588012(US11535621, Example 261)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM588014(US11535621, Example 263)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM588015(N-((1R,4r)-4-((R)-1-hydroxyethyl)cyclohexyl)-5-(1H...)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM588019(N-((1R,4r)-4-((R)-1-hydroxyethyl)cyclohexyl)-2-(1H...)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086434(CHEMBL3426035)
Affinity DataIC50:  10nMAssay Description:Inhibition of human CD38 extracellular domain expressed in Pichia pastoris assessed as NAD hydrolysis by colorimetric-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587766(US11535621, Example 27)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587768((S)-2-(1H-Imidazol-1-yl)-N-(tetrahydro-2H-pyran-3-...)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587779(2-(1H-Imidazol-1-yl)-N-((1s,4s)-4-(trifluoromethyl...)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM587780(2-(1H-Imidazol-1-yl)-N-((1s,4s)-4-(trifluoromethyl...)
Affinity DataIC50: <10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
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