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Compile Data Set for Download or QSAR

Found 22 hits of ic50 data for polymerid = 50006479   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM27497
PNG
(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)
Show SMILES CN(C)CC(=O)Nc1ccc2[nH]c(=O)c3ccccc3c2c1
Show InChI InChI=1S/C17H17N3O2/c1-20(2)10-16(21)18-11-7-8-15-14(9-11)12-5-3-4-6-13(12)17(22)19-15/h3-9H,10H2,1-2H3,(H,18,21)(H,19,22)
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n/an/a 25n/an/an/an/an/an/a



Queen's Center for Biomedical REsearch

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-hydroxyphenylpyruvate dioxygenase from pig liver; (observed value)


J Nat Prod 80: 2741-2750 (2017)


Article DOI: 10.1021/acs.jnatprod.7b00515
BindingDB Entry DOI: 10.7270/Q2GH9MHQ
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50242184
PNG
(SCALARADIAL | Scalaradial)
Show SMILES CC(=O)O[C@H]1C[C@@H]2[C@@]3(C)CCCC(C)(C)[C@@H]3CC[C@@]2(C)[C@@H]2CC=C(C=O)[C@H](C=O)[C@@]12C
Show InChI InChI=1S/C27H40O4/c1-17(30)31-23-14-22-25(4)12-7-11-24(2,3)20(25)10-13-26(22,5)21-9-8-18(15-28)19(16-29)27(21,23)6/h8,15-16,19-23H,7,9-14H2,1-6H3/t19-,20-,21-,22+,23-,25-,26-,27+/m0/s1
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n/an/a 210n/an/an/an/an/an/a



Queen's Center for Biomedical REsearch

Curated by ChEMBL


Assay Description
Inhibition of human FLAG-tagged TRPM2 expressed in HEK293 cells assessed as reduction in ADPR-induced intracellular calcium flux after 30 to 60 mins ...


J Nat Prod 80: 2741-2750 (2017)


Article DOI: 10.1021/acs.jnatprod.7b00515
BindingDB Entry DOI: 10.7270/Q2GH9MHQ
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50227083
PNG
(CHEMBL173443)
Show SMILES CCCCCc1ccc(\C=C\C(=O)Nc2ccccc2C(O)=O)cc1
Show InChI InChI=1S/C21H23NO3/c1-2-3-4-7-16-10-12-17(13-11-16)14-15-20(23)22-19-9-6-5-8-18(19)21(24)25/h5-6,8-15H,2-4,7H2,1H3,(H,22,23)(H,24,25)/b15-14+
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n/an/a 320n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human TRPM2 expressed in HEK293 cells assessed as reduction in ADPR-induced channel currents treated extracellularly after 60 secs by w...


Eur J Med Chem 152: 235-252 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.045
BindingDB Entry DOI: 10.7270/Q22J6FDS
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM27502
PNG
(3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoq...)
Show SMILES O=C1NCCc2c(OCCCCN3CCCCC3)cccc12
Show InChI InChI=1S/C18H26N2O2/c21-18-16-7-6-8-17(15(16)9-10-19-18)22-14-5-4-13-20-11-2-1-3-12-20/h6-8H,1-5,9-14H2,(H,19,21)
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n/an/a 600n/an/an/an/an/an/a



Queen's Center for Biomedical REsearch

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-hydroxyphenylpyruvate dioxygenase from pig liver; (observed value)


J Nat Prod 80: 2741-2750 (2017)


Article DOI: 10.1021/acs.jnatprod.7b00515
BindingDB Entry DOI: 10.7270/Q2GH9MHQ
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50278349
PNG
(2-(Diphenylboryloxy)Ethanamine | 2-Aminoethoxydiph...)
Show SMILES NCCOB(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C14H16BNO/c16-11-12-17-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10H,11-12,16H2
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n/an/a 1.00E+3n/an/an/an/an/an/a



Queen's Center for Biomedical REsearch

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)


J Nat Prod 80: 2741-2750 (2017)


Article DOI: 10.1021/acs.jnatprod.7b00515
BindingDB Entry DOI: 10.7270/Q2GH9MHQ
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50227083
PNG
(CHEMBL173443)
Show SMILES CCCCCc1ccc(\C=C\C(=O)Nc2ccccc2C(O)=O)cc1
Show InChI InChI=1S/C21H23NO3/c1-2-3-4-7-16-10-12-17(13-11-16)14-15-20(23)22-19-9-6-5-8-18(19)21(24)25/h5-6,8-15H,2-4,7H2,1H3,(H,22,23)(H,24,25)/b15-14+
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n/an/a 1.70E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human TRPM2 expressed in HEK293 cells assessed as reduction in H2O2-induced intracellular calcium flux after 30 mins by Fluo4-AM dye ba...


Eur J Med Chem 152: 235-252 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.045
BindingDB Entry DOI: 10.7270/Q22J6FDS
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50227083
PNG
(CHEMBL173443)
Show SMILES CCCCCc1ccc(\C=C\C(=O)Nc2ccccc2C(O)=O)cc1
Show InChI InChI=1S/C21H23NO3/c1-2-3-4-7-16-10-12-17(13-11-16)14-15-20(23)22-19-9-6-5-8-18(19)21(24)25/h5-6,8-15H,2-4,7H2,1H3,(H,22,23)(H,24,25)/b15-14+
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n/an/a 1.70E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human TRPM2 expressed in HEK293 cells assessed as reduction in ADPR-induced channel currents by whole cell patch clamp electrophysiolog...


Eur J Med Chem 152: 235-252 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.045
BindingDB Entry DOI: 10.7270/Q22J6FDS
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50405913
PNG
(CHEMBL4176916)
Show SMILES Cc1cc(Br)cc2C(=O)NC(Nc12)c1c[nH]nc1-c1cccc2ccccc12
Show InChI InChI=1S/C19H31NO4S/c1-2-11-20-18(21)13-25-12-15-14(16-9-10-17(15)24-16)7-5-3-4-6-8-19(22)23/h3,5,14-17H,2,4,6-13H2,1H3,(H,20,21)(H,22,23)/b5-3-
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n/an/a 3.70E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human TRPM2 expressed in HEK293 cells assessed as reduction in ADPR-induced channel currents treated extracellularly after 60 secs by w...


Eur J Med Chem 152: 235-252 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.045
BindingDB Entry DOI: 10.7270/Q22J6FDS
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50405912
PNG
(CHEMBL4159037)
Show SMILES Cc1cc(Cl)cc2C(=O)NC(Nc12)c1c[nH]nc1-c1cccc2ccccc12
Show InChI InChI=1S/C20H26O3S/c21-20(22)11-7-2-1-6-10-16-17(19-13-12-18(16)23-19)14-24-15-8-4-3-5-9-15/h1,3-6,8-9,16-19H,2,7,10-14H2,(H,21,22)/b6-1-
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n/an/a 4.00E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human TRPM2 expressed in HEK293 cells assessed as reduction in ADPR-induced channel currents treated extracellularly after 60 secs by w...


Eur J Med Chem 152: 235-252 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.045
BindingDB Entry DOI: 10.7270/Q22J6FDS
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50227083
PNG
(CHEMBL173443)
Show SMILES CCCCCc1ccc(\C=C\C(=O)Nc2ccccc2C(O)=O)cc1
Show InChI InChI=1S/C21H23NO3/c1-2-3-4-7-16-10-12-17(13-11-16)14-15-20(23)22-19-9-6-5-8-18(19)21(24)25/h5-6,8-15H,2-4,7H2,1H3,(H,22,23)(H,24,25)/b15-14+
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n/an/a 4.50E+3n/an/an/an/an/an/a



Queen's Center for Biomedical REsearch

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)


J Nat Prod 80: 2741-2750 (2017)


Article DOI: 10.1021/acs.jnatprod.7b00515
BindingDB Entry DOI: 10.7270/Q2GH9MHQ
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50405910
PNG
(CHEMBL4174768)
Show SMILES Cc1cc(Br)cc2C(=O)NC(Nc12)c1c[nH]nc1-c1ccccc1
Show InChI InChI=1S/C20H34O3S/c1-2-3-4-7-10-15-24-20-16(17-13-14-18(20)23-17)11-8-5-6-9-12-19(21)22/h5,8,16-18,20H,2-4,6-7,9-15H2,1H3,(H,21,22)/b8-5-
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n/an/a 4.60E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human TRPM2 expressed in HEK293 cells assessed as reduction in ADPR-induced channel currents treated extracellularly after 60 secs by w...


Eur J Med Chem 152: 235-252 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.045
BindingDB Entry DOI: 10.7270/Q22J6FDS
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50405911
PNG
(CHEMBL4167784)
Show SMILES Cc1cc(Cl)cc2C(=O)NC(Nc12)c1c[nH]nc1-c1ccccc1
Show InChI InChI=1S/C23H30O3S/c24-23(25)13-7-2-1-6-12-19-20(22-15-14-21(19)26-22)17-27-16-8-11-18-9-4-3-5-10-18/h1,3-6,8-11,19-22H,2,7,12-17H2,(H,24,25)/b6-1-,11-8+
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n/an/a 5.10E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human TRPM2 expressed in HEK293 cells assessed as reduction in ADPR-induced channel currents treated extracellularly after 60 secs by w...


Eur J Med Chem 152: 235-252 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.045
BindingDB Entry DOI: 10.7270/Q22J6FDS
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50450500
PNG
(CHEMBL4164465)
Show SMILES OC[C@]1(O)CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C18H15Cl2FN2O5S/c19-12-2-4-16(14(20)5-12)29(26,27)23-8-17(18(25,9-23)10-24)28-13-3-1-11(7-22)15(21)6-13/h1-6,17,24-25H,8-10H2/t17-,18+/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of TRPM2 (unknown origin)


J Med Chem 61: 9738-9755 (2018)


Article DOI: 10.1021/acs.jmedchem.8b01317
BindingDB Entry DOI: 10.7270/Q2CJ8H2P
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50446561
PNG
(CHEMBL3110215)
Show SMILES Nc1ncnc2n([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]4OC(O)[C@H](O)[C@@H]4O)[C@@H](O)[C@H]3O)c(nc12)-c1ccccc1
Show InChI InChI=1S/C21H27N5O14P2/c22-17-12-19(24-8-23-17)26(18(25-12)9-4-2-1-3-5-9)20-15(29)13(27)10(38-20)6-36-41(32,33)40-42(34,35)37-7-11-14(28)16(30)21(31)39-11/h1-5,8,10-11,13-16,20-21,27-31H,6-7H2,(H,32,33)(H,34,35)(H2,22,23,24)/t10-,11-,13-,14-,15-,16-,20-,21?/m1/s1
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n/an/a 1.10E+4n/an/an/an/an/an/a



University of Bath

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...


J Med Chem 56: 10079-102 (2013)


Article DOI: 10.1021/jm401497a
BindingDB Entry DOI: 10.7270/Q2CZ38P3
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50505550
PNG
(CHEMBL4439190)
Show SMILES OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(cc1Cl)C#N
Show InChI InChI=1S/C18H16Cl2N2O6S2/c19-13-2-4-14(5-3-13)29(25,26)17-9-22(10-18(17,24)11-23)30(27,28)16-6-1-12(8-21)7-15(16)20/h1-7,17,23-24H,9-11H2/t17-,18+/m0/s1
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n/an/a>3.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Antagonist activity at TRPM2 (unknown origin)


J Med Chem 61: 11209-11220 (2018)


Article DOI: 10.1021/acs.jmedchem.8b01344
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50446559
PNG
(CHEMBL3110213)
Show SMILES CC(=O)c1cccc(c1)-c1nc2c(N)ncnc2n1[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2OC(O)[C@H](O)[C@@H]2O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C23H29N5O15P2/c1-9(29)10-3-2-4-11(5-10)20-27-14-19(24)25-8-26-21(14)28(20)22-17(32)15(30)12(41-22)6-39-44(35,36)43-45(37,38)40-7-13-16(31)18(33)23(34)42-13/h2-5,8,12-13,15-18,22-23,30-34H,6-7H2,1H3,(H,35,36)(H,37,38)(H2,24,25,26)/t12-,13-,15-,16-,17-,18-,22-,23?/m1/s1
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n/an/a 4.90E+4n/an/an/an/an/an/a



University of Bath

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...


J Med Chem 56: 10079-102 (2013)


Article DOI: 10.1021/jm401497a
BindingDB Entry DOI: 10.7270/Q2CZ38P3
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50446560
PNG
(CHEMBL3110214)
Show SMILES Nc1ncnc2n([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]4OC(O)[C@H](O)[C@@H]4O)[C@@H](O)[C@H]3O)c(nc12)-c1ccsc1
Show InChI InChI=1S/C19H25N5O14P2S/c20-15-10-17(22-6-21-15)24(16(23-10)7-1-2-41-5-7)18-13(27)11(25)8(36-18)3-34-39(30,31)38-40(32,33)35-4-9-12(26)14(28)19(29)37-9/h1-2,5-6,8-9,11-14,18-19,25-29H,3-4H2,(H,30,31)(H,32,33)(H2,20,21,22)/t8-,9-,11-,12-,13-,14-,18-,19?/m1/s1
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n/an/a 5.10E+4n/an/an/an/an/an/a



University of Bath

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...


J Med Chem 56: 10079-102 (2013)


Article DOI: 10.1021/jm401497a
BindingDB Entry DOI: 10.7270/Q2CZ38P3
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM18137
PNG
(AMP | CHEMBL752 | [(2R,3S,4R,5R)-5-adenin-9-yl-3,4...)
Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
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n/an/a 7.00E+4n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of human TRPM2 assessed as reduction in ADPR-induced channel currents by whole cell patch clamp electrophysiology method


Eur J Med Chem 152: 235-252 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.045
BindingDB Entry DOI: 10.7270/Q22J6FDS
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50446558
PNG
(CHEMBL3110195)
Show SMILES Nc1ncnc2n(CCCCOP(O)(=O)OP(O)(=O)OC[C@H]3OC(O)[C@H](O)[C@@H]3O)cnc12
Show InChI InChI=1S/C14H23N5O11P2/c15-12-9-13(17-6-16-12)19(7-18-9)3-1-2-4-27-31(23,24)30-32(25,26)28-5-8-10(20)11(21)14(22)29-8/h6-8,10-11,14,20-22H,1-5H2,(H,23,24)(H,25,26)(H2,15,16,17)/t8-,10-,11-,14?/m1/s1
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n/an/a 1.00E+5n/an/an/an/an/an/a



University of Bath

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...


J Med Chem 56: 10079-102 (2013)


Article DOI: 10.1021/jm401497a
BindingDB Entry DOI: 10.7270/Q2CZ38P3
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50446557
PNG
(CHEMBL3110204)
Show SMILES NC(Cc1ccc(cc1)-c1nc2c(N)ncnc2n1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O)C(O)=O
Show InChI InChI=1S/C19H23N6O9P/c20-10(19(28)29)5-8-1-3-9(4-2-8)16-24-12-15(21)22-7-23-17(12)25(16)18-14(27)13(26)11(34-18)6-33-35(30,31)32/h1-4,7,10-11,13-14,18,26-27H,5-6,20H2,(H,28,29)(H2,21,22,23)(H2,30,31,32)/t10?,11-,13-,14-,18-/m1/s1
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n/an/a 1.00E+5n/an/an/an/an/an/a



University of Bath

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...


J Med Chem 56: 10079-102 (2013)


Article DOI: 10.1021/jm401497a
BindingDB Entry DOI: 10.7270/Q2CZ38P3
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50324670
PNG
(((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihyd...)
Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COS(=O)(=O)NC(=O)c2ccccc2O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C17H18N6O8S/c18-14-11-15(20-6-19-14)23(7-21-11)17-13(26)12(25)10(31-17)5-30-32(28,29)22-16(27)8-3-1-2-4-9(8)24/h1-4,6-7,10,12-13,17,24-26H,5H2,(H,22,27)(H2,18,19,20)/t10-,12-,13-,17-/m1/s1
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n/an/a 1.00E+5n/an/an/an/an/an/a



University of Bath

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...


J Med Chem 56: 10079-102 (2013)


Article DOI: 10.1021/jm401497a
BindingDB Entry DOI: 10.7270/Q2CZ38P3
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens (Human))
BDBM50446562
PNG
(CHEMBL3110216)
Show SMILES Nc1ncnc2n([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]4OC(O)[C@H](O)[C@@H]4O)[C@@H](O)[C@H]3O)c(Br)nc12
Show InChI InChI=1S/C15H22BrN5O14P2/c16-15-20-6-11(17)18-3-19-12(6)21(15)13-9(24)7(22)4(33-13)1-31-36(27,28)35-37(29,30)32-2-5-8(23)10(25)14(26)34-5/h3-5,7-10,13-14,22-26H,1-2H2,(H,27,28)(H,29,30)(H2,17,18,19)/t4-,5-,7-,8-,9-,10-,13-,14?/m1/s1
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n/an/a 3.00E+5n/an/an/an/an/an/a



University of Bath

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...


J Med Chem 56: 10079-102 (2013)


Article DOI: 10.1021/jm401497a
BindingDB Entry DOI: 10.7270/Q2CZ38P3
More data for this
Ligand-Target Pair