Compile Data Set for Download or QSAR
maximum 50k data
Found 40 of ic50 data for polymerid = 50007787
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM496959(cmdc.202100576, 23b)
Affinity DataIC50: <1nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM496960(cmdc.202100576, 23c)
Affinity DataIC50: <1nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM496962(cmdc.202100576, 23e)
Affinity DataIC50:  2nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM496961(cmdc.202100576, 23d)
Affinity DataIC50:  2nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM496963(cmdc.202100576, 23f)
Affinity DataIC50:  5nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM476929(SARS-CoV-2 3CLpro Inhibitors 3a | SARS-CoV-2 3CLpr...)
Affinity DataIC50:  49nMAssay Description:Cloning and Expression of the 3CL Protease of SARS-CoV-2 and FRET Enzyme Assays. The codon-optimized cDNA of full length of 3CLpro of SARS-CoV-2 (Gen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM476928(SARS-CoV-2 3CLpro Inhibitors 2a | SARS-CoV-2 3CLpr...)
Affinity DataIC50:  52nMAssay Description:Cloning and Expression of the 3CL Protease of SARS-CoV-2 and FRET Enzyme Assays. The codon-optimized cDNA of full length of 3CLpro of SARS-CoV-2 (Gen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM476949(SARS-CoV-2 3CLpro Inhibitors 3k | SARS-CoV-2 3CLpr...)
Affinity DataIC50:  53nMAssay Description:Cloning and Expression of the 3CL Protease of SARS-CoV-2 and FRET Enzyme Assays. The codon-optimized cDNA of full length of 3CLpro of SARS-CoV-2 (Gen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM476948(SARS-CoV-2 3CLpro Inhibitors 2k | SARS-CoV-2 3CLpr...)
Affinity DataIC50:  55nMAssay Description:Cloning and Expression of the 3CL Protease of SARS-CoV-2 and FRET Enzyme Assays. The codon-optimized cDNA of full length of 3CLpro of SARS-CoV-2 (Gen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM476939(SARS-CoV-2 3CLpro Inhibitors 3f)
Affinity DataIC50:  58nMAssay Description:Cloning and Expression of the 3CL Protease of SARS-CoV-2 and FRET Enzyme Assays. The codon-optimized cDNA of full length of 3CLpro of SARS-CoV-2 (Gen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM476938(SARS-CoV-2 3CLpro Inhibitors 2f)
Affinity DataIC50:  63nMAssay Description:Cloning and Expression of the 3CL Protease of SARS-CoV-2 and FRET Enzyme Assays. The codon-optimized cDNA of full length of 3CLpro of SARS-CoV-2 (Gen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM496949(GC868 | cmdc.202100576, 20b | cmdc.202100576, 20e)
Affinity DataIC50:  300nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50458469(CHEMBL4208240)
Affinity DataIC50:  400nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50458471(CHEMBL4204431)
Affinity DataIC50:  500nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM496950(GC867 | cmdc.202100576, 20c)
Affinity DataIC50:  500nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM496949(GC868 | cmdc.202100576, 20b | cmdc.202100576, 20e)
Affinity DataIC50:  600nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50458472(CHEMBL4217568)
Affinity DataIC50:  600nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50458463(CHEMBL4213159)
Affinity DataIC50:  600nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50458462(CHEMBL4214066)
Affinity DataIC50:  600nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM496951(GC861 | cmdc.202100576, 20d)
Affinity DataIC50:  600nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50458465(CHEMBL4203883)
Affinity DataIC50:  700nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM496953(GC833 | cmdc.202100576, 20f)
Affinity DataIC50:  700nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50458470(CHEMBL4209146)
Affinity DataIC50:  700nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50458473(CHEMBL4214471)
Affinity DataIC50:  700nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50458464(CHEMBL4202812)
Affinity DataIC50:  800nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50458466(CHEMBL4208764)
Affinity DataIC50:  900nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM429497(med.21724, Compound 170)
Affinity DataIC50:  6.00E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50458467(CHEMBL4212620)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50458468(CHEMBL4216101)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50523945(CHEMBL4475926)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of MERS-CoV papain-like protease using Z-Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM429499(med.21724, Compound 172)
Affinity DataIC50:  2.44E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50523946(ONO-1078)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of MERS-CoV papain-like protease using Z-Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM429498(med.21724, Compound 171)
Affinity DataIC50:  2.69E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50121025((E)-1-[2,4-Dihydroxy-5-(3-methyl-but-2-enyl)-pheny...)
Affinity DataIC50:  4.21E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50001908(1-(4-Nitro-phenyl)-piperazine | CHEMBL165012)
Affinity DataIC50:  7.16E+4nMAssay Description:Inhibition of MERS-CoV papain-like protease using Z-Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM429503(med.21724, Compound 176)
Affinity DataIC50:  1.13E+5nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50523947(CHEMBL4447423)
Affinity DataIC50:  1.37E+5nMAssay Description:Inhibition of MERS-CoV papain-like protease using Z-Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50523948(CHEBI:78878 | CHEMBL1743207)
Affinity DataIC50:  1.41E+5nMAssay Description:Inhibition of MERS-CoV papain-like protease using Z-Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50523949(4-Nitrocatechol | CHEBI:16318)
Affinity DataIC50:  1.45E+5nMAssay Description:Inhibition of MERS-CoV papain-like protease using Z-Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Experimental Drug Development Centre

LigandPNGBDBM50192743(3,4-Dihydroxybenzaldehyde | CHEBI:50205 | Protocat...)
Affinity DataIC50:  2.39E+5nMAssay Description:Inhibition of MERS-CoV papain-like protease using Z-Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed