Compile Data Set for Download or QSAR
maximum 50k data
Found 1178 of ic50 data for polymerid = 527
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50528416(CHEMBL4440965)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of N-terminal GST-tagged human AKT2 (120 to 481 residues) expressed in baculovirus infected Sf21 cells incubated for 1 hr in presence of A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126609(US8772283, 53)
Affinity DataIC50:  0.260nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126581(US8772283, 25)
Affinity DataIC50:  0.270nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126608(US8772283, 52)
Affinity DataIC50:  0.280nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126557(US8772283, 1)
Affinity DataIC50:  0.290nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126578(US8772283, 22)
Affinity DataIC50:  0.300nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126611(US8772283, 55)
Affinity DataIC50:  0.310nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126604(US8772283, 48)
Affinity DataIC50:  0.320nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126572(US8772283, 16)
Affinity DataIC50:  0.350nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126618(US8772283, 62)
Affinity DataIC50:  0.400nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126617(US8772283, 61)
Affinity DataIC50:  0.400nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126605(US8772283, 49)
Affinity DataIC50:  0.420nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126591(US8772283, 35)
Affinity DataIC50:  0.480nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126612(US8772283, 56)
Affinity DataIC50:  0.490nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126558(US8772283, 2)
Affinity DataIC50:  0.5nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM15131(5-indazolyl pyridine 3 | 5-{5-[(2S)-2-amino-3-(1H-...)
Affinity DataIC50:  0.5nMpH: 7.2 T: 2°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126615(US8772283, 59)
Affinity DataIC50:  0.530nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50528409(CHEMBL4441825)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of human Akt2 by mobile shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126600(US8772283, 44)
Affinity DataIC50:  0.550nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126616(US8772283, 60)
Affinity DataIC50:  0.570nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126574(US8772283, 18)
Affinity DataIC50:  0.600nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50528415(CHEMBL4457064)
Affinity DataIC50: <0.640nMAssay Description:Inhibition of human Akt2 by mobile shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126614(US8772283, 58)
Affinity DataIC50:  0.700nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126560(US8772283, 4)
Affinity DataIC50:  0.710nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126592(US8772283, 36)
Affinity DataIC50:  0.740nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126576(US8772283, 20)
Affinity DataIC50:  0.75nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126587(US8772283, 31)
Affinity DataIC50:  0.780nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126606(US8772283, 50)
Affinity DataIC50:  0.850nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126619(US8772283, 63)
Affinity DataIC50:  0.910nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126561(US8772283, 5)
Affinity DataIC50:  0.910nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126594(US8772283, 38)
Affinity DataIC50:  0.910nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126577(US8772283, 21)
Affinity DataIC50:  0.910nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126562(US8772283, 6)
Affinity DataIC50:  0.910nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126620(US8772283, 64)
Affinity DataIC50:  0.940nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126595(US8772283, 39)
Affinity DataIC50:  0.970nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126603(US8772283, 46)
Affinity DataIC50:  0.970nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126567(US8772283, 11)
Affinity DataIC50:  1nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50170284(GSK2141795 | GSK2141795C | Uprosertib)
Affinity DataIC50:  1nMAssay Description:Inhibition of human Akt2 by mobile shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126564(US8772283, 8)
Affinity DataIC50:  1nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126593(US8772283, 37)
Affinity DataIC50:  1.10nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126588(US8772283, 32)
Affinity DataIC50:  1.10nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126563(US8772283, 7)
Affinity DataIC50:  1.10nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126607(US8772283, 51)
Affinity DataIC50:  1.10nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126602(US8772283, 47)
Affinity DataIC50:  1.20nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50606346(CHEMBL5197007 | US20230321108, Isomer 4 of Example...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant AKT2 (120 to 481 end residues) (unknown origin) catalytic domain expressed in Sf21 cells using peptide substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50528416(CHEMBL4440965)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human Akt2 by mobile shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126559(US8772283, 3)
Affinity DataIC50:  1.20nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50606346(CHEMBL5197007 | US20230321108, Isomer 4 of Example...)
Affinity DataIC50:  1.20nMAssay Description:a) first, a compound stock solution (10 mM DMSO solution) was diluted with DMSO to obtain a 100 µM compound solution, the compound solution was dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126610(US8772283, 54)
Affinity DataIC50:  1.30nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM126566(US8772283, 10)
Affinity DataIC50:  1.40nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
In DepthDetails US Patent
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