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Found 927 of ic50 data for polymerid = 6311
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50:  70nMAssay Description:Inhibition of Cdc25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50:  80nMAssay Description:Inhibition of histidine-tagged full length human Cdc25B expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM41999(3-(3,4,5-trihydroxy-6-keto-xanthen-9-yl)propionic ...)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by spectrof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50208827(2,3-bis(2-hydroxyethylthio)naphthalene-1,4-dione |...)
Affinity DataIC50:  100nMAssay Description:Inhibition of GST tagged Cdc25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50:  110nMAssay Description:Inhibition of histidine-tagged human recombinant Cdc25B catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50317356(3-(3-stearoyl-1H-pyrazole-5-carboxamido)thiophene-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50177318(2-(4-(7-(4-tetradecylbenzoyl)cyclopenta[d][1,2]oxa...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against cdc25B phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50208827(2,3-bis(2-hydroxyethylthio)naphthalene-1,4-dione |...)
Affinity DataIC50:  125nMAssay Description:Inhibition of human Cdc25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50317355(2-(3-stearoyl-1H-pyrazole-5-carboxamido)benzoic ac...)
Affinity DataIC50:  160nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50317365(5-(4-chlorophenyl)-3-stearoylpyrrolo[3,4-c]pyrazol...)
Affinity DataIC50:  170nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM124256((3S,3aR,4S,7aS)-4-acetyl-7-dodecyl-3-methyl-1-oxo-...)
Affinity DataIC50:  200nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50297586(CHEMBL557129 | N-(1-benzyl-3-cyano-1H-pyrrolo[3,2-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of GST-fused Cdc25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human recombinant GST-tagged CDC25B expressed in Escherichia coli BL21 (DE3) using pNPP as substrate measured for 2 mins by colorimetri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50106497(6-Chloro-7-(2-morpholin-4-yl-ethylamino)-quinoline...)
Affinity DataIC50:  210nMAssay Description:Inhibitory activity against recombinant human cell division cycle 25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50297585(CHEMBL557673 | N-(1-benzyl-1H-pyrrolo[3,2-b]quinox...)
Affinity DataIC50:  210nMAssay Description:Inhibition of GST-fused Cdc25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM124255((3S,3aR,4S,7R,7aS)-4-acetyl-7-dodecyl-3-methyl-1-o...)
Affinity DataIC50:  220nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM31040(1-Ethyl-6-methyl-3-phenyl-1H-pyrimido[5,4-e][1,2,4...)
Affinity DataIC50:  223nMAssay Description:The Cdc25B Phosphatase Secondary Selectivity Assay has been developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) part...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50317352(5-phenyl-3-stearoylpyrrolo[3,4-c]pyrazole-4,6(1H,5...)
Affinity DataIC50:  230nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50317364(5-(3-chlorophenyl)-3-stearoylpyrrolo[3,4-c]pyrazol...)
Affinity DataIC50:  240nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50317366(5-(2-bromophenyl)-3-stearoylpyrrolo[3,4-c]pyrazole...)
Affinity DataIC50:  250nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50504361(CHEMBL4452484)
Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant Cdc25B (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50341995(5-(2-(dimethylamino)ethylamino)-2,6-dimethylbenzo[...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human Cdc25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50099736(4-Ethoxy-[1,2]naphthoquinone | 4-ethoxynaphthalene...)
Affinity DataIC50:  270nMAssay Description:Inhibition of histidine-tagged human recombinant Cdc25B catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50106505(6-Chloro-7-(indan-1-ylamino)-quinoline-5,8-dione |...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against recombinant human cell division cycle 25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50317382(5-(naphthalen-1-yl)-3-stearoylpyrrolo[3,4-c]pyrazo...)
Affinity DataIC50:  310nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50317376(3-stearoyl-5-(2-(trifluoromethyl)phenyl)pyrrolo[3,...)
Affinity DataIC50:  320nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50512278(CHEMBL4475724)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant GST-tagged CDC25B expressed in Escherichia coli BL21 (DE3) using pNPP as substrate measured for 2 mins by colorimetri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50317380(CHEMBL1098821 | methyl 3-(4,6-dioxo-3-stearoylpyrr...)
Affinity DataIC50:  340nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM32102(1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,...)
Affinity DataIC50:  349nMAssay Description:The Cdc25B Phosphatase HTS dose response confirmation has been developed to confirm actives identified in the Cdc25B HTS AID 368, screened at the Uni...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50106491(5-Amino-6-(7-amino-6-methoxy-5,8-dioxo-5,8-dihydro...)
Affinity DataIC50:  370nMAssay Description:Inhibitory activity against recombinant human cell division cycle 25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50512277(CHEMBL4445615)
Affinity DataIC50:  380nMAssay Description:Inhibition of human recombinant GST-tagged CDC25B expressed in Escherichia coli BL21 (DE3) using pNPP as substrate measured for 2 mins by colorimetri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM32102(1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,...)
Affinity DataIC50:  396nMAssay Description:The MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment Cdc25B Dose Response Selectivity Assay has been developed to evaluate the PT...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50033731((R)-5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl...)
Affinity DataIC50:  400nMAssay Description:Inhibition of recombinant Cdc25B (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50261252(CHEMBL511236 | [((R)-4-Hexadecanoyl-3-hydroxy-5-ox...)
Affinity DataIC50:  400nMAssay Description:Inhibition of cdc25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM31040(1-Ethyl-6-methyl-3-phenyl-1H-pyrimido[5,4-e][1,2,4...)
Affinity DataIC50:  400nMAssay Description:The Cdc25B Phosphatase HTS dose response confirmation has been developed to confirm actives identified in the Cdc25B HTS AID 368, screened at the Uni...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50317359(5-(4-nitrophenyl)-3-stearoylpyrrolo[3,4-c]pyrazole...)
Affinity DataIC50:  400nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50317374(CHEMBL1098791 | methyl 2-(4,6-dioxo-3-stearoylpyrr...)
Affinity DataIC50:  410nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM31044(1-Ethyl-6-methyl-3-thiophen-2-yl-1H-pyrimido[5,4-e...)
Affinity DataIC50:  421nMAssay Description:The Cdc25B Phosphatase probe assessment dose response reproducibility assay has been developed to re-confirm actives that were identified in the Cdc2...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50106503(6-Chloro-7-(2-morpholin-4-yl-ethylamino)-phthalazi...)
Affinity DataIC50:  430nMAssay Description:Inhibitory activity against recombinant human cell division cycle 25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM31040(1-Ethyl-6-methyl-3-phenyl-1H-pyrimido[5,4-e][1,2,4...)
Affinity DataIC50:  447nMAssay Description:The MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment Cdc25B Dose Response Selectivity Assay has been developed to evaluate the PT...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50106493(7-[2-(4-Hydroxy-3-methoxy-phenyl)-ethylamino]-quin...)
Affinity DataIC50:  450nMAssay Description:Inhibitory activity against recombinant human cell division cycle 25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50317361(5-(2-fluorophenyl)-3-stearoylpyrrolo[3,4-c]pyrazol...)
Affinity DataIC50:  450nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50512272(CHEMBL4450252)
Affinity DataIC50:  490nMAssay Description:Inhibition of human recombinant GST-tagged CDC25B expressed in Escherichia coli BL21 (DE3) using pNPP as substrate measured for 2 mins by colorimetri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50317375(CHEMBL1098792 | methyl 4-(4,6-dioxo-3-stearoylpyrr...)
Affinity DataIC50:  490nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM31040(1-Ethyl-6-methyl-3-phenyl-1H-pyrimido[5,4-e][1,2,4...)
Affinity DataIC50:  493nMAssay Description:The Cdc25B Phosphatase probe assessment dose response reproducibility assay has been developed to re-confirm actives that were identified in the Cdc2...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50317358(5-(4-nitrophenyl)-3-tetradecanoylpyrrolo[3,4-c]pyr...)
Affinity DataIC50:  500nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM34163(3-Amino-7-benzyl-1-thioxo-5,6,7,8-tetrahydro-1H-th...)
Affinity DataIC50:  502nMAssay Description:The Cdc25B Phosphatase probe assessment dose response reproducibility assay has been developed to re-confirm actives that were identified in the Cdc2...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM80759(7-[(1-hydroxy-1-phenylpropan-2-yl)amino]quinoline-...)
Affinity DataIC50:  510nMAssay Description:Inhibitory activity against recombinant human cell division cycle 25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50317369(5-(3-methoxyphenyl)-3-stearoylpyrrolo[3,4-c]pyrazo...)
Affinity DataIC50:  520nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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