Compile Data Set for Download or QSAR
maximum 50k data
Found 19 of ic50 data for polymerid = 8378
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM199123(N-(4-(1-(4,6-bis((4-hydroxyphenyl)amino)-1,3,5-tri...)
Affinity DataIC50:  8.12nMpH: 7.5 T: 2°CAssay Description:where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM199124(N-(4-(1-(4,6-bis((4-methoxyphenyl)amino)-1,3,5-tri...)
Affinity DataIC50:  18.6nMpH: 7.5 T: 2°CAssay Description:where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM199128(N-(4-(1-(4,6-dimorpholino-1,3,5-triazin-2-yl)-5-(4...)
Affinity DataIC50:  42.3nMpH: 7.5 T: 2°CAssay Description:where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM199127(N-(4-(1-(4,6-di(piperazin-1-yl)-1,3,5-triazin-2-yl...)
Affinity DataIC50:  55.3nMpH: 7.5 T: 2°CAssay Description:where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM199125(N-(4-(1-(4,6-bis(o-tolylamino)-1,3,5-triazin-2-yl)...)
Affinity DataIC50:  67.1nMpH: 7.5 T: 2°CAssay Description:where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM199126(N-(4-(1-(4,6-bis((4-nitrophenyl)amino)-1,3,5-triaz...)
Affinity DataIC50:  76.6nMpH: 7.5 T: 2°CAssay Description:where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM199122(N-(4-(1-(4,6-bis(phenylamino)-1,3,5-triazin-2-yl)-...)
Affinity DataIC50:  123nMpH: 7.5 T: 2°CAssay Description:where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM199121(N-(4-(1-(4,6-bis((3-aminopropyl)amino)-1,3,5-triaz...)
Affinity DataIC50:  189nMpH: 7.5 T: 2°CAssay Description:where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM199120(N-(4-(1-(4,6-bis(ethylamino)-1,3,5-triazin-2-yl)-5...)
Affinity DataIC50:  332nMpH: 7.5 T: 2°CAssay Description:where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM199119(N-(4-(1-(4,6-bis(methylamino)-1,3,5-triazin-2-yl)-...)
Affinity DataIC50:  666nMpH: 7.5 T: 2°CAssay Description:where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM50310832(CHEMBL1080779 | Clinopodic acid C)
Affinity DataIC50:  3.26E+3nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM50250808(CHEMBL518243 | lithospermic acid)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM50133496((2R)-3-(3,4-dihydroxyphenyl)-2-[(2E)-3-(3,4-dihydr...)
Affinity DataIC50:  2.72E+4nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM50210054((R,E)-3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropa...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM50310831(CHEMBL1079231 | Clinopodic acid A)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM50310830(CHEMBL1080778 | Clinopodic acid B)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM50310828(CHEMBL1079356 | clinopodic acid F)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM50310827(CHEMBL1079357 | clinopodic acid H)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Zhejiang Hospital

LigandPNGBDBM50310829(CHEMBL1081512 | clinopodic acid E)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed