Affinity DataKd: 0.0100nMAssay Description:Binding affinity to Aurora A (unknown origin) after 45 mins by fluorescence-based thermal stability shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.0100nMAssay Description:Binding affinity to Aurora A (unknown origin) after 45 mins by fluorescence-based thermal stability shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.200nMT: 2°CAssay Description:A stock solution was prepared containing complex of Aurora A and Compound I (final total concentrations of 6nM and 5nM, respectively). Separately, se...More data for this Ligand-Target Pair
Affinity DataKd: 0.273nMT: 2°CAssay Description:A stock solution was prepared containing complex of Aurora A and Compound I (final total concentrations of 6nM and 5nM, respectively). Separately, se...More data for this Ligand-Target Pair
Affinity DataKd: 0.440nMAssay Description:Binding affinity to purified recombinant full-length Aurora A (unknown origin) by fluorescence polarisation/anisotropy based equilibrium binding assa...More data for this Ligand-Target Pair
Affinity DataKd: 0.501nMAssay Description:Binding affinity to DNA-tagged human partial length AURKA expressed in mammalian expression system by qPCR methodMore data for this Ligand-Target Pair
Affinity DataKd: 0.730nMAssay Description:Binding affinity to purified recombinant full-length Aurora A (unknown origin) by fluorescence polarisation/anisotropy based equilibrium binding assa...More data for this Ligand-Target Pair
Affinity DataKd: 1.30nMAssay Description:Binding affinity to AURKA (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 1.90nMAssay Description:Binding affinity to purified recombinant full-length Aurora A (unknown origin) by fluorescence polarisation/anisotropy based equilibrium binding assa...More data for this Ligand-Target Pair
Affinity DataKd: 2.20nMAssay Description:Binding affinity to purified recombinant full-length Aurora A (unknown origin) by fluorescence polarisation/anisotropy based equilibrium binding assa...More data for this Ligand-Target Pair
Affinity DataKd: 2.5nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.5nMAssay Description:Binding affinity to purified recombinant full-length Aurora A (unknown origin) by fluorescence polarisation/anisotropy based equilibrium binding assa...More data for this Ligand-Target Pair
Affinity DataKd: 2.80nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.90nMAssay Description:Binding constant for AURKA kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Binding affinity to Aurora A kinase catalytic domain by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.10nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 4.10nMAssay Description:Binding constant for AURKA kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 4.20nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.5nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:Binding affinity to Aurora A kinase catalytic domain by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:Binding affinity to human Aurora A kinase expressed in Escherichia coli BL21 cells incubated for 1 hr by active site directed binding competition ass...More data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:Binding affinity to Aurora A kinase catalytic domain by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.10nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.20nMT: 2°CAssay Description:A stock solution was prepared containing complex of Aurora A and Compound I (final total concentrations of 6nM and 5nM, respectively). Separately, se...More data for this Ligand-Target Pair
Affinity DataKd: 5.60nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.70nMAssay Description:Binding affinity to purified recombinant full-length Aurora A (unknown origin) by fluorescence polarisation/anisotropy based equilibrium binding assa...More data for this Ligand-Target Pair
Affinity DataKd: 5.80nMAssay Description:Binding affinity to Aurora kinase A catalytic domain by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 6nMAssay Description:Binding affinity to Aurora A kinase catalytic domain by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 6.10nMAssay Description:Binding affinity to purified recombinant full-length Aurora A (unknown origin) by fluorescence polarisation/anisotropy based equilibrium binding assa...More data for this Ligand-Target Pair
Affinity DataKd: 6.30nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
Affinity DataKd: 6.30nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
Affinity DataKd: 6.40nMAssay Description:Inhibition of Aurora kinase A autophosphorylation in human HEK293 cells after 2 hrs by phosphor antibody readout assayMore data for this Ligand-Target Pair
Affinity DataKd: 6.5nMAssay Description:Binding constant for AURKA kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 6.5nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 6.5nMAssay Description:Binding affinity to purified recombinant full-length Aurora A (unknown origin) by fluorescence polarisation/anisotropy based equilibrium binding assa...More data for this Ligand-Target Pair
Affinity DataKd: 6.5nMAssay Description:Binding constant for AURKA kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 7nMAssay Description:Binding affinity to Aurora A kinase catalytic domain by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 7nMAssay Description:Binding affinity to Aurora A kinase catalytic domain by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 7nMAssay Description:Binding affinity to Aurora A kinase catalytic domain by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 7nMAssay Description:Binding affinity to Aurora A kinase catalytic domain by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 7.5nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
Affinity DataKd: 7.5nMAssay Description:The kinase selectivity was assessed by profiling Example 1 in a 442-kinase panel (386 non-mutant kinases) at a concentration of 1 μM using the K...More data for this Ligand-Target Pair
Affinity DataKd: 8nMAssay Description:Binding affinity to Aurora A kinase catalytic domain by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 8nMAssay Description:Binding affinity to Aurora A kinase catalytic domain by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 8nMAssay Description:Binding affinity to Aurora A kinase catalytic domain by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 8nMAssay Description:Binding affinity to Aurora A kinase catalytic domain by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 8.80nMAssay Description:Binding affinity to Aurora kinase A catalytic domain by competition binding assayMore data for this Ligand-Target Pair