Affinity DataKd: 0.00000100nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparation at a duration of 3hMore data for this Ligand-Target Pair
Affinity DataKd: 0.00000100nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparation at a duration of 40 minMore data for this Ligand-Target Pair
Affinity DataKd: 0.00000100nMAssay Description:In vivo inihibition of Beta-1 adrenergic receptor in guinea pig right atria after 40 minMore data for this Ligand-Target Pair
Affinity DataKd: 0.00000100nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparation at a duration of 3hMore data for this Ligand-Target Pair
Affinity DataKd: 0.0000100nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparation at a duration of 3hMore data for this Ligand-Target Pair
Affinity DataKd: 0.0000100nMAssay Description:In vivo inihibition of Beta-1 adrenergic receptor in guinea pig right atria after 40 minMore data for this Ligand-Target Pair
Affinity DataKd: 0.00100nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparation at a duration of 40 minMore data for this Ligand-Target Pair
Affinity DataKd: 0.00100nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparation at a duration of 40 minMore data for this Ligand-Target Pair
Affinity DataKd: 0.00100nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparation at a duration of 3hMore data for this Ligand-Target Pair
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataKd: 0.0631nMAssay Description:Antagonist activity at rat beta-1 adrenergic receptor W134A mutant expressed in CHO cellsMore data for this Ligand-Target Pair
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataKd: 0.0631nMAssay Description:Antagonist activity at rat wild type beta-1 adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataKd: 0.0631nMAssay Description:Antagonist activity at rat beta-1 adrenergic receptor S190A mutant expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKd: 0.0750nMAssay Description:Displacement of [3H]CGP12177 from human beta-1 adrenergic receptor stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Affinity DataKd: 0.0750nMAssay Description:Displacement of [3H]CGP12177 from human beta-1 adrenergic receptor stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Affinity DataKd: 0.0750nMAssay Description:Displacement of [3H]CGP12177 from human beta-1 adrenergic receptor stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Affinity DataKd: 0.0750nMAssay Description:Displacement of [3H]CGP12177 from human beta-1 adrenergic receptor stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation cou...More data for this Ligand-Target Pair
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataKd: 0.0794nMAssay Description:Antagonist activity at rat beta-1 adrenergic receptor Y356F mutant expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKd: 0.100nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparation at a duration of 3hMore data for this Ligand-Target Pair
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
The University Of Melbourne
Curated by ChEMBL
The University Of Melbourne
Curated by ChEMBL
Affinity DataKd: 0.316nMAssay Description:Antagonist activity at rat beta-1 adrenergic receptor Y356A mutant expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKd: 0.331nMAssay Description:Antagonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...More data for this Ligand-Target Pair
Affinity DataKd: 0.331nMAssay Description:Antagonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...More data for this Ligand-Target Pair
Affinity DataKd: 0.363nMAssay Description:In vitro beta-1 adrenergic receptor activity was determined via inhibition of the positive chronotropic actions of isoproterenol in isolated guinea p...More data for this Ligand-Target Pair
Affinity DataKd: 0.380nMAssay Description:Binding affinity to beta-1 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKd: 0.620nMpH: 7.4 T: 2°CAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
Affinity DataKd: 0.851nMAssay Description:In vitro beta-1 adrenergic receptor activity was determined via inhibition of the positive chronotropic actions of isoproterenol in isolated guinea p...More data for this Ligand-Target Pair
Affinity DataKd: 0.851nMAssay Description:In vitro beta-1 adrenergic receptor activity was determined via inhibition of the positive chronotropic actions of isoproterenol in isolated guinea p...More data for this Ligand-Target Pair
Affinity DataKd: 0.891nMAssay Description:In vitro beta-1 adrenergic receptor activity was determined via inhibition of the positive chronotropic actions of isoproterenol in isolated guinea p...More data for this Ligand-Target Pair
Affinity DataKd: 0.977nMAssay Description:Displacement of [3H](-)CGP12177 from human beta1-AR expressed in CHOK1 cells after 2 hrs by TopCount microscintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:Antagonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...More data for this Ligand-Target Pair
Affinity DataKd: 1.10nMAssay Description:Displacement of [3H](-)CGP12177 from human beta1-AR expressed in CHOK1 cells after 2 hrs by TopCount microscintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKd: 1.20nMAssay Description:In vitro beta-1 adrenergic receptor activity was determined via inhibition of the positive chronotropic actions of isoproterenol in isolated guinea p...More data for this Ligand-Target Pair
Affinity DataKd: 1.24nMpH: 7.4 T: 2°CAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
Affinity DataKd: 1.5nMAssay Description:Antagonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...More data for this Ligand-Target Pair
Affinity DataKd: 1.60nMpH: 7.4 T: 2°CAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
Affinity DataKd: 1.60nMAssay Description:Displacement of [3H]-CGP12177 from human beta1 adrenoceptor expressed in CHOK1 cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.60nMAssay Description:In vitro beta-1 adrenergic receptor activity was determined via inhibition of the positive chronotropic actions of isoproterenol in isolated guinea p...More data for this Ligand-Target Pair
Affinity DataKd: 1.60nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparationMore data for this Ligand-Target Pair
Affinity DataKd: 1.70nMAssay Description:In vitro beta-1 adrenergic receptor activity was determined via inhibition of the positive chronotropic actions of isoproterenol in isolated guinea p...More data for this Ligand-Target Pair
Affinity DataKd: 1.70nMAssay Description:Antagonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...More data for this Ligand-Target Pair
Affinity DataKd: 1.70nMAssay Description:In vitro beta-1 adrenergic receptor activity was determined via inhibition of the positive chronotropic actions of isoproterenol in isolated guinea p...More data for this Ligand-Target Pair
Affinity DataKd: 1.76nMpH: 7.4 T: 2°CAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
Affinity DataKd: 1.80nMAssay Description:Antagonist activity at human beta-1 adrenergic receptor site 1 expressed in cimeterol-stimulated CHO-K1 cells assessed as CRE-SPAP level by fluoresce...More data for this Ligand-Target Pair
Affinity DataKd: 1.80nMAssay Description:Displacement of [3H]-CGP12177 from human beta1 adrenoceptor expressed in CHOK1 cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.90nMAssay Description:In vitro beta-1 adrenergic receptor activity was determined via inhibition of the positive chronotropic actions of isoproterenol in isolated guinea p...More data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:In vitro ability to block beta-1 adrenergic receptor in guinea pig right atria.More data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:Antagonist activity of compound against Beta-1 adrenergic receptor in isolated guinea pig left atriaMore data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparationMore data for this Ligand-Target Pair
Affinity DataKd: 2.40nMAssay Description:Antagonism of the isoprenaline-induced positive chronotropic effect on the atria of guinea pigMore data for this Ligand-Target Pair
Affinity DataKd: 2.40nMAssay Description:Antagonist activity at human beta-1 adrenergic receptor site 1 expressed in cimeterol-stimulated CHO-K1 cells assessed as CRE-SPAP level by fluoresce...More data for this Ligand-Target Pair
Affinity DataKd: 2.40nMAssay Description:Beta-1 adrenergic receptor blocking activity in atria of guinea pig.More data for this Ligand-Target Pair