Compile Data Set for Download or QSAR
maximum 50k data
Found 113 of kd data for polymerid = 3579
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50481603(CHEMBL607562)
Affinity DataKd:  0.210nMAssay Description:Displacement of [125I-N-Methyl-4-(4-bromoanilino)phthalimide from beta-amyloid plaques isolated from Alzheimer's disease patient brainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50497728(CHEMBL3314344)
Affinity DataKd:  0.560nMAssay Description:Binding affinity to amyloid beta42 (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598562(CHEMBL5207165)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to amyloid beta (1 to 42) (unknown origin) aggregatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50173647((E)-4-(4-(methylamino)styryl)phenol | 4-(4-(methyl...)
Affinity DataKd:  2.40nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598552(CHEMBL5186511)
Affinity DataKd:  3.20nMAssay Description:Binding affinity to human amyloid beta (1 to 42) monomer measured by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598552(CHEMBL5186511)
Affinity DataKd:  3.80nMAssay Description:Binding affinity to human amyloid beta (1 to 42) oligomer measured by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50485997(CHEMBL2203379)
Affinity DataKd:  4.5nMAssay Description:Displacement of [3H]DMAB from amyloid beta plaque in cortex homogenate isolated from Alzheimer disease patient after 90 mins by scintillation countin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50486005(CHEMBL2203394)
Affinity DataKd:  6.40nMAssay Description:Displacement of [3H]DMAB from amyloid beta plaque in cortex homogenate isolated from Alzheimer disease patient after 90 mins by scintillation countin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50129793(2-(4''-methylaminophenyl)-6-hydroxybenzothiazole |...)
Affinity DataKd:  7.20nMAssay Description:Binding affinity to beta amyloid plaque in human Alzheimer's disease brain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50481119(AZD-2184 | CHEMBL570378)
Affinity DataKd:  8.40nMAssay Description:Displacement of [3H]PIB from human amyloid beta (1 to 40) fibrils after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50485994(CHEMBL2203385)
Affinity DataKd:  9.60nMAssay Description:Displacement of [3H]DMAB from amyloid beta plaque in cortex homogenate isolated from Alzheimer disease patient after 90 mins by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598567(CHEMBL5199963)
Affinity DataKd:  15nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) measured by competitive radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598551(CHEMBL5169704)
Affinity DataKd:  16nMAssay Description:Binding affinity to human amyloid beta (1 to 42) oligomer measured by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598566(CHEMBL5192359)
Affinity DataKd:  24nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 40) (unknown origin) measured by competitive radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598551(CHEMBL5169704)
Affinity DataKd:  24nMAssay Description:Binding affinity to human amyloid beta (1 to 42) monomer measured by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50515566(CHEMBL4475538)
Affinity DataKd:  25nMAssay Description:Binding affinity to amyloid beta 1 to 42 (unknown origin) in PBS buffer at pH 7.4 assessed as binding constant by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598556(CHEMBL5174620)
Affinity DataKd:  27nMAssay Description:Binding affinity to amyloid beta (1 to 42) (unknown origin) aggregatesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598551(CHEMBL5169704)
Affinity DataKd:  27nMAssay Description:Binding affinity to human amyloid beta (1 to 42) aggregates measured by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50515565(CHEMBL4453231)
Affinity DataKd:  35nMAssay Description:Binding affinity to amyloid beta 1 to 42 (unknown origin) in PBS buffer at pH 7.4 assessed as binding constant by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598552(CHEMBL5186511)
Affinity DataKd:  38nMAssay Description:Binding affinity to human amyloid beta (1 to 40) aggregates measured by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598536(CHEMBL5183943)
Affinity DataKd:  39nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) fibrilsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50484502(CHEMBL1926768)
Affinity DataKd:  42nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598550(CHEMBL5183307)
Affinity DataKd:  46nMAssay Description:Binding affinity to amyloid beta (1 to 42) (unknown origin) monomerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50515568(CHEMBL4570231)
Affinity DataKd:  46nMAssay Description:Binding affinity to amyloid beta 1 to 42 (unknown origin) in PBS buffer at pH 7.4 assessed as binding constant by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50490495(CHEMBL2326893)
Affinity DataKd:  48nMAssay Description:Binding affinity to amyloid beta aggregate (unknown origin) by centrifugation methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598553(CHEMBL5207355)
Affinity DataKd:  52nMAssay Description:Binding affinity to human amyloid beta (1 to 40) aggregates measured by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598553(CHEMBL5207355)
Affinity DataKd:  69nMAssay Description:Binding affinity to human amyloid beta (1 to 42) oligomer measured by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50515567(CHEMBL4524664)
Affinity DataKd:  77nMAssay Description:Binding affinity to amyloid beta 1 to 42 (unknown origin) in PBS buffer at pH 7.4 assessed as binding constant by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598553(CHEMBL5207355)
Affinity DataKd:  86nMAssay Description:Binding affinity to human amyloid beta (1 to 40) monomer measured by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50484498(CHEMBL1926769)
Affinity DataKd:  91nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598550(CHEMBL5183307)
Affinity DataKd:  106nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) monomerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598564(CHEMBL5193352)
Affinity DataKd:  106nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) measured by competitive radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598549(CHEMBL594574)
Affinity DataKd:  110nMAssay Description:Binding affinity to amyloid beta (1 to 42) (unknown origin) fibrilsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598548(CHEMBL594555)
Affinity DataKd:  120nMAssay Description:Binding affinity to amyloid beta (1 to 42) (unknown origin) fibrilsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50484499(CHEMBL1926770)
Affinity DataKd:  167nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50484500(CHEMBL1926775)
Affinity DataKd:  192nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50484501(CHEMBL1926771)
Affinity DataKd:  222nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM195591(US9216974,Resorufin | US9333197, Resorufin)
Affinity DataKd:  225nMAssay Description:To determine the Ki values, fixed brain tissues prepared from 15-month-old Tg2576 mice (N=5) will be incubated for 30 min with 1 μM methoxy-X34 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50103964(CHEMBL3593932)
Affinity DataKd:  271nMAssay Description:Binding affinity amyloid beta (1 to 42) (unknown origin) expressed in Escherichia coli after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50484504(CHEMBL1926773)
Affinity DataKd:  278nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50484503(CHEMBL1926774)
Affinity DataKd:  286nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM512913(US11091444, Compound FAH-3 | US11142505, FAH #3)
Affinity DataKd:  300nMAssay Description:β-sectretase inhibitor IV from Calbiochem (cat #565788).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50100134(2-(4-Dimethylamino-phenyl)-3,6-dimethyl-benzothiaz...)
Affinity DataKd:  384nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598563(CHEMBL5175890)
Affinity DataKd:  445nMAssay Description:Binding affinity to amyloid beta (1 to 42) (unknown origin) aggregatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM195598(US9216974, WC-5-4)
Affinity DataKd:  537nMAssay Description:To determine the Ki values, fixed brain tissues prepared from 15-month-old Tg2576 mice (N=5) will be incubated for 30 min with 1 μM methoxy-X34 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598544(CHEMBL5204342)
Affinity DataKd:  660nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) oligomerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM195599(US9216974, WC-5-2)
Affinity DataKd:  800nMAssay Description:To determine the Ki values, fixed brain tissues prepared from 15-month-old Tg2576 mice (N=5) will be incubated for 30 min with 1 μM methoxy-X34 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM195600(US9216974, WC-5-1)
Affinity DataKd:  828nMAssay Description:To determine the Ki values, fixed brain tissues prepared from 15-month-old Tg2576 mice (N=5) will be incubated for 30 min with 1 μM methoxy-X34 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50598554(CHEMBL5208480)
Affinity DataKd:  830nMAssay Description:Binding affinity to human amyloid beta (1 to 42) aggregates measured by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM195595(US9216974, WC-5-9)
Affinity DataKd:  927nMAssay Description:To determine the Ki values, fixed brain tissues prepared from 15-month-old Tg2576 mice (N=5) will be incubated for 30 min with 1 μM methoxy-X34 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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