Compile Data Set for Download or QSAR
maximum 50k data
Found 9 of kd data for polymerid = 49000071,49000072,49000076,49000077,5137
Target5-hydroxytryptamine receptor 3A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50288285(CHEMBL90314 | N-(S)-1-Aza-bicyclo[2.2.2]oct-3-yl-5...)
Affinity DataKd:  0.150nMAssay Description:Compound was tested in vitro for its antagonistic activity against 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50417287(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Affinity DataKd:  0.320nMAssay Description:Binding affinity to human wild type 5-HT3A receptor expressed in HEK293 cells after 24 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50443668(CHEBI:5537 | CHEMBL1290003 | GRANISETRON)
Affinity DataKd:  0.530nMAssay Description:Binding affinity to human wild type 5-HT3A receptor expressed in HEK293 cells after 24 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50000492((zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl...)
Affinity DataKd:  0.600nMAssay Description:Compound was tested for its antagonistic activity against 5-hydroxytryptamine 3 receptor in rat brain using [3H]-zacopride as the radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50288284(4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-iodo-2-...)
Affinity DataKd:  2.60nMAssay Description:Compound was tested for its binding affinity towards 5-HT-3 receptor in whole rat brain using (S)-[125I]-zacopride as the radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50060685(9-Fluoro-4-(4-methyl-piperazin-1-yl)-pyrrolo[1,2-a...)
Affinity DataKd:  64.6nMAssay Description:Antagonist activity at 5HT3 receptor in spontaneously beating guinea pig right atrium assessed as inhibition of serotonin-induced maximum response by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50426730(CHEMBL2322133)
Affinity DataKd:  83nMAssay Description:Binding affinity to C-terminal-His6-tagged 5HT3A receptor (unknown origin) expressed in HEK293 cells after 2 hrs by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50081969(9-Methyl-4-(4-methyl-piperazin-1-yl)-pyrrolo[1,2-a...)
Affinity DataKd:  955nMAssay Description:Antagonist activity at 5HT3 receptor in spontaneously beating guinea pig right atrium assessed as inhibition of serotonin-induced maximum response by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50248045((S)-1-(2-fluorophenyl)ethyl (S)-quinuclidin-3-ylca...)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed