Compile Data Set for Download or QSAR
maximum 50k data
Found 5 of kd data for polymerid = 5747
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50318382(3-[pyridine-2-yl)ethynyl]cyclohex-2-enone-O-fluoro...)
Affinity DataKd:  0.600nMAssay Description:Binding affinity to mGluR5 ligand binding site 1 in Sprague-Dawley rat brain P2 membrane after 45 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50198702((E)-3-((6-methylpyridin-2-yl)ethynyl)cyclohex-2-en...)
Affinity DataKd:  2.30nMAssay Description:Binding affinity at mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50395923(CHEMBL2164550)
Affinity DataKd:  9.40nMAssay Description:Binding affinity to mGluR5 in Sprague-Dawley rat striatum after 60 mins by autoradiographic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50318382(3-[pyridine-2-yl)ethynyl]cyclohex-2-enone-O-fluoro...)
Affinity DataKd:  13.7nMAssay Description:Binding affinity to mGluR5 ligand binding site 2 in Sprague-Dawley rat brain P2 membrane after 45 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50395544(CHEMBL2164788)
Affinity DataKd:  70nMAssay Description:Binding affinity to mGluR5 receptor in Sprague-Dawley rat brain by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed