Compile Data Set for Download or QSAR
maximum 50k data
Found 12 of kd data for polymerid = 6145
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California-Riverside

Curated by ChEMBL
LigandPNGBDBM50287585(CHEMBL4169775)
Affinity DataKd: <50nMAssay Description:Binding affinity to recombinant human MMP12 catalytic domain (Gly106 to Gly26 residues) expressed in Escherichia coli BL21 codon plus by 1D 1H alipha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California-Riverside

Curated by ChEMBL
LigandPNGBDBM50287585(CHEMBL4169775)
Affinity DataKd: <50nMAssay Description:Binding affinity to recombinant human MMP12 catalytic domain (Gly106 to Gly26 residues) expressed in Escherichia coli BL21 codon plus by 2D [15N,1H] ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California-Riverside

Curated by ChEMBL
LigandPNGBDBM29018((1S,5S,7R)-3-N-hydroxy-7-N-[(4-phenylphenyl)methyl...)
Affinity DataIC50:  1.49E+5nM Kd:  1.54E+5nMpH: 7.0 T: 2°CAssay Description:The NMR experiments were performed to determine the binding affinity (KD) for the MMP-12 catalytic domain. The alteration of the chemical shifts indu...More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California-Riverside

Curated by ChEMBL
LigandPNGBDBM29017((1S,5S,7R)-N-hydroxy-3-[(4-phenylphenyl)methyl]-6,...)
Affinity DataIC50:  3.99E+5nM Kd: >5.00E+5nMpH: 7.0 T: 2°CAssay Description:The NMR experiments were performed to determine the binding affinity (KD) for the MMP-12 catalytic domain. The alteration of the chemical shifts indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California-Riverside

Curated by ChEMBL
LigandPNGBDBM29016((1R,5S,7R)-N-hydroxy-2-oxo-3-[(4-phenylphenyl)meth...)
Affinity DataIC50:  4.25E+5nM Kd: >5.00E+5nMpH: 7.0 T: 2°CAssay Description:The NMR experiments were performed to determine the binding affinity (KD) for the MMP-12 catalytic domain. The alteration of the chemical shifts indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California-Riverside

Curated by ChEMBL
LigandPNGBDBM50246196(CHEMBL4065195)
Affinity DataKd:  8.75E+5nMAssay Description:Binding affinity to human 15N-labeled MMP-12 catalytic domain (G106 to G263 residues) expressed in Escherichia coli BL21 Gold by 1H NSQC NMR methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California-Riverside

Curated by ChEMBL
LigandPNGBDBM29014((1R,5S,7R)-2-oxo-3-[(4-phenylphenyl)methyl]-6,8-di...)
Affinity DataIC50:  9.54E+5nM Kd: >1.00E+6nMpH: 7.0 T: 2°CAssay Description:The NMR experiments were performed to determine the binding affinity (KD) for the MMP-12 catalytic domain. The alteration of the chemical shifts indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California-Riverside

Curated by ChEMBL
LigandPNGBDBM29015((1S,5S,7R)-3-[(4-phenylphenyl)methyl]-6,8-dioxa-3-...)
Affinity DataIC50:  8.35E+5nM Kd: >1.00E+6nMpH: 7.0 T: 2°CAssay Description:The NMR experiments were performed to determine the binding affinity (KD) for the MMP-12 catalytic domain. The alteration of the chemical shifts indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California-Riverside

Curated by ChEMBL
LigandPNGBDBM29022(ethyl 1-(hydroxycarbamoyl)piperidine-4-carboxylate...)
Affinity DataKd:  3.40E+6nMpH: 7.2 T: 2°CAssay Description:The NMR experiments were performed to determine the binding affinity (KD) for the MMP-12 catalytic domain. The alteration of the chemical shifts indu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California-Riverside

Curated by ChEMBL
LigandPNGBDBM29021((1R,5S,7R)-3-benzyl-N-hydroxy-2-oxo-6,8-dioxa-3-az...)
Affinity DataKd: >1.00E+7nMpH: 7.2 T: 2°CAssay Description:The NMR experiments were performed to determine the binding affinity (KD) for the MMP-12 catalytic domain. The alteration of the chemical shifts indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California-Riverside

Curated by ChEMBL
LigandPNGBDBM29020((1S,5S,7R)-3-benzyl-6,8-dioxa-3-azabicyclo[3.2.1]o...)
Affinity DataKd: >1.00E+7nMpH: 7.2 T: 2°CAssay Description:The NMR experiments were performed to determine the binding affinity (KD) for the MMP-12 catalytic domain. The alteration of the chemical shifts indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California-Riverside

Curated by ChEMBL
LigandPNGBDBM29019((1R,5S,7R)-3-benzyl-2-oxo-6,8-dioxa-3-azabicyclo[3...)
Affinity DataKd: >1.00E+7nMpH: 7.2 T: 2°CAssay Description:The NMR experiments were performed to determine the binding affinity (KD) for the MMP-12 catalytic domain. The alteration of the chemical shifts indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed