Compile Data Set for Download or QSAR
maximum 50k data
Found 6 of kd data for polymerid = 750
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM21492(4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]quinoline | CH...)
Affinity DataKd:  5nMAssay Description:Dissociation constant for TGF-beta receptor type IMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50533235(CHEMBL4576833)
Affinity DataKd:  10nMAssay Description:Inhibition of ALK5 (unknown origin) using fluorescein-labeled peptide substrate incubated for 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50533235(CHEMBL4576833)
Affinity DataKd:  10nMAssay Description:Inhibition of ALK5 (unknown origin) using fluorescein-labeled peptide substrate incubated for 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50311017(CHEMBL1078178 | Momelotinib | N-(cyanomethyl)-4-(2...)
Affinity DataIC50:  205nM Kd:  670nMAssay Description:Biochemical binding assays (DiscoveRx) and in vitro enzyme inhibition assays (LanthaScreen, Life Technologies) were conducted to determine the bindin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50463507(CHEMBL4247751)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to human ALK5 by KdELECT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50463510(CHEMBL4244382)
Affinity DataKd:  1.90E+4nMAssay Description:Binding affinity to human ALK5 by KdELECT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed