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Found 8 of kd data for polymerid = 9627
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
Propellon Therapeutics

US Patent
LigandPNGBDBM552953(N-[4-fluoro-5-(2- morpholin-4-ylpyrimidin- 5-yl)-2...)
Affinity DataKd: <0.5nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
Propellon Therapeutics

US Patent
LigandPNGBDBM553008(N-(5-(2- morpholinopyrimidin-5- yl)-2-((3R,5S)-3,4...)
Affinity DataKd:  3.5nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
Propellon Therapeutics

US Patent
LigandPNGBDBM553032(N-[4-chloro-5-(2- morpholin-4-ylpyrimidin- 5-yl)-2...)
Affinity DataKd:  10nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
Propellon Therapeutics

US Patent
LigandPNGBDBM553011(N-[4-methyl-5-(2- morpholin-4-ylpyrimidin- 5-yl)-2...)
Affinity DataKd:  26nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
Propellon Therapeutics

US Patent
LigandPNGBDBM553005(N-[4-methoxy-5-(2- morpholin-4- ylpyrimidin-5-yl)-...)
Affinity DataKd: >200nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
Propellon Therapeutics

US Patent
LigandPNGBDBM50092310(CHEMBL3581661 | US9675697, Cpd. No. 23)
Affinity DataKd:  9.50E+3nMAssay Description:Binding affinity to biotinylated MLL1 (1566 to 1784 amino acid residues) (unknown origin) expressed in Rosetta2 cells by bio-layer interferometry met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
Propellon Therapeutics

US Patent
LigandPNGBDBM553009(N-[5-(2-morpholin-4- ylpyrimidin-5-yl)-2-[rac- (3R...)
Affinity DataKd: >1.00E+4nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
Propellon Therapeutics

US Patent
LigandPNGBDBM50282115(CHEMBL4165111)
Affinity DataKd:  2.00E+4nMAssay Description:Binding affinity to 15N-labeled GST-tagged MLL1 PHD3 finger domain (1565 to 1627 residues) (unknown origin) expressed in Escherichia coli Rosetta2 BL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed