TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Competitive inhibition of LMW-PTP (unknown origin) assessed as inhibition constant by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 270nMAssay Description:Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1 by competitive inhibition assayMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1 by competitive inhibition assayMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Competitive inhibition of His-tagged LMW-PTP isoform A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as ...More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 1.70E+3nMAssay Description:Competitive inhibition of LMW-PTP isoform B (unknown origin) using para-nitrophenyl phosphate as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 2.23E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1 by mixed type inhibition assayMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1 by mixed type inhibition assayMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 2.68E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1 by mixed type inhibition assayMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 3.20E+3nMAssay Description:Competitive inhibition of His-tagged LMW-PTP isoform A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as ...More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 6.20E+3nMAssay Description:Inhibition of LMW-PTP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectro...More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 7.80E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1 by mixed type inhibition assayMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 1.30E+4nMAssay Description:Competitive inhibition of LMW-PTP isoform A (unknown origin)More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 1.48E+4nMAssay Description:Inhibition of human HCPTPAMore data for this Ligand-Target Pair
TargetTartrate-resistant acid phosphatase type 5(Sus scrofa)
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 3.30E+4nMAssay Description:Competitive inhibition of pig purple acid phosphatase Fe(3)Fe(2) state assessed as enzyme-inhibitor complex using pNPP as substrate by UV/Vis spectro...More data for this Ligand-Target Pair
TargetTartrate-resistant acid phosphatase type 5(Sus scrofa)
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 4.20E+4nMAssay Description:Competitive inhibition of pig purple acid phosphatase Fe(3)Fe(2) state assessed as enzyme-inhibitor complex using pNPP as substrate by UV/Vis spectro...More data for this Ligand-Target Pair
TargetTartrate-resistant acid phosphatase type 5(Sus scrofa)
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 4.90E+4nMAssay Description:Competitive inhibition of pig purple acid phosphatase Fe(3)Fe(2) state assessed as enzyme-inhibitor complex using pNPP as substrate by UV/Vis spectro...More data for this Ligand-Target Pair
TargetTartrate-resistant acid phosphatase type 5(Sus scrofa)
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 1.20E+5nMAssay Description:Competitive inhibition of pig purple acid phosphatase Fe(3)Fe(2) state assessed as enzyme-inhibitor complex using pNPP as substrate by UV/Vis spectro...More data for this Ligand-Target Pair
Affinity DataKi: 1.85E+5nMAssay Description:Competitive inhibition of red kidney bean purple acid phosphatase Fe(3)Fe(2) state assessed as enzyme-inhibitor complex using pNPP as substrate by UV...More data for this Ligand-Target Pair
TargetTartrate-resistant acid phosphatase type 5(Sus scrofa)
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 1.90E+5nMAssay Description:Competitive inhibition of pig purple acid phosphatase Fe(3)Fe(2) state assessed as enzyme-inhibitor complex using pNPP as substrate by UV/Vis spectro...More data for this Ligand-Target Pair
Affinity DataKi: 3.40E+5nMAssay Description:Competitive inhibition of red kidney bean purple acid phosphatase Fe(3)Fe(2) state assessed as enzyme-inhibitor complex using pNPP as substrate by UV...More data for this Ligand-Target Pair
Affinity DataKi: 4.00E+5nMAssay Description:Competitive inhibition of red kidney bean purple acid phosphatase Fe(3)Fe(2) state assessed as enzyme-inhibitor complex using pNPP as substrate by UV...More data for this Ligand-Target Pair
Affinity DataKi: 5.30E+5nMAssay Description:Competitive inhibition of red kidney bean purple acid phosphatase Fe(3)Fe(2) state assessed as enzyme-inhibitor complex using pNPP as substrate by UV...More data for this Ligand-Target Pair
TargetTartrate-resistant acid phosphatase type 5(Sus scrofa)
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 6.30E+5nMAssay Description:Competitive inhibition of pig purple acid phosphatase Fe(3)Fe(2) state assessed as enzyme-inhibitor complex using pNPP as substrate by UV/Vis spectro...More data for this Ligand-Target Pair
Affinity DataKi: 9.20E+5nMAssay Description:Competitive inhibition of red kidney bean purple acid phosphatase Fe(3)Fe(2) state assessed as enzyme-inhibitor complex using pNPP as substrate by UV...More data for this Ligand-Target Pair