Affinity DataEC50: 13.8nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 360nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation preincubated with M372049 for 15 mins followed by compound treat...More data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 390nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 470nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation preincubated with M372049 for 15 mins followed by compound treat...More data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 860nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 970nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.16E+3nMAssay Description:Agonist activity at NPRC in wild type mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 1.43E+3nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.58E+3nMAssay Description:Agonist activity at NPRC in wild type mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+3nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+3nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.51E+3nMAssay Description:Agonist activity at NPRC in wild type mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.64E+3nMAssay Description:Agonist activity at NPRC in knock out mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.80E+3nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Affinity DataEC50: 3.02E+3nMAssay Description:Agonist activity at NPRC in knock out mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 3.45E+3nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 3.76E+3nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 4.43E+3nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 6.20E+3nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 6.24E+3nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 8.64E+3nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation preincubated with M372049 for 15 mins followed by compound treat...More data for this Ligand-Target Pair
Affinity DataEC50: 1.01E+4nMAssay Description:Agonist activity at NPRC in knock out mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 1.55E+4nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.74E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.03E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 2.22E+4nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 3.20E+4nMAssay Description:Displacement of Flu-P19 probe from human NPR-C (27 to 541 residues) by fluorescence polarization analysisMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 6.00E+4nMAssay Description:Displacement of Flu-P19 probe from human NPR-C (27 to 541 residues) by fluorescence polarization analysisMore data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 7.81E+4nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 1.02E+5nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataEC50: 3.27E+5nMAssay Description:Displacement of Flu-P19 probe from human NPR-C (27 to 541 residues) by fluorescence polarization analysisMore data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataKi: 0.0590nMAssay Description:Displacement of [125I]- ANP from the Atrial Natriuretic Peptide Clearance Receptor.More data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Displacement of [125I]- ANP from the Atrial Natriuretic Peptide Clearance Receptor.More data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataKi: 0.25nMAssay Description:Apparent binding affinity for non-vasorelaxant receptorMore data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [125I]- ANP from the Atrial Natriuretic Peptide Clearance Receptor.More data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Displacement of [125I]- ANP from the Atrial Natriuretic Peptide Clearance Receptor.More data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataKi: 0.480nMAssay Description:Displacement of [125I]- ANP from the Atrial Natriuretic Peptide Clearance Receptor.More data for this Ligand-Target Pair
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataKi: 0.490nMAssay Description:Displacement of [125I]- ANP from the Atrial Natriuretic Peptide Clearance Receptor.More data for this Ligand-Target Pair