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Found 117 Enz. Inhib. hit(s) with Target = 'Atrial natriuretic peptide receptor 3'
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM287915(CNP-22 | CNP-53 | Natriuretic peptide, C-type | US...)
Affinity DataEC50:  13.8nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50604566(CHEMBL5193490)
Affinity DataEC50:  360nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation preincubated with M372049 for 15 mins followed by compound treat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50604566(CHEMBL5193490)
Affinity DataEC50:  390nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50604564(CHEMBL5191531)
Affinity DataEC50:  470nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation preincubated with M372049 for 15 mins followed by compound treat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50604565(CHEMBL5180826)
Affinity DataEC50:  860nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50604564(CHEMBL5191531)
Affinity DataEC50:  970nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM50604564(CHEMBL5191531)
Affinity DataEC50:  1.16E+3nMAssay Description:Agonist activity at NPRC in wild type mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50604564(CHEMBL5191531)
Affinity DataEC50:  1.43E+3nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM50604565(CHEMBL5180826)
Affinity DataEC50:  1.58E+3nMAssay Description:Agonist activity at NPRC in wild type mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM287928(US10087144, Compound 187)
Affinity DataEC50:  1.60E+3nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM287916(US10087144, Compound 28)
Affinity DataEC50:  1.60E+3nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM50604566(CHEMBL5193490)
Affinity DataEC50:  2.51E+3nMAssay Description:Agonist activity at NPRC in wild type mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM50604564(CHEMBL5191531)
Affinity DataEC50:  2.64E+3nMAssay Description:Agonist activity at NPRC in knock out mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM287918(US10087144, Compound 118)
Affinity DataEC50:  2.80E+3nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM50604566(CHEMBL5193490)
Affinity DataEC50:  3.02E+3nMAssay Description:Agonist activity at NPRC in knock out mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50604570(CHEMBL5197280)
Affinity DataEC50:  3.45E+3nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50604572(CHEMBL5208520)
Affinity DataEC50:  3.76E+3nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50604571(CHEMBL5174523)
Affinity DataEC50:  4.43E+3nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50604569(CHEMBL5170051)
Affinity DataEC50:  6.20E+3nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50604567(CHEMBL5171798)
Affinity DataEC50:  6.24E+3nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50604565(CHEMBL5180826)
Affinity DataEC50:  8.64E+3nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation preincubated with M372049 for 15 mins followed by compound treat...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM50604565(CHEMBL5180826)
Affinity DataEC50:  1.01E+4nMAssay Description:Agonist activity at NPRC in knock out mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50604565(CHEMBL5180826)
Affinity DataEC50:  1.55E+4nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM287927(US10087144, Compound 178)
Affinity DataEC50:  1.74E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM287932(US10087144, Compound 202)
Affinity DataEC50:  2.03E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50604569(CHEMBL5170051)
Affinity DataEC50:  2.22E+4nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50604566(CHEMBL5193490)
Affinity DataEC50:  3.20E+4nMAssay Description:Displacement of Flu-P19 probe from human NPR-C (27 to 541 residues) by fluorescence polarization analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM287919(US10087144, Compound 119)
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM287929(US10087144, Compound 188)
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM287930(US10087144, Compound 200)
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM287931(US10087144, Compound 201)
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM287917(US10087144, Compound 117)
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM287920(US10087144, Compound 171)
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM287926(US10087144, Compound 177)
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM287925(US10087144, Compound 176)
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM287924(US10087144, Compound 175)
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM287923(US10087144, Compound 174)
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM287921(US10087144, Compound 172)
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtrial natriuretic peptide receptor 3(Mus musculus)
Ucl Business

US Patent
LigandPNGBDBM287922(US10087144, Compound 173)
Affinity DataEC50: >5.00E+4nMAssay Description:Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50604568(CHEMBL5175209)
Affinity DataEC50:  6.00E+4nMAssay Description:Displacement of Flu-P19 probe from human NPR-C (27 to 541 residues) by fluorescence polarization analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50604570(CHEMBL5197280)
Affinity DataEC50:  7.81E+4nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50604566(CHEMBL5193490)
Affinity DataEC50:  1.02E+5nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50604567(CHEMBL5171798)
Affinity DataEC50:  3.27E+5nMAssay Description:Displacement of Flu-P19 probe from human NPR-C (27 to 541 residues) by fluorescence polarization analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50091753(CHEMBL405854 | H-Ser-Leu-Arg-Arg-Ser-Ser-cyclic(Cy...)
Affinity DataKi:  0.0590nMAssay Description:Displacement of [125I]- ANP from the Atrial Natriuretic Peptide Clearance Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50091751(CHEMBL411542 | Cyclic-(Cys-Phe-Gly-Gly-Arg-Ile-Asp...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]- ANP from the Atrial Natriuretic Peptide Clearance Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50016816(CHEMBL412913 | S-S-C-F-G-G-R-I-D-R-I-G-A-Q-S-G-L-G...)
Affinity DataKi:  0.25nMAssay Description:Apparent binding affinity for non-vasorelaxant receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50091758((S)-N-[(S)-4-Guanidino-1-((S)-2-methyl-butylcarbam...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]- ANP from the Atrial Natriuretic Peptide Clearance Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50091752((S)-3-{(2S,3S)-2-[(S)-5-Guanidino-2-(2-{4-[(naphth...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [125I]- ANP from the Atrial Natriuretic Peptide Clearance Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50091761((S)-N-[(S)-4-Guanidino-1-((S)-2-methyl-butylcarbam...)
Affinity DataKi:  0.480nMAssay Description:Displacement of [125I]- ANP from the Atrial Natriuretic Peptide Clearance Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50091757(CHEMBL264744 | Cyclic-(Cys-Phe-Gly-Gly-Ala-Ile-Asp...)
Affinity DataKi:  0.490nMAssay Description:Displacement of [125I]- ANP from the Atrial Natriuretic Peptide Clearance Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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