Affinity DataIC50: 5.30nM EC50: 10nMpH: 6.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nM EC50: 40nMAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Affinity DataEC50: 138nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as induction of accumulation of lip10More data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nM EC50: 318nMAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.35E+3nM EC50: 480nMAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Affinity DataEC50: 580nMAssay Description:Inhibition of Cathepsin S in human Raji cells assessed as increase in Lip10 accumulation after 24 hrs by SDS-PAGE analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.41E+4nM EC50: 740nMAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+4nM EC50: 790nMpH: 6.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+3nMAssay Description:Inhibition of Cathepsin S in human Raji cells assessed as increase in Lip10 accumulation after 24 hrs by SDS-PAGE analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nM EC50: 1.34E+3nMpH: 6.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+4nM EC50: 2.90E+3nMpH: 6.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+4nM EC50: 4.80E+3nMpH: 6.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nM EC50: 6.70E+3nMAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nM EC50: 8.50E+3nMAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+4nM EC50: >1.00E+4nMAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+4nM EC50: >1.00E+4nMpH: 6.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Inhibition of recombinant human cathepsin S using Z-VVR-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1...More data for this Ligand-Target Pair
Affinity DataKi: <0.100nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Inhibition of human cathepsin S using Z-Phe-Arg-AMC fluorogenic substrate fluorogenic substrate incubated for 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Inhibition of human cathepsin S after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of human cathepsin S after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of human cathepsin S after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Inhibition of human cathepsin S after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.176nMAssay Description:Inhibition of human cathepsin S using Z-Phe-Arg-AMC fluorogenic substrate fluorogenic substrate incubated for 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Inhibition of human cathepsin S after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of human cathepsin S after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of human cathepsin S after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Affinity DataKi: <0.25nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...More data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Inhibition of human cathepsin S after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Inhibition of human cathepsin S after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...More data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:Inhibition of human cathepsin S after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.550nMAssay Description:Inhibition of human cathepsin S using Z-Phe-Val-Arg-pNA as substrate after 80 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.560nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.777nMAssay Description:Inhibition of human cathepsin S using Z-Phe-Arg-AMC fluorogenic substrate fluorogenic substrate incubated for 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.830nMAssay Description:Inhibition of human cathepsin S after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.860nMAssay Description:Inhibition of human cathepsin S after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -53.4kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus by fluorescence assayMore data for this Ligand-Target Pair