Compile Data Set for Download or QSAR
maximum 50k data
Found 374 Enz. Inhib. hit(s) with Target = 'Huntingtin'
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM50257750(CHEMBL494325 | N-allyl-6-bromoquinazolin-4-amine |...)
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of Huntingtin protein (unknown origin) aggregation by yeast based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM50257749(6-bromo-N-propylquinazolin-4-amine | CHEMBL449571)
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of Huntingtin protein (unknown origin) aggregation by yeast based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM50257751(CHEMBL494326 | N-benzyl-6-bromoquinazolin-4-amine ...)
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of Huntingtin protein (unknown origin) aggregation by yeast based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37518(MLS000074703 | N-[2-(tert-butylamino)-2-keto-ethyl...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37519(5-Piperidin-1-ylmethyl-furan-2-carboxylic acid (4-...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37520(2-[[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfa...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37521(2-[5-(4-Fluoro-phenyl)-1-methyl-1H-imidazol-2-ylsu...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37522(3-(3,6-diketo-1H-pyridazin-2-yl)propionic acid | 3...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37523(3-(3,5-Dimethyl-[1,2,4]triazol-1-yl)-butyric acid ...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37524(1-(2,5-Dimethoxy-phenyl)-2-[5-(3,4-dimethoxy-pheny...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37525(2,2,2-trifluoro-N-(2-keto-1,3-dimethyl-benzimidazo...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37526(2-butyl-1-[2-(2-butyl-1-imidazolyl)ethyl]imidazole...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37527(2-[[5-[(4-chloroanilino)methyl]-1,3,4-oxadiazol-2-...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37528(4-Ethynyl-1,2,6-trimethyl-piperidin-4-ol | 4-ethyn...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37529(Furan-2-carboxylic acid (6,7,8,9-tetrahydro-5H-10-...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37530(4-Chloro-N-(5-methyl-isoxazol-3-yl)-benzamide | 4-...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37531((4-Methyl-quinazolin-2-yl)-[5-(tetrahydro-furan-2-...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37532(1-Amino-3-o-tolyloxy-propan-2-ol | 1-amino-3-(2-me...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37533((2E,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylene...)
Affinity DataIC50: <10nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37534((2E,4R,12aR)-2-[amino(hydroxy)methylene]-4,7-bis(d...)
Affinity DataIC50: <100nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37535(CHLORTETRACYCLINE HYDROCHLORIDE | MLS000069428 | S...)
Affinity DataIC50: <10nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37536((2E,4S,4aR,5S,5aR,6S,12aS)-2-[amino(hydroxy)methyl...)
Affinity DataIC50: <100nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM32023((2E,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylene...)
Affinity DataIC50:  80nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37537(2-(2-imidazolin-2-ylamino)ethanol;hydroiodide | 2-...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37538((8S,8aR)-6-amino-5,7,7-tricyano-8-(3-pyridinyl)-1,...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37539(7-(2-fluorobenzyl)-1,3-dimethyl-8-(piperonylamino)...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37540(5-amino-3-(4-methoxyphenyl)-2-methyl-4-imidazoleca...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37541(MLS000030505 | SMR000040116 | cid_659091)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37542(1-(4-cyclopentyl-1-piperazinyl)-3-methyl-4-pyrido[...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37543(4-bromanyl-2-methyl-N-(2-methylsulfanylphenyl)pyra...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37544(1-[3-(1-cyano-2-isopropoxy-2-keto-ethyl)quinoxalin...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM33514(2-(2-bromophenyl)-5-[(5-methyl-2-furanyl)methylide...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM36921(6-cyclohexyl-3-(3-methoxyphenyl)-[1,2,4]triazolo[3...)
Affinity DataIC50: >4.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37545((2,3-dimethoxybenzylidene)-(2-methylbenzimidazol-1...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37546(2-(3,4-dimethoxyphenyl)-5-(4-morpholinyl)-4-oxazol...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37547(3-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(4-m...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37548((5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37549(5,6-dihydro-4H-1,3-thiazin-2-yl(o-tolyl)amine | ML...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37550(3-[4-(2,5-dimethoxyphenyl)-5-(2-methylallylthio)-1...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37551(MLS000082016 | N-[2-(4-methoxyphenyl)ethyl]-2,3-di...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37552(6-(1-benzofuran-2-yl)-3-[(3,4-dimethoxyphenyl)meth...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37553(5-(2-hydroxy-5-methyl-benzoyl)-2-keto-1-(tetrahydr...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37554(2-(4-fluoroanilino)-N-(2-furanylmethyl)benzamide |...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37555(5-[(1-benzyl-3,5-dimethyl-pyrazole-4-carbonyl)amin...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37556(1-[4-(2-furoyl)piperazino]-2-[[5-(2-furyl)-4-pheny...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37557(1-(4-ethylthieno[3,2-b]pyrrol-5-yl)carbonyl-N-(3-p...)
Affinity DataIC50: >4.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37558(MLS000047411 | N-(2-fluorophenyl)-3-[4-(4-fluoroph...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37559(4-N-cyclooctyl-1-N,1-N-dimethylpiperidine-1,4-dica...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37560(MLS000045970 | N-[2-(3,4-dimethoxyphenyl)ethyl]-4-...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM37561(2-amino-4-phenyl-phenol | 2-amino-4-phenylphenol |...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
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