Found 3747 Enz. Inhib. hit(s) with Target = 'Melatonin receptor' 
Affinity DataEC50: <0.0100nMAssay Description:Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skinMore data for this Ligand-Target Pair
Affinity DataEC50: <0.0100nMAssay Description:Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skinMore data for this Ligand-Target Pair
Affinity DataEC50: <0.0100nMAssay Description:Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skinMore data for this Ligand-Target Pair
Affinity DataEC50: <0.0100nMAssay Description:Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skinMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0150nMAssay Description:Agonist activity at human MT1 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 30 mins by AlphaS...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0210nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as decrease in forskolin-stimulated cAMP release after 30 mins by multilabel p...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0220nMAssay Description:Agonist activity at human MT1 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 30 mins by AlphaS...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.0240nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells coexpressing Galpha protein 16z25 assessed as increase in calcium mobilization measured...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0260nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as decrease in forskolin-stimulated cAMP release after 30 mins by multilabel p...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0350nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as increase in forskolin induced cAMP production incubated at 37 degreeC by Hi...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0360nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as increase in forskolin induced cAMP production incubated at 37 degreeC by Hi...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0370nMAssay Description:Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skinMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0370nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as increase in forskolin induced cAMP production incubated at 37 degreeC by Hi...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0400nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as increase in forskolin induced cAMP production incubated at 37 degreeC by Hi...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0420nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as increase in forskolin induced cAMP production incubated at 37 degreeC by Hi...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0420nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as increase in forskolin induced cAMP production incubated at 37 degreeC by Hi...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.0500nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells coexpressing Galpha protein 16z25 assessed as increase in calcium mobilization measured...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0500nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.0500nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.0600nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0630nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as increase in forskolin induced cAMP production incubated at 37 degreeC by Hi...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.0690nMAssay Description:Agonist activity at human melatonin receptor-2 transfected in CHO cell membranes after 1 hr by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0692nMAssay Description:Agonist activity at human melatonin MT1 receptor stably expressing in human HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumula...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.0700nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0794nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.0900nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.0900nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.0960nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0980nMAssay Description:Agonist activity at human melatonin receptor-1 transfected in CHO cell membranes after 1 hr by GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.100nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.100nMAssay Description:Agonist activity at human human MT2 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.100nMAssay Description:Agonist potency determined by [35S]-GTP gamma-S binding assay using CHO cell lines for Melatonin receptor type 1BMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.100nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.110nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as increase in cAMP levels incubated at 28 degreeC by cellular dielectric spec...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.110nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells coexpressing Galpha protein 16z25 assessed as increase in calcium mobilization measured...More data for this Ligand-Target Pair
Affinity DataEC50: 0.140nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as increase in cAMP levels incubated at 28 degreeC by cellular dielectric spec...More data for this Ligand-Target Pair
Affinity DataEC50: 0.140nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as increase in cAMP levels incubated at 28 degreeC by cellular dielectric spec...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.170nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.170nMAssay Description:Intrinsic activity evaluated on [35S]-GTP -gamma-S binding in Chinese hamster ovarian (CHO) cells, stably expressing human Melatonin receptor type 1AMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.174nMAssay Description:Agonist activity at human melatonin MT2 receptor stably expressing in human HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumula...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.180nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.180nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.180nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.180nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as increase in cAMP levels incubated at 28 degreeC by cellular dielectric spec...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.190nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.200nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.200nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University Of Science And Technology
Curated by ChEMBL
Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataEC50: 0.200nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
