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Found 8 Enz. Inhib. hit(s) with Target = 'NS5'
TargetNS5B(Hepatitis C virus)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50183494(2-[3-({[(2,6-dichlorobenzyl)oxy]carbonyl}amino)-2-...)
Affinity DataIC50:  258nMAssay Description:Displacement of 0.1 uM UTP from NS5B in Hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNS5B(Hepatitis C virus)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50183494(2-[3-({[(2,6-dichlorobenzyl)oxy]carbonyl}amino)-2-...)
Affinity DataIC50: >500nMAssay Description:Displacement of 1 uM UTP from NS5B in Hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNS5B(Hepatitis C virus)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50183494(2-[3-({[(2,6-dichlorobenzyl)oxy]carbonyl}amino)-2-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of 5 uM UTP from NS5B in Hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNS5B(Hepatitis C virus)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50332459(((2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)...)
Affinity DataIC50:  5.94E+3nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNS5B(Hepatitis C virus)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50183494(2-[3-({[(2,6-dichlorobenzyl)oxy]carbonyl}amino)-2-...)
Affinity DataIC50:  302nMAssay Description:Displacement of 100 uM PPi from NS5B in Hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNS5B(Hepatitis C virus)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50183494(2-[3-({[(2,6-dichlorobenzyl)oxy]carbonyl}amino)-2-...)
Affinity DataIC50:  882nMAssay Description:Displacement of 500 uM PPi from NS5B in Hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNS5B(Hepatitis C virus)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50183494(2-[3-({[(2,6-dichlorobenzyl)oxy]carbonyl}amino)-2-...)
Affinity DataIC50:  730nMAssay Description:Inhibition of NS5B-mediated RNA synthesis in Hepatitis C virus assessed as decrease in formation of full-length product after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNS5B(Hepatitis C virus)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50183494(2-[3-({[(2,6-dichlorobenzyl)oxy]carbonyl}amino)-2-...)
Affinity DataIC50:  174nMAssay Description:Displacement of 50 uM PPi from NS5B in Hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed