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Found 11 Enz. Inhib. hit(s) with Target = 'Programmed cell death protein 4'
TargetProgrammed cell death protein 4(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM36609(Rapamycin C-7, analog 4 | SIROLIMUS | US11603377, ...)
Affinity DataEC50:  50nMAssay Description:Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death protein 4(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50345546(CHEMBL1784378 | Cryptocaryol G)
Affinity DataEC50:  1.30E+3nMAssay Description:Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death protein 4(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50345543(CHEMBL1784375 | Cryptocaryol D)
Affinity DataEC50:  1.50E+3nMAssay Description:Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death protein 4(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50345542(CHEMBL1784374 | Cryptocaryol C)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death protein 4(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50345544(CHEMBL1784376 | Cryptocaryol E)
Affinity DataEC50:  1.80E+3nMAssay Description:Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death protein 4(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50345547(CHEMBL1784379 | Cryptocaryol H)
Affinity DataEC50:  1.80E+3nMAssay Description:Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death protein 4(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50598483(CHEMBL5170759)
Affinity DataEC50:  2.25E+3nMAssay Description:Inhibition of PDCD4 in human HeLa cells tranfected with pCI-neo-luciferase-PDCD4 3'-UTR plasmid assessed as increase in luciferase activity by lucife...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProgrammed cell death protein 4(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50345541(CHEMBL1784373 | Cryptocaryol B)
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death protein 4(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50345545(CHEMBL1784377 | Cryptocaryol F)
Affinity DataEC50:  3.50E+3nMAssay Description:Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death protein 4(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50345540(CHEMBL1784372 | Cryptocaryol A)
Affinity DataEC50:  4.90E+3nMAssay Description:Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death protein 4(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50000298('2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROX...)
Affinity DataIC50:  880nMAssay Description:Stabilization of Pdcd4 expressed in human HEK293 cells assessed as inhibition of TPA-induced degradation by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed