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Found 7 Enz. Inhib. hit(s) with Target = 'Short transient receptor potential channel 7'
TargetShort transient receptor potential channel 7(Homo sapiens)
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc

Curated by ChEMBL
LigandPNGBDBM50239161(CHEMBL4085233)
Affinity DataEC50:  90nMAssay Description:Agonist activity at human TRPC7 expressed in HEK293 cells assessed as increase in intracellular calcium level measured for 2.5 mins in presence of 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 7(Homo sapiens)
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc

Curated by ChEMBL
LigandPNGBDBM50239160(CHEMBL4060387)
Affinity DataEC50:  213nMAssay Description:Agonist activity at human TRPC7 expressed in HEK293 cells assessed as increase in intracellular calcium level measured for 2.5 mins in presence of 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 7(Homo sapiens)
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc

Curated by ChEMBL
LigandPNGBDBM50239162(CHEMBL4060400)
Affinity DataEC50:  314nMAssay Description:Agonist activity at human TRPC7 expressed in HEK293 cells assessed as increase in intracellular calcium level measured for 2.5 mins in presence of 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 7(Homo sapiens)
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc

Curated by ChEMBL
LigandPNGBDBM50239167(CHEMBL1496110)
Affinity DataEC50:  497nMAssay Description:Agonist activity at human TRPC7 expressed in HEK293 cells assessed as increase in intracellular calcium level measured for 2.5 mins in presence of 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 7(Homo sapiens)
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc

Curated by ChEMBL
LigandPNGBDBM50239167(CHEMBL1496110)
Affinity DataEC50:  1.13E+3nMAssay Description:Agonist activity at human TRPC7 receptor expressed in HEK293 cells assessed as induction of channel current in presence of 0.1 mM Ca2+ by whole cell ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 7(Mus musculus)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM85747(CAS_442-52-4 | CLEMIZOLE HYDROCHLORIDE | NSC_2782 ...)
Affinity DataIC50:  2.65E+4nMAssay Description:Inhibition of YFP-tagged mouse TRPC7 expressed in thapsigargin treated HEK293 cells assessed as reduction in amix-induced calcium level by fluo-4 dye...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 7(Homo sapiens)
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc

Curated by ChEMBL
LigandPNGBDBM50273009(CHEMBL4129809)
Affinity DataIC50:  226nMAssay Description:Inhibition of human TRPC7 expressed in HEK293 cells assessed as reduction in OAG-induced calcium influx after 10 mins by fluo-4/AM dye based FLIPR as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed