Affinity DataEC50: <0.100nMAssay Description:Binding affinity to mouse SMOMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Binding affinity to human SMOMore data for this Ligand-Target Pair
Affinity DataEC50: 0.800nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 0.900nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: <1.5nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Binding affinity to human SMOMore data for this Ligand-Target Pair
Affinity DataEC50: 1.70nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Displacement of BODIPY-labeled cyclopamine from mouse SMO transfected in human HeLa cells by competition binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Binding affinity to human SMOMore data for this Ligand-Target Pair
Affinity DataEC50: 2.30nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 2.60nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 2.90nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 2.90nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Displacement of BODIPY-labeled cyclopamine from human SMO transfected in human HeLa cells by competition binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.10nMAssay Description:Binding affinity to mouse SMOMore data for this Ligand-Target Pair
Affinity DataEC50: 3.10nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 3.10nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 4.70nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 6.70nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 6.80nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 7.5nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Agonist activity at SMO in mouse NIH3T3 cells incubated for 2 hrs by Bright-Glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Agonist activity at SMO in mouse NIH3T3 cells incubated for 2 hrs by Bright-Glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Agonist activity at SMO in mouse NIH3T3 cells incubated for 2 hrs by Bright-Glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Agonist activity at SMO in mouse NIH3T3 cells incubated for 2 hrs by Bright-Glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Displacement of BODIPY-labeled cyclopamine from mouse SMO transfected in human HeLa cells by competition binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Binding affinity to mouse SMOMore data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 24nMAssay Description:Inhibition of Smo in mouse Shh Light2 cells assessed as inhibition of SAG-induced Hh pathway activity by measuring SAG-EC50 at 50 nM measured after 3...More data for this Ligand-Target Pair
Affinity DataEC50: 27nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 27nMAssay Description:Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair