Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 5'
TargetToll-like receptor 5(Homo sapiens)
University Of Colorado Boulder

Curated by ChEMBL
LigandPNGBDBM50239681(CHEMBL4074408)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibitory activity against Herpes simplex virus type-I specific thymidine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 5(Homo sapiens)
University Of Colorado Boulder

Curated by ChEMBL
LigandPNGBDBM50563780(CHEMBL4795714)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human TLR5 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of flag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 5(Homo sapiens)
University Of Colorado Boulder

Curated by ChEMBL
LigandPNGBDBM50552136(CHEMBL4795753)
Affinity DataIC50:  850nMAssay Description:Inhibition of Flagellin-BS binding to human TLR5 expressed in HEK293 cells harboring SEAP reporter gene preincubated for 24 hrs followed by compound ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 5(Homo sapiens)
University Of Colorado Boulder

Curated by ChEMBL
LigandPNGBDBM50543142(CHEMBL4641633)
Affinity DataIC50: >6.50E+3nMAssay Description:Antagonist activity at TLR5 in human PBMC assessed as inhibition of flagellin-induced TNFalpha production preincubated for 30 mins followed by flagel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed