Compile Data Set for Download or QSAR
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Found 46 Enz. Inhib. hit(s) with Target = 'Beta-mannosidase'
TargetBeta-mannosidase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50242067(CHEMBL469435 | alpha-1-C-(1,10,13-Trihydroxytridec...)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of rat epididymis beta-mannosidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50234567(1,4-dideoxy-1,4-imino-D-ribitol | CHEMBL261634 | I...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of rat epididymis beta-mannosidase assessed as p-nitrophenol release by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50279407(2,5-Imino-2,5,7-trideoxy-D-glycero-D-manno-heptito...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of rat epididymis beta-mannosidase assessed as p-nitrophenol release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50279406(2,5-Dideoxy-2,5-imino-glycero-D-manno-heptitol | C...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of rat epididymis beta-mannosidase assessed as p-nitrophenol release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50242267(2,5-imino-1,2,5-trideoxy-D-mannitol | CHEMBL443158)
Affinity DataIC50:  9.30E+4nMAssay Description:Inhibition of rat epididymis beta-mannosidase assessed as p-nitrophenol release by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50242066(CHEMBL511823 | alpha-1-C-(1,2-Dihdroxypropyl)-1,4-...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of rat epididymis beta-mannosidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50279408((2R,3S,4S,5S,6R)-2-((2R,3R,4R,5R)-4-hydroxy-2-(2-h...)
Affinity DataIC50:  1.60E+5nMAssay Description:Inhibition of rat epididymis beta-mannosidase assessed as p-nitrophenol release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50278882((2S,3S,4S,5S,6R)-2-((2R,3S,4S,5R,6R)-3,5-dihydroxy...)
Affinity DataIC50:  1.80E+5nMAssay Description:Inhibition of rat epididymis beta-mannosidase assessed as p-nitrophenol release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50016703(2-Hydroxymethyl-pyrrolidine-3,4-diol | BDBM5003148...)
Affinity DataIC50:  2.90E+5nMAssay Description:Inhibition of rat epididymis beta-mannosidase assessed as p-nitrophenol release by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50234571(2,5-imino-2,5,6-trideoxy-D-manno-heptitol | CHEMBL...)
Affinity DataIC50:  3.20E+5nMAssay Description:Inhibition of rat epididymis beta-mannosidase assessed as p-nitrophenol release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50242065(CHEMBL449851 | alpha-1-C-(2-Hydroxypropyl)-1,4-did...)
Affinity DataIC50:  6.10E+5nMAssay Description:Inhibition of rat epididymis beta-mannosidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Homo sapiens (Human))
S.E.S.N.A.B., Pole Sciences Et Technologie, Universit�

Curated by ChEMBL
LigandPNGBDBM50070029((2Z)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-...)
Affinity DataKi:  25nMAssay Description:The compound was tested for its inhibitory activity against beta-mannosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36374((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Affinity DataKi:  57nM ΔG°:  -43.0kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36375((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Affinity DataKi:  72nM ΔG°:  -42.4kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36376((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Affinity DataKi:  401nM ΔG°:  -38.0kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36384((2R/S,3S,4R,5R)-5-(Hydroxymethyl)piperidine-2,3,4-...)
Affinity DataKi:  975nM ΔG°:  -35.7kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36378(1-[(2-Aminoethyl)amino]-1,5-anhydro-1-deoxy-1-imin...)
Affinity DataKi:  1.00E+3nM ΔG°:  -35.6kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36373((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Affinity DataKi:  1.40E+3nM ΔG°:  -34.8kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36381(1-[(4-Aminobutyl)amino]-1,5-anhydro-1-deoxy-1-imin...)
Affinity DataKi:  1.90E+3nM ΔG°:  -34.0kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36379(1-[(4-Aminobutyl)amino]-1,5-anhydro-1-deoxy-1-imin...)
Affinity DataKi:  2.10E+3nM ΔG°:  -33.7kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36393(1-[(3-Aminopropyl)amino]-1,5-anhydro-1-deoxy-1-imi...)
Affinity DataKi:  2.10E+3nM ΔG°:  -33.7kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36380(1,5-Anhydro-1-deoxy-1-[(3-hydroxypropyl)amino]-1-i...)
Affinity DataKi:  2.20E+3nM ΔG°:  -33.6kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36377((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Affinity DataKi:  2.40E+3nM ΔG°:  -33.4kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50285807(CHEMBL2368787)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition against Beta-mannosidase in snailMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-mannosidase(Homo sapiens (Human))
S.E.S.N.A.B., Pole Sciences Et Technologie, Universit�

Curated by ChEMBL
LigandPNGBDBM50070028(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-...)
Affinity DataKi:  1.00E+4nMAssay Description:The compound was tested for its inhibitory activity against beta-mannosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36385((3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)piperidi...)
Affinity DataKi:  1.10E+4nM ΔG°:  -29.4kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36392((1R,4R,5R,7R,8R)-2-Benzyl-5-(hydroxymethyl)-2-azab...)
Affinity DataKi:  1.30E+4nM ΔG°:  -29.0kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
TargetBeta-mannosidase(Homo sapiens (Human))
S.E.S.N.A.B., Pole Sciences Et Technologie, Universit�

Curated by ChEMBL
LigandPNGBDBM50366566(CHEMBL610071)
Affinity DataKi:  1.70E+4nMAssay Description:The compound was tested for its inhibitory activity against beta-mannosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36382(CID24752823 | N,N-(4-aminobutyl)-D-glucoamidine, 3)
Affinity DataKi:  2.20E+4nM ΔG°:  -27.7kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50285809(CHEMBL2368788)
Affinity DataKi:  1.00E+5nMAssay Description:Inhibition against Beta-mannosidase in snailMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36383((1R,4R,5R,7R,8R)-5-(Hydroxymethyl)-2-azabicyclo[2....)
Affinity DataKi:  5.00E+5nM ΔG°:  -19.6kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Homo sapiens (Human))
S.E.S.N.A.B., Pole Sciences Et Technologie, Universit�

Curated by ChEMBL
LigandPNGBDBM50186734(CHEMBL207910 | D-1,4-dideoxy-4,4-difluoronojirimyc...)
Affinity DataKi: >1.00E+6nMpH: 4.0Assay Description:Inhibition of snail beta mannosidase at pH 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36386((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Affinity DataKi:  1.00E+6nM ΔG°:  -17.8kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Homo sapiens (Human))
S.E.S.N.A.B., Pole Sciences Et Technologie, Universit�

Curated by ChEMBL
LigandPNGBDBM50186733(CHEMBL208152 | L-1,4,6-trideoxy-4,4-difluoronojiri...)
Affinity DataKi: >1.00E+6nMpH: 4.0Assay Description:Inhibition of snail beta mannosidase at pH 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Homo sapiens (Human))
S.E.S.N.A.B., Pole Sciences Et Technologie, Universit�

Curated by ChEMBL
LigandPNGBDBM50186735(CHEMBL208021 | D-1,4-dideoxy-4,4-difluoromannonoji...)
Affinity DataKi: >1.00E+6nMpH: 4.0Assay Description:Inhibition of snail beta mannosidase at pH 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Homo sapiens (Human))
S.E.S.N.A.B., Pole Sciences Et Technologie, Universit�

Curated by ChEMBL
LigandPNGBDBM50186736(CHEMBL380311 | L-1,4-dideoxy-4,4-difluorogulonojir...)
Affinity DataKi: >1.00E+6nMpH: 4.0Assay Description:Inhibition of snail beta mannosidase at pH 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Homo sapiens (Human))
S.E.S.N.A.B., Pole Sciences Et Technologie, Universit�

Curated by ChEMBL
LigandPNGBDBM50186732(CHEMBL206628 | D-1,4,6-trideoxy-4,4-difluoronojiri...)
Affinity DataKi: >1.00E+6nMpH: 4.0Assay Description:Inhibition of snail beta mannosidase at pH 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36390((Z)-D-Gluconhydroximo-1,5-lactam, 15 | CID445248)
Affinity DataKi:  2.00E+6nM ΔG°:  -16.0kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)
Affinity DataKi:  6.00E+6nM ΔG°:  -13.2kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)
Affinity DataKi:  9.00E+6nM ΔG°:  -12.1kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36389(8-Aza-bicyclo[3.2.1]octane-1,2,3,4-tetraol, 14 | C...)
Affinity DataKi:  1.10E+7nM ΔG°:  -11.6kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataKi:  1.40E+7nM ΔG°:  -11.0kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36387((4R,5S,6R)-6-Hydroxymethyl-[1,2]oxazinane-4,5-diol...)
Affinity DataKi:  2.00E+7nM ΔG°:  -10.1kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36388(BDBM36404 | CID54445 | Octahydro-indolizine-1,6,7,...)
Affinity DataKi:  2.30E+7nM ΔG°:  -9.73kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM50065259((2R,3R,4R,5R)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataKi:  3.30E+7nM ΔG°:  -8.80kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-mannosidase(Bacteroides thetaiotaomicron)
The Medical School, Newcastle University

LigandPNGBDBM36391(5-Hydroxymethyl-7-isopropoxy-6-oxa-bicyclo[3.2.2]n...)
Affinity DataKi: >4.00E+8nM ΔG°: >-2.36kJ/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed