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Found 10 Enz. Inhib. hit(s) with Target = 'Botulinum neurotoxin type E'
TargetBotulinum neurotoxin type E(Clostridium botulinum)
Brookhaven National Laboratory

Curated by ChEMBL
LigandPNGBDBM50189879(CHEMBL3827999)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of endopeptidase activity of Clostridium botulinum BoNT/E light chain using SNAP-25 as substrate after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBotulinum neurotoxin type E(Clostridium botulinum)
Brookhaven National Laboratory

Curated by ChEMBL
LigandPNGBDBM50189880(CHEMBL3828454)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of endopeptidase activity of Clostridium botulinum BoNT/E light chain using SNAP-25 as substrate after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBotulinum neurotoxin type E(Clostridium botulinum)
Brookhaven National Laboratory

Curated by ChEMBL
LigandPNGBDBM50189881(CHEMBL3827632)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of endopeptidase activity of Clostridium botulinum BoNT/E light chain using SNAP-25 as substrate after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBotulinum neurotoxin type E(Clostridium botulinum)
Brookhaven National Laboratory

Curated by ChEMBL
LigandPNGBDBM50322673(2'-(9H-fluoren-2-ylcarbamoyl)-4,4'-dichlorobipheny...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of endopeptidase activity of Clostridium botulinum BoNT/E light chain using SNAP-25 as substrate after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBotulinum neurotoxin type E(Clostridium botulinum)
Brookhaven National Laboratory

Curated by ChEMBL
LigandPNGBDBM50189882(CHEMBL3828595)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of endopeptidase activity of Clostridium botulinum BoNT/E light chain using SNAP-25 as substrate after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBotulinum neurotoxin type E(Clostridium botulinum)
Brookhaven National Laboratory

Curated by ChEMBL
LigandPNGBDBM50534915(CHEMBL4546947)
Affinity DataIC50:  1.42E+4nMAssay Description:Inhibition of Clostridium botulinum BoNT/E light chain using GFP-tagged VAMP2/SNAP-25 (Ala128 to Gly206 residues) as substrate after 15 mins by GFP b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBotulinum neurotoxin type E(Clostridium botulinum)
Brookhaven National Laboratory

Curated by ChEMBL
LigandPNGBDBM50534916(CHEMBL4441787)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of Clostridium botulinum BoNT/E light chain using GFP-tagged VAMP2/SNAP-25 (Ala128 to Gly206 residues) as substrate after 15 mins by GFP b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBotulinum neurotoxin type E(Clostridium botulinum)
Brookhaven National Laboratory

Curated by ChEMBL
LigandPNGBDBM50189883(CHEMBL1999371)
Affinity DataIC50:  4.85E+4nMAssay Description:Inhibition of Clostridium botulinum BoNT/E light chain using GFP-tagged VAMP2/SNAP-25 (Ala128 to Gly206 residues) as substrate after 15 mins by GFP b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBotulinum neurotoxin type E(Clostridium botulinum)
Brookhaven National Laboratory

Curated by ChEMBL
LigandPNGBDBM50189883(CHEMBL1999371)
Affinity DataKi:  1.29E+3nMAssay Description:Inhibition of protease activity of Clostridium botulinum BoNT/E light chain using SNAP-25 as substrate after 15 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBotulinum neurotoxin type E(Clostridium botulinum)
Brookhaven National Laboratory

Curated by ChEMBL
LigandPNGBDBM50189883(CHEMBL1999371)
Affinity DataKi:  1.29E+3nMAssay Description:Inhibition of protease activity of Clostridium botulinum BoNT/E using SNAP-25 as substrate after 15 mins by HPLC based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed