Found 532 Enz. Inhib. hit(s) with Target = 'Catenin beta-1' 
Affinity DataIC50: 13nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Affinity DataIC50: 28.5nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Affinity DataIC50: 38.5nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Affinity DataIC50: 183nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Affinity DataIC50: <300nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: <300nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: <300nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: <300nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: <300nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
TargetCatenin beta-1/Transcription factor 7-like 2(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human TCF4/ flag epitope-tagged beta-catenin (unknown origin) interaction transfected in human HCT116 cells after 24 hrs by beta-galact...More data for this Ligand-Target Pair
Affinity DataIC50: <300nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: <300nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: <300nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: <300nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 805nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Affinity DataIC50: 1.27E+3nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Affinity DataIC50: 1.39E+3nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant GST tagged beta catenin ARD by Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Affinity DataIC50: 2.57E+3nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of beta-catenin-mediated transcriptional activity in Wnt3a-stimulated human HeLa cells after 24 hrs by Dual-Glo luciferase reporter gene a...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of beta-catenin-mediated transcriptional activity in Wnt3a-stimulated human HeLa cells after 24 hrs by Dual-Glo luciferase reporter gene a...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after...More data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
TargetCatenin beta-1/Transcription factor 4(Homo sapiens (Human))
King Saud University
Curated by ChEMBL
King Saud University
Curated by ChEMBL
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human GST tagged Tcf4/beta catenin interaction after 2 hrs using fluorescent AP Attophos substrate by ELISA analysisMore data for this Ligand-Target Pair
