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Found 155 Enz. Inhib. hit(s) with Target = 'Cell division protein FtsZ'
TargetCell division protein FtsZ(Staphylococcus aureus)
Prolysis

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataIC50:  154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
TargetCell division protein FtsZ(Staphylococcus aureus)
Prolysis

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataIC50:  154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
TargetCell division protein FtsZ(Staphylococcus aureus)
Prolysis

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataIC50:  154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
TargetCell division protein FtsZ(Bacillus subtilis)
Shandong University

Curated by ChEMBL
LigandPNGBDBM25525(24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of FtsZ in Bacillus subtilis assessed as disruption of Z ring formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50203065(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)
Affinity DataIC50:  5.81E+3nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50335238(5-Benzamido-2-cyclohexyl-6-N,N-diethylamino-1H-ben...)
Affinity DataIC50:  6.21E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50203065(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)
Affinity DataIC50:  6.86E+3nMAssay Description:Inhibition of Escherichia coli FtsZ polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50335239(CHEMBL1651202 | butyl 2-cyclohexyl-6-(diethylamino...)
Affinity DataIC50:  7.69E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50079361(CHEMBL3416824)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50086108(CHEMBL3425702)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50439495(CHEMBL2418095)
Affinity DataIC50:  9.87E+3nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Aquifex aeolicus)
University Of Amsterdam

LigandPNGBDBM81331(MeGTP (6b))
Affinity DataIC50:  1.00E+4nM Kd:  3.33nMpH: 7.5Assay Description:The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant Escherichia coli K12 FtsZ assembly by light-scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50079359(Viriditoxin)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50079358(CHEMBL3416948)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of Escherichia coli FtsZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50079359(Viriditoxin)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of Escherichia coli FtsZ polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50079360(CHEBI:69681 | Dichamanetin)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM25525(24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11...)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of FtsZ in Escherichia coli assessed as disruption of Z ring formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50086088(CHEMBL3425706)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Aquifex aeolicus)
University Of Amsterdam

LigandPNGBDBM81332(PyrrGTP (7b))
Affinity DataIC50:  1.50E+4nM Kd:  15.6nMpH: 7.5Assay Description:The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Aquifex aeolicus)
University Of Amsterdam

LigandPNGBDBM81331(MeGTP (6b))
Affinity DataIC50:  1.53E+4nMpH: 7.5Assay Description:The binding affinities to FtsZ were determined by a fluorescent coupled assay for phosphate relase. In this GTPase studies, phosphate liberated durin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of recombinant Escherichia coli K12 FtsZ GTPase activity by malachite green sodium molybdate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50359406(CHEMBL1926717)
Affinity DataIC50:  1.64E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50359412(CHEMBL1926724)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50359407(CHEMBL1926719)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Aquifex aeolicus)
University Of Amsterdam

LigandPNGBDBM81332(PyrrGTP (7b))
Affinity DataIC50:  2.14E+4nMpH: 7.5Assay Description:The binding affinities to FtsZ were determined by a fluorescent coupled assay for phosphate relase. In this GTPase studies, phosphate liberated durin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50086098(CHEMBL3425705)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50086206(CHEMBL3425606)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Bacillus subtilis)
TBA

Curated by ChEMBL
LigandPNGBDBM50392993(TOTAROL)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of Bacillus subtilis FtsZ GTPase activity by enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50086123(CHEMBL3425694)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50359400(CHEMBL1929425)
Affinity DataIC50:  2.68E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50086124(CHEMBL3425693)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50359410(CHEMBL1926722)
Affinity DataIC50:  2.73E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50086201(CHEMBL3425611)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50359413(CHEMBL1926725)
Affinity DataIC50:  2.95E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50086200(CHEMBL3425612)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50086203(CHEMBL3425609)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Bacillus subtilis)
TBA

Curated by ChEMBL
LigandPNGBDBM50067040(((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of Bacillus subtilis FtsZ polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50359411(CHEMBL1926723)
Affinity DataIC50:  3.41E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50359398(CHEMBL110168)
Affinity DataIC50:  3.42E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50359401(CHEMBL1929426)
Affinity DataIC50:  3.43E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50359408(CHEMBL1926720)
Affinity DataIC50:  3.48E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Aquifex aeolicus)
University Of Amsterdam

LigandPNGBDBM81333(ClGTP (4b))
Affinity DataIC50:  3.50E+4nM Kd:  77nMpH: 7.5Assay Description:The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50:  3.60E+4nMpH: 6.5 T: 2°CAssay Description:The bacterial cytoskeletal protein FtsZ is a GTPase and has structural homology to the eukaryotic cytoskeletal protein tubulin, but lacks significant...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Aquifex aeolicus)
University Of Amsterdam

LigandPNGBDBM81335(BrGTP (5b))
Affinity DataIC50:  3.70E+4nM Kd:  126nMpH: 7.5Assay Description:The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Prolysis

Curated by ChEMBL
LigandPNGBDBM50201769(CHEMBL3416823)
Affinity DataIC50:  3.75E+4nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 N-terminal His6-tagged FtsZ GTPase activity expressed in Escherichia coli BL21(DE3) assessed as reduct...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Prolysis

Curated by ChEMBL
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of recombinant Staphylococcus aureus FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic pho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Prolysis

Curated by ChEMBL
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis)
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50359399(CHEMBL106808)
Affinity DataIC50:  3.81E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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