Compile Data Set for Download or QSAR
maximum 50k data
Found 1278 Enz. Inhib. hit(s) with Target = 'Coagulation factor V'
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50119052(Biotinylated E-76 peptide analogue | CHEMBL269354)
Affinity DataIC50:  1nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50119057(ALCDNPRIDRWYCQFVEG peptide analogue | Biotinylated...)
Affinity DataIC50:  1nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50119050(ALCDNPRIDRWYCQFVEG peptide analogue | Biotinylated...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Laboratory Of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326044((2S,5S,8R,11S,14S,17S,20S,23S,26R,29S,32S,35S,38S,...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity to tissue factor/factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50119049(Biotinylated E-76 peptide analogue | CHEMBL439285)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50167837(3-Amino-N-((R)-sec-butyl)-5-{1-[(4-carbamimidoyl-b...)
Affinity DataIC50:  1.70nMAssay Description:Inhibitory concentration against Coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50119048(Biotinylated E-76 peptide analogue | CHEMBL437872)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50127212(ALCDNPRIDRWYCQFVEG peptide analogue | CHEMBL237233...)
Affinity DataIC50:  1.90nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% rabbit serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50127214(ALCDNPRIDRWYCQFVEG peptide analogue | CHEMBL237233...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% rabbit serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50127212(ALCDNPRIDRWYCQFVEG peptide analogue | CHEMBL237233...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50127214(ALCDNPRIDRWYCQFVEG peptide analogue | CHEMBL237233...)
Affinity DataIC50:  2.40nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50119057(ALCDNPRIDRWYCQFVEG peptide analogue | Biotinylated...)
Affinity DataIC50:  2.5nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50119055(Biotinylated E-76 peptide analogue | CHEMBL414777)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50127213(ALCDNPRIDRWYCQFVEG peptide analogue | CHEMBL237234...)
Affinity DataIC50:  3.40nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% rabbit serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50119057(ALCDNPRIDRWYCQFVEG peptide analogue | Biotinylated...)
Affinity DataIC50:  3.60nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% rabbit serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50119056(Biotinylated E-76 peptide analogue | CHEMBL439444)
Affinity DataIC50:  4nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50127213(ALCDNPRIDRWYCQFVEG peptide analogue | CHEMBL237234...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50520865(CHEMBL4469752)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of human factor 7a preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM13592(2-{2-[(4-carbamimidoylphenyl)carbamoyl]-6-methoxyp...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50167830(3-amino-N-[(2R)-butan-2-yl]-5-[1-({[(4-carbamimido...)
Affinity DataIC50:  6.20nMAssay Description:Inhibitory concentration against Coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50439474(CHEMBL2417906)
Affinity DataIC50:  7nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM31501(substituted biphenyl derivative, 36ao)
Affinity DataIC50:  8nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Laboratory Of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50172214(6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...)
Affinity DataIC50:  8nMAssay Description:Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM31488(substituted biphenyl derivative, 36ab)
Affinity DataIC50:  9nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM31499(substituted biphenyl derivative, 36am)
Affinity DataIC50:  9nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM31497(substituted biphenyl derivative, 36ak)
Affinity DataIC50:  9nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM31468(substituted biphenyl derivative, 36h)
Affinity DataIC50:  9nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50439477(CHEMBL2417903)
Affinity DataIC50:  9nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM31462(substituted biphenyl derivative, 36b)
Affinity DataIC50:  9nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50119050(ALCDNPRIDRWYCQFVEG peptide analogue | Biotinylated...)
Affinity DataIC50:  9.20nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% rabbit serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50127212(ALCDNPRIDRWYCQFVEG peptide analogue | CHEMBL237233...)
Affinity DataIC50:  9.20nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% rabbit serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50167833(3-amino-N-[(2R)-butan-2-yl]-5-(1-{[({4-carbamimido...)
Affinity DataIC50:  9.40nMAssay Description:Inhibitory concentration against Coagulation factor VIIaMore data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50119050(ALCDNPRIDRWYCQFVEG peptide analogue | Biotinylated...)
Affinity DataIC50:  9.70nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50119047(Biotinylated E-76 peptide analogue | CHEMBL441926)
Affinity DataIC50:  10nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM31487(substituted biphenyl derivative, 36aa)
Affinity DataIC50:  10nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM31486(substituted biphenyl derivative, 36z)
Affinity DataIC50:  10nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Laboratory Of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50172213(6-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50520866(CHEMBL4469308)
Affinity DataIC50:  11nMAssay Description:Inhibition of human factor 7a preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50119050(ALCDNPRIDRWYCQFVEG peptide analogue | Biotinylated...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50439475(CHEMBL2417905)
Affinity DataIC50:  11nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM31493(substituted biphenyl derivative, 36ag)
Affinity DataIC50:  11nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM31470(substituted biphenyl derivative, 36j)
Affinity DataIC50:  11nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM31489(substituted biphenyl derivative, 36ac)
Affinity DataIC50:  11nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50439487(CHEMBL2417893)
Affinity DataIC50:  11nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50520867(CHEMBL4441346)
Affinity DataIC50:  12nMAssay Description:Inhibition of human factor 7a preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM31474(substituted biphenyl derivative, 36n)
Affinity DataIC50:  12nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50167836(3-amino-N-[(2R)-butan-2-yl]-5-(1-{[({4-carbamimido...)
Affinity DataIC50:  12nMAssay Description:Inhibitory concentration against Coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50119053(Biotinylated E-76 peptide analogue | CHEMBL415402)
Affinity DataIC50:  12nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50119054(Biotinylated E-76 peptide analogue | CHEMBL429011)
Affinity DataIC50:  13nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50119059(Biotinylated E-76 peptide analogue | CHEMBL410836)
Affinity DataIC50:  13nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 1278 total ) | Next | Last >>
Jump to: