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Found 44 Enz. Inhib. hit(s) with Target = 'MAPK/MAK/MRK overlapping kinase'
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human MOK (1 to 343 residues) using RSRSRSRSRSRSR as substrate incubated for 40 mins in presence of [gamma-33ATP by radiome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528521(US11192859, Compound 5)
Affinity DataKd:  4.10E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528522(US11192859, Compound 6)
Affinity DataKd:  9.90E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528523(US11192859, Compound 7)
Affinity DataKd:  7.70E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528524(US11192859, Compound 101)
Affinity DataKd:  4.30E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528525(US11192859, Compound 102)
Affinity DataKd:  2.90E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528526(US11192859, Compound 103)
Affinity DataKd:  1.80E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528527(US11192859, Compound 104)
Affinity DataKd:  6.00E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528528(US11192859, Compound 105)
Affinity DataKd:  4.50E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528530(US11192859, Compound 106)
Affinity DataKd:  3.40E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528532(US11192859, Compound 107)
Affinity DataKd:  4.40E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528533(US11192859, Compound 108)
Affinity DataKd:  1.10E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528534(US11192859, Compound 109)
Affinity DataKd:  1.90E+3nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528535(US11192859, Compound 214)
Affinity DataKd:  34nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528536(US11192859, Compound 215)
Affinity DataKd:  27nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528537(US11192859, Compound 218)
Affinity DataKd:  80nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528538(US11192859, Compound 219)
Affinity DataKd:  89nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528539(US11192859, Compound 220)
Affinity DataKd:  22nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528540(US11192859, Compound 221)
Affinity DataKd:  34nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528541(US11192859, Compound 222)
Affinity DataKd:  32nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528542(US11192859, Compound 223)
Affinity DataKd:  72nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528543(US11192859, Compound 224)
Affinity DataKd:  32nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528544(US11192859, Compound 225)
Affinity DataKd:  122nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528545(US11192859, Compound 226)
Affinity DataKd:  25nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528546(US11192859, Compound 227)
Affinity DataKd:  10nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528547(US11192859, Compound 228)
Affinity DataKd:  122nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528548(US11192859, Compound 229)
Affinity DataKd:  3nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528549(US11192859, Compound 231)
Affinity DataKd:  47nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528550(US11192859, Compound 235)
Affinity DataKd:  76nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528551(US11192859, Compound 236)
Affinity DataKd:  56nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528552(US11192859, Compound 238)
Affinity DataKd:  16nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528553(US11192859, Compound 239)
Affinity DataKd:  13nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528554(US11192859, Compound 241)
Affinity DataKd:  11nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528555(US11192859, Compound 242)
Affinity DataKd:  8nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528556(US11192859, Compound 244)
Affinity DataKd:  54nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528557(US11192859, Compound 247)
Affinity DataKd:  2nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528558(US11192859, Compound 250)
Affinity DataKd:  81nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528559(US11192859, Compound 251)
Affinity DataKd:  168nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528560(US11192859, Compound 252)
Affinity DataKd:  29nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528561(US11192859, Compound 253)
Affinity DataKd:  1.30E+3nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528562(US11192859, Compound 254)
Affinity DataKd:  1.34E+3nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528563(US11192859, Compound 255)
Affinity DataKd:  137nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528564(US11192859, Compound 256)
Affinity DataKd:  5.80E+3nMAssay Description:Table 4: Native tryptophan fluorescence experiments were conducted using a Horiba Jobin Yvon Fluorolog spectrofluorometer. 1 mM of compound was disso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAPK/MAK/MRK overlapping kinase(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM528520(US11192859, Compound 4)
Affinity DataKd:  5.60E+4nMAssay Description:Table 2-3: Step 1. Add 50 μl anti-DIAPH1 (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C. Day 2 Step 2. Us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent