Found 1108 Enz. Inhib. hit(s) with Target = 'Nuclear factor erythroid 2-related factor 2' TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Inhibition of full length Flag/His-tagged Keap1 kelch domain (unknown origin)/full length Avi-tagged Nrf2 (unknown origin) interaction after 2.25 hrs...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Keap1 kelch domain (unknow origin)/Nrf2-ETGE peptide (unknown origin) interaction by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of full length Flag/His-tagged Keap1 kelch domain (unknown origin)/full length Avi-tagged Nrf2 (unknown origin) interaction after 2.25 hrs...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of Keap1 Kelch domain/FITC-9mer Nrf2 (unknown origin) interaction after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of Keap1 Kelch domain/FITC-9mer Nrf2 (unknown origin) interaction after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of Keap1/Nrf2 (unknown origin) interaction assessed as displacement of FITC-betaAla-DEETGEF-OH from Keap1 Kelch domain after 1 hr by FITC-...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of Keap1 Kelch domain (unknown origin) /Nrf2 (unknown origin) interaction using fluorescein-labeled 9-mer peptide containing NRF2 Neh2 dom...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of NRF2 in human MDA-MB-231 cells harboring ARE-GFP-Luc assessed as reduction in ARE-luciferase activity after 16 hrs by firefly luciferas...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of Keap1/Nrf2 complex (unknown origin)More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cellsMore data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of Keap1 Kelch domain (unknown origin) /Nrf2 (unknown origin) interaction using fluorescein-labeled 9-mer peptide containing NRF2 Neh2 dom...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Concentration required to inhibit the phosphorylation of a 14-residue fragment of phospholipase C gamma 1 by Epidermal growth factor receptor from A4...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of Keap1 Kelch domain (unknown origin) /Nrf2 (unknown origin) interaction using fluorescein-labeled 9-mer peptide containing NRF2 Neh2 dom...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cellsMore data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) protein-protein interactionMore data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 101nMAssay Description:Inhibition of Keap1 Kelch domain (unknown origin) /Nrf2 (unknown origin) interaction using fluorescein-labeled 9-mer peptide containing NRF2 Neh2 dom...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Inhibition of Nrf2 (unknown origin)More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 118nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cellsMore data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 122nMAssay Description:Inhibition of Keap1 Kelch domain-Nrf2 ETGE (unknown origin) protein-protein interaction incubated for 30 mins by fluorescence polarization competitio...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cellsMore data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 144nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 146nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 149nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant GST-His-tagged Keap1-DC domain (321 to 609 residues) (unknown origin) expressed in Escherichia coli/FAM-labeled Nrf2 (unkno...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) protein-protein interactionMore data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) protein-protein interactionMore data for this Ligand-Target Pair
