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Found 1986 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 2'
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM50594500(CHEMBL5202979)
Affinity DataIC50:  3.70nMAssay Description:Agonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM50257829(2-(4-amino-5-(5-iodo-2-isopropyl-4-methoxyphenoxy)...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at human P2X2/3 receptor expressed in 1321n1c cells by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM50594498(CHEMBL4583478)
Affinity DataIC50:  8.30nMAssay Description:Agonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM50413370(CHEMBL495204)
Affinity DataIC50:  13nMAssay Description:Inhibition of P2X2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM320093(3-(5-ethyl-1,3- thiazol-2-yl)-5- [(3R)- tetrahydro...)
Affinity DataIC50:  14nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319936(3-[(2- Methylpyridin- 4-yl)oxy]-5- (5-methyl- 1,3-...)
Affinity DataIC50:  14nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319936(3-[(2- Methylpyridin- 4-yl)oxy]-5- (5-methyl- 1,3-...)
Affinity DataIC50:  14nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319936(3-[(2- Methylpyridin- 4-yl)oxy]-5- (5-methyl- 1,3-...)
Affinity DataIC50:  14nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319936(3-[(2- Methylpyridin- 4-yl)oxy]-5- (5-methyl- 1,3-...)
Affinity DataIC50:  14nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM320093(3-(5-ethyl-1,3- thiazol-2-yl)-5- [(3R)- tetrahydro...)
Affinity DataIC50:  14nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM320093(3-(5-ethyl-1,3- thiazol-2-yl)-5- [(3R)- tetrahydro...)
Affinity DataIC50:  14nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM320093(3-(5-ethyl-1,3- thiazol-2-yl)-5- [(3R)- tetrahydro...)
Affinity DataIC50:  14nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319933(N-[(1R)-1-(6- Methyl- pyridazin-3- yl)ethyl]-3- [(...)
Affinity DataIC50:  16nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM50413367(CHEMBL523173)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at human P2X2/3 receptor expressed in 1321n1c cells by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM50413364(CHEMBL492300)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at human P2X2/3 receptor expressed in 1321n1c cells by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319933(N-[(1R)-1-(6- Methyl- pyridazin-3- yl)ethyl]-3- [(...)
Affinity DataIC50:  16nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319933(N-[(1R)-1-(6- Methyl- pyridazin-3- yl)ethyl]-3- [(...)
Affinity DataIC50:  16nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319933(N-[(1R)-1-(6- Methyl- pyridazin-3- yl)ethyl]-3- [(...)
Affinity DataIC50:  16nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319940(N-[(1R)-1-(6- Methylpyridin- 3-yl)ethyl]- 3-[(2- m...)
Affinity DataIC50:  17nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319940(N-[(1R)-1-(6- Methylpyridin- 3-yl)ethyl]- 3-[(2- m...)
Affinity DataIC50:  17nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319940(N-[(1R)-1-(6- Methylpyridin- 3-yl)ethyl]- 3-[(2- m...)
Affinity DataIC50:  17nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319940(N-[(1R)-1-(6- Methylpyridin- 3-yl)ethyl]- 3-[(2- m...)
Affinity DataIC50:  17nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319931(3-(5-Methyl- 1,3-thiazol-2- yl)-5- (tetrahydro- 2H...)
Affinity DataIC50:  19nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319931(3-(5-Methyl- 1,3-thiazol-2- yl)-5- (tetrahydro- 2H...)
Affinity DataIC50:  19nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319931(3-(5-Methyl- 1,3-thiazol-2- yl)-5- (tetrahydro- 2H...)
Affinity DataIC50:  19nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319931(3-(5-Methyl- 1,3-thiazol-2- yl)-5- (tetrahydro- 2H...)
Affinity DataIC50:  19nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM320075(3-(5-ethyl-1,3- thiazol-2-yl)-5- [(3R)- tetrahydro...)
Affinity DataIC50:  22nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM320075(3-(5-ethyl-1,3- thiazol-2-yl)-5- [(3R)- tetrahydro...)
Affinity DataIC50:  22nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM320075(3-(5-ethyl-1,3- thiazol-2-yl)-5- [(3R)- tetrahydro...)
Affinity DataIC50:  22nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM320075(3-(5-ethyl-1,3- thiazol-2-yl)-5- [(3R)- tetrahydro...)
Affinity DataIC50:  22nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM320111(3-(5-ethyl-1,3- thiazol-2-yl)-5- [(3S)- tetrahydro...)
Affinity DataIC50:  23nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM320111(3-(5-ethyl-1,3- thiazol-2-yl)-5- [(3S)- tetrahydro...)
Affinity DataIC50:  23nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM320102(3-(5-ethyl-1,3- thiazol-2-yl)-5- [(2R)- tetrahydro...)
Affinity DataIC50:  23nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM320111(3-(5-ethyl-1,3- thiazol-2-yl)-5- [(3S)- tetrahydro...)
Affinity DataIC50:  23nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM50413345(CHEMBL494159)
Affinity DataIC50:  25nMAssay Description:Antagonist activity at human P2X2/3 receptor expressed in 1321n1c cells by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319932(N-[(1R)-1-(6- Methyl- pyridazin-3- yl)ethyl]-3- (5...)
Affinity DataIC50:  27nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM320137(3-{[1-(2,2- difluoroethyl) piperidin-4-yl]oxy}- 5-...)
Affinity DataIC50:  27nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319958(3-(5-Ethyl-1,3-thiazol-2-yl)-N-[(1R)-1-(2-methylpy...)
Affinity DataIC50:  27nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319932(N-[(1R)-1-(6- Methyl- pyridazin-3- yl)ethyl]-3- (5...)
Affinity DataIC50:  27nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM320137(3-{[1-(2,2- difluoroethyl) piperidin-4-yl]oxy}- 5-...)
Affinity DataIC50:  27nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM320137(3-{[1-(2,2- difluoroethyl) piperidin-4-yl]oxy}- 5-...)
Affinity DataIC50:  27nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319932(N-[(1R)-1-(6- Methyl- pyridazin-3- yl)ethyl]-3- (5...)
Affinity DataIC50:  27nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319958(3-(5-Ethyl-1,3-thiazol-2-yl)-N-[(1R)-1-(2-methylpy...)
Affinity DataIC50:  27nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM320137(3-{[1-(2,2- difluoroethyl) piperidin-4-yl]oxy}- 5-...)
Affinity DataIC50:  27nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319958(3-(5-Ethyl-1,3-thiazol-2-yl)-N-[(1R)-1-(2-methylpy...)
Affinity DataIC50:  27nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319932(N-[(1R)-1-(6- Methyl- pyridazin-3- yl)ethyl]-3- (5...)
Affinity DataIC50:  27nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM319958(3-(5-Ethyl-1,3-thiazol-2-yl)-N-[(1R)-1-(2-methylpy...)
Affinity DataIC50:  27nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM320217(3-{[4,4-difluoro-1-methylpiperidin-3-yl]methoxy}-5...)
Affinity DataIC50:  28nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM320217(3-{[4,4-difluoro-1-methylpiperidin-3-yl]methoxy}-5...)
Affinity DataIC50:  28nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandPNGBDBM322574(US10183937, Example 385 | US10202369, Example 385)
Affinity DataIC50:  28nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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