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Found 44 Enz. Inhib. hit(s) with Target = 'Phospholipase A-2-activating protein'
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50042034((5Z)-7-Oxozeaenol | 5Z-7-Oxozeaenol | CHEBI:67559 ...)
Affinity DataIC50:  11nMAssay Description:Inhibition of TNFalpha-PLAP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50245461(CHEMBL4068569)
Affinity DataIC50:  36nMAssay Description:Inhibition of TNFalpha-PLAP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM41890(2-(1-benzimidazolyl)-1-(3,4-dihydroxyphenyl)ethano...)
Affinity DataIC50:  800nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM41891(1-(3,4-dihydroxyphenyl)-2-(2-methyl-1-benzimidazol...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM41891(1-(3,4-dihydroxyphenyl)-2-(2-methyl-1-benzimidazol...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50237956(1-(3,4-dihydroxyphenyl)-2-(1-(4-methoxyphenyl)-1H-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM41887(1-(3,4-dihydroxyphenyl)-2-(1-imidazolyl)ethanone;h...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50309563(2-(2-(3,4-dihydroxyphenyl)-2-oxoethylthio)-4-(meth...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50309564(1-(3,4-dihydroxyphenyl)-2-(4,6-dimethylpyrimidin-2...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50309565(1-(3,4-dihydroxyphenyl)-2-(4-methyl-1H-pyrazol-1-y...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50309567(3-(2-(3,4-dihydroxyphenyl)-2-oxoethyl)-6,7-dimetho...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM41889(1-(3,4-dihydroxyphenyl)-2-(2-methyl-1-imidazolyl)e...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM41889(1-(3,4-dihydroxyphenyl)-2-(2-methyl-1-imidazolyl)e...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM41888(1-(3,4-dihydroxyphenyl)-2-(2-ethyl-1-imidazolyl)et...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM41888(1-(3,4-dihydroxyphenyl)-2-(2-ethyl-1-imidazolyl)et...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM46047(1-[3,4-bis(oxidanyl)phenyl]-2-(4-bromanyl-2-methyl...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50309588(CHEMBL589752 | L-homoarginine)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM18073((2S)-2-amino-3-phenylpropanoic acid | CHEMBL301523...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM10847(1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dion...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50241179((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM21974((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50219348((2S)-2-amino-4-methylpentanoic acid | (S)-(+)-leuc...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50309587(CHEMBL598548 | L-leucinamide | LEUCINE AMIDE)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM46053(1-(3,4-dihydroxyphenyl)-2-(4-methyl-1-imidazolyl)e...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM46052(1-(3,4-dihydroxyphenyl)-2-(5,6-dimethyl-1-benzimid...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50309570(1-(3,4-dihydroxyphenyl)-2-(4-methyl-5-phenyl-4H-1,...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM46050(2-(1H-benzimidazol-2-ylamino)-1-(3,4-dihydroxyphen...)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50245475(CHEMBL4103122)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TNFalpha-PLAP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50245474(CHEMBL4078847)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TNFalpha-PLAP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM46051(1-(3,4-dihydroxyphenyl)-2-(1,2,4-triazol-4-yl)etha...)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM46048(1-[3,4-bis(oxidanyl)phenyl]-2-(4-bromanylimidazol-...)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM46049(1-(3,4-dihydroxyphenyl)-2-(2-phenyl-1-imidazolyl)e...)
Affinity DataIC50:  1.72E+4nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM46041(1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanone...)
Affinity DataIC50:  3.93E+4nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50309578(4-((4,6-dimethylpyrimidin-2-ylamino)methyl)benzene...)
Affinity DataIC50:  5.12E+4nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50309580(2-(4,6-dimethylpyrimidin-2-ylthio)-1-(3-hydroxyphe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50309579(2-(4,6-dimethylpyrimidin-2-ylthio)-1-(4-hydroxyphe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50299523(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PLAP by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50309585(CHEMBL599678 | N-(3,4-dihydroxyphenethyl)-4,5-dime...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM46046(2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-1-(3-methox...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM46045(1-(1,3-benzodioxol-5-yl)-2-(4,6-dimethylpyrimidin-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50309583(2-(4,6-dimethylpyrimidin-2-ylthio)-1-(4-methoxyphe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50309584(CHEMBL599476 | N-(3,4-dihydroxybenzyl)-4,5-dimethy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM32012(1-(3,4-Dihydroxy-phenyl)-2-(5-phenyl-4H-[1,2,4]tri...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A-2-activating protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50309586(2-(5-(3-aminophenyl)-4-methyl-4H-1,2,4-triazol-3-y...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PLAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed