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Found 104 Enz. Inhib. hit(s) with Target = 'Aldehyde oxidase'
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataKi:  0.870nMAssay Description:Uncompetitive type inhibition of human AOX assessed as inhibition constant using vanillin as substrate by HPLC-MS analysisMore data for this Ligand-Target Pair
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataKi:  0.870nMAssay Description:Uncompetitive type inhibition of human AOX assessed as inhibition constant using phthalazine as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataKi:  0.870nMAssay Description:Uncompetitive inhibition of human liver cytosolic aldehyde oxidase using phthalazine as substrate assessed as enzyme-substrate complex by Lineweaver-...More data for this Ligand-Target Pair
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataKi:  0.870nMAssay Description:Uncompetitive type inhibition of human AOX assessed as inhibition constant using nicotine-1(S)-iminium ion as substrate incubated for 2 mins by HPLC-...More data for this Ligand-Target Pair
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataKi:  2.30nMAssay Description:Competitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as free enzyme by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetAldehyde oxidase 1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM82507((+/-)-Methadone | CAS_5967-73-7 | METHADONE | Meth...)
Affinity DataKi:  30nMAssay Description:Inhibition of rat aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase 1(Oryctolagus cuniculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM87351(Amsacrine hydrochloride | CHEMBL43 | MLS002153376 ...)
Affinity DataKi:  60nMAssay Description:Inhibition of rabbit aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM50187243(17-ethinyl-3,17-estradiol | 17-ethinyl-3,17-oestra...)
Affinity DataKi:  430nMAssay Description:Competitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as free enzyme by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM24778(2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...)
Affinity DataKi:  470nMAssay Description:Competitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as free enzyme by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  620nMAssay Description:Competitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as free enzyme by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataKi:  870nMAssay Description:Competitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as free enzyme by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM50241107(1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazo...)
Affinity DataKi:  1.20E+3nMAssay Description:Competitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as free enzyme by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM24778(2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...)
Affinity DataKi:  1.50E+3nMAssay Description:Uncompetitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as enzyme-substrate complex by Lineweaver-Burk pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAldehyde oxidase 1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of rat aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase 1(Oryctolagus cuniculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332779(6,6'-azopurine | CHEMBL1630858)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of rabbit aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM50187243(17-ethinyl-3,17-estradiol | 17-ethinyl-3,17-oestra...)
Affinity DataKi:  3.60E+3nMAssay Description:Uncompetitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as enzyme-substrate complex by Lineweaver-Burk pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataKi:  4.40E+3nMAssay Description:Uncompetitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as enzyme-substrate complex by Lineweaver-Burk pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase 1(Cavia porcellus (Guinea pig))
Kermanshah University Of Medical Sciences

LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)
Affinity DataKi:  4.53E+3nM IC50:  1.45E+4nMpH: 7.0Assay Description:Guinea pig AO activity was assayed spectrophotometrically using phenanthridine as a substrate at 322 nm. All spectrophotometric determinations were c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  5.10E+3nMAssay Description:Competitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as free enzyme by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase 1(Cavia porcellus (Guinea pig))
Kermanshah University Of Medical Sciences

LigandPNGBDBM24778(2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...)
Affinity DataKi:  7.23E+3nM IC50:  3.18E+4nMpH: 7.0Assay Description:Guinea pig AO activity was assayed spectrophotometrically using phenanthridine as a substrate at 322 nm. All spectrophotometric determinations were c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM50366979(PYRIDOXAL)
Affinity DataKi:  3.00E+4nMAssay Description:Tested for its ability to inhibit rabbit liver aldehyde oxidase catalyzed oxidation of N-methyl-nicotinamide (NMN)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase 1(Cavia porcellus (Guinea pig))
Kermanshah University Of Medical Sciences

LigandPNGBDBM175349(4'-Isopropyl Benzofuranone (4'-CH(CH3)2) |...)
Affinity DataKi:  4.80E+4nM IC50:  4.94E+4nMpH: 7.0Assay Description:Guinea pig AO activity was assayed spectrophotometrically using phenanthridine as a substrate at 322 nm. All spectrophotometric determinations were c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde oxidase 1(Cavia porcellus (Guinea pig))
Kermanshah University Of Medical Sciences

LigandPNGBDBM175350(2',3',4'-three-Hydroxyl Benzofuranone ...)
Affinity DataKi:  7.21E+4nM IC50:  6.57E+4nMpH: 7.0Assay Description:Guinea pig AO activity was assayed spectrophotometrically using phenanthridine as a substrate at 322 nm. All spectrophotometric determinations were c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM86521(CAS_5719 | NSC_5719 | Zaleplon)
Affinity DataKi:  8.30E+4nMAssay Description:Inhibition of aldehyde oxidase in human liver cytosol assessed as production of oxozoniporideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM50366978(CHEMBL103375)
Affinity DataKi:  1.00E+5nMAssay Description:Tested for its ability to inhibit rabbit liver aldehyde oxidase catalyzed oxidation of N-methyl-nicotinamide (NMN)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase 1(Cavia porcellus (Guinea pig))
Kermanshah University Of Medical Sciences

LigandPNGBDBM175351(3',4',5'-three-Hydroxyl Benzofuranone ...)
Affinity DataKi:  1.34E+5nMpH: 7.0Assay Description:Guinea pig AO activity was assayed spectrophotometrically using phenanthridine as a substrate at 322 nm. All spectrophotometric determinations were c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase 1(Cavia porcellus (Guinea pig))
Kermanshah University Of Medical Sciences

LigandPNGBDBM175347(2',4'-di-Hydroxy Benzofuranone (2',4&#...)
Affinity DataKi:  1.40E+5nM IC50:  2.01E+5nMpH: 7.0Assay Description:Guinea pig AO activity was assayed spectrophotometrically using phenanthridine as a substrate at 322 nm. All spectrophotometric determinations were c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase 1(Cavia porcellus (Guinea pig))
Kermanshah University Of Medical Sciences

LigandPNGBDBM19461(α-CA inhibitor, 5 | 5,7-dihydroxy-2-(4-hydrox...)
Affinity DataKi:  1.48E+5nM IC50:  2.12E+5nMpH: 7.0Assay Description:Guinea pig AO activity was assayed spectrophotometrically using phenanthridine as a substrate at 322 nm. All spectrophotometric determinations were c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM22889((Cimetidine) N-Methyl-N''''-[2-(5-methyl-1H-imidaz...)
Affinity DataKi:  1.55E+5nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase 1(Cavia porcellus (Guinea pig))
Kermanshah University Of Medical Sciences

LigandPNGBDBM175348(2',5'-di-Hydroxy Benzofuranone (2',5&#...)
Affinity DataKi:  1.60E+5nM IC50:  1.15E+5nMpH: 7.0Assay Description:Guinea pig AO activity was assayed spectrophotometrically using phenanthridine as a substrate at 322 nm. All spectrophotometric determinations were c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase 1(Cavia porcellus (Guinea pig))
Kermanshah University Of Medical Sciences

LigandPNGBDBM175345(4'-Nitro Benzofuranone (4'-NO2) | 6-Hydrox...)
Affinity DataKi:  1.60E+5nM IC50:  1.71E+5nMpH: 7.0Assay Description:Guinea pig AO activity was assayed spectrophotometrically using phenanthridine as a substrate at 322 nm. All spectrophotometric determinations were c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM50366976(CHEMBL102691)
Affinity DataKi:  2.00E+5nMAssay Description:Tested for its ability to inhibit rabbit liver aldehyde oxidase catalyzed oxidation of N-methyl-nicotinamide (NMN)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM50366982(CHEMBL316980)
Affinity DataKi:  2.00E+5nMAssay Description:Tested for its ability to inhibit rabbit liver aldehyde oxidase catalyzed oxidation of N-methyl-nicotinamide (NMN)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase 1(Cavia porcellus (Guinea pig))
Kermanshah University Of Medical Sciences

LigandPNGBDBM175344(2'-Nitro Benzofuranone (2'-NO2) | 6-Hydrox...)
Affinity DataKi:  2.53E+5nM IC50:  1.93E+5nMpH: 7.0Assay Description:Guinea pig AO activity was assayed spectrophotometrically using phenanthridine as a substrate at 322 nm. All spectrophotometric determinations were c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM50366980(CHEMBL318466)
Affinity DataKi:  3.00E+5nMAssay Description:Tested for its ability to inhibit rabbit liver aldehyde oxidase catalyzed oxidation of N-methyl-nicotinamide (NMN)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM50366977(CHEMBL103253)
Affinity DataKi:  3.00E+5nMAssay Description:Tested for its ability to inhibit rabbit liver aldehyde oxidase catalyzed oxidation of N-methyl-nicotinamide (NMN)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM50366981(CHEMBL318547)
Affinity DataKi:  4.00E+5nMAssay Description:Tested for its ability to inhibit rabbit liver aldehyde oxidase catalyzed oxidation of N-methyl-nicotinamide (NMN)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase 1(Cavia porcellus (Guinea pig))
Kermanshah University Of Medical Sciences

LigandPNGBDBM175346(2'-Hydroxy Benzofuranone (2'-OH) | 6-Hydro...)
Affinity DataKi:  4.42E+5nMpH: 7.0Assay Description:Guinea pig AO activity was assayed spectrophotometrically using phenanthridine as a substrate at 322 nm. All spectrophotometric determinations were c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM50366975(CHEMBL105079)
Affinity DataKi:  1.50E+6nMAssay Description:Tested for its ability to inhibit rabbit liver aldehyde oxidase catalyzed oxidation of N-methyl-nicotinamide (NMN)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataIC50:  8nMAssay Description:Inhibition of Homo sapiens (human) aldehyde oxidaseMore data for this Ligand-Target Pair
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM50332780(7-Hydroxy-acridine-4-carboxylic acid (2-dimethylam...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase 1(Macaca fascicularis)
Pfizer

Curated by ChEMBL
LigandPNGBDBM24778(2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...)
Affinity DataIC50:  110nMAssay Description:Inhibition of monkey aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase 1(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM24778(2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...)
Affinity DataIC50:  150nMAssay Description:Inhibition of mouse aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase 1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM24778(2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...)
Affinity DataIC50:  190nMAssay Description:Inhibition of rat aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde oxidase(Homo sapiens (Human))
Nova University Lisbon

Curated by ChEMBL
LigandPNGBDBM24778(2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAldehyde oxidase 1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332780(7-Hydroxy-acridine-4-carboxylic acid (2-dimethylam...)
Affinity DataIC50:  320nMAssay Description:Inhibition of rat aldehyde oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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