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Found 50 Enz. Inhib. hit(s) with Target = 'Ectonucleoside triphosphate diphosphohydrolase 2'
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50262249(4-[2-((2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimi...)
Affinity DataKi:  8.20E+3nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rattus norvegicus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50227019(CHEMBL271673 | sodium 1-amino-4-(4-chlorophenylami...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of rat NTPDase2 expressed in CHO cells using ATP as substrate incubated for 10 mins by UV absorbance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rattus norvegicus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50378649(CHEMBL597197)
Affinity DataKi:  1.91E+4nMAssay Description:Inhibition of rat NTPDase2 expressed in CHO cells using ATP as substrate incubated for 10 mins by UV absorbance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50048062(CHEMBL3314932)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of recombinant human NTPDase2 transfected in COS-7 cells using ATP substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rattus norvegicus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50552129(CHEMBL4744335)
Affinity DataKi:  2.42E+4nMAssay Description:Inhibition of rat NTPDase2 expressed in CHO cells using ATP as substrate incubated for 10 mins by UV absorbance methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rattus norvegicus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50029031(1-Amino-4-{4-[4-chloro-6-(3-sulfo-phenylamino)-[1,...)
Affinity DataKi:  2.42E+4nMAssay Description:Inhibition of rat NTPDase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rattus norvegicus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50029031(1-Amino-4-{4-[4-chloro-6-(3-sulfo-phenylamino)-[1,...)
Affinity DataKi:  2.42E+4nMAssay Description:Inhibition of rat recombinant NTPDase2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rattus norvegicus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50029031(1-Amino-4-{4-[4-chloro-6-(3-sulfo-phenylamino)-[1,...)
Affinity DataKi:  2.42E+4nMAssay Description:Inhibition of rat NTPdase2 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50262311(4-[(2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin...)
Affinity DataKi:  2.92E+4nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rattus norvegicus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50227032(CHEMBL256057 | acid blue 25 | sodium 1-amino-9,10-...)
Affinity DataKi:  3.58E+4nMAssay Description:Inhibition of rat NTPdase2 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rattus norvegicus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50262422(CHEMBL477339 | sodium (E)-4-((3-formyl-4-hydroxy-5...)
Affinity DataKi:  4.42E+4nMAssay Description:Inhibition of rat NTPDase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rattus norvegicus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)
Affinity DataKi:  6.54E+4nMAssay Description:Inhibition of rat NTPDase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rattus norvegicus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)
Affinity DataKi:  6.54E+4nMAssay Description:Inhibition of rat recombinant NTPDase2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50262252(2-[(2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin...)
Affinity DataKi:  7.17E+4nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50262312(2-[2-((2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimi...)
Affinity DataKi:  1.16E+5nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50262310(3-[(2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin...)
Affinity DataKi:  1.67E+5nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50262250(4-[3-((2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimi...)
Affinity DataKi:  1.73E+5nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50307835(CHEMBL590956 | Sodium 1-amino-4-[4-fluoro-2-carbox...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of human NTPdase2 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50307836(CHEMBL608559 | Sodium 1-Amino-4-(2-anthracenylamin...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of human NTPdase2 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50268725(CHEMBL496030 | sodium 1-amino-4-(4-hydroxyphenylam...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of human NTPdase2 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50262251(4-[4-((2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimi...)
Affinity DataKi:  2.10E+5nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50262373(4-[4-((2S,3R,4S,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-...)
Affinity DataKi:  2.13E+5nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rattus norvegicus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50268574(CHEMBL498423 | Sodium 1-Amino-4-(1-naphthylamino)-...)
Affinity DataKi: >4.00E+5nMAssay Description:Inhibition of rat NTPdase2 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50262372(4-[3-((2S,3R,4S,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-...)
Affinity DataKi:  1.44E+6nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50546288(CHEMBL4743437)
Affinity DataIC50: >10nMAssay Description:Inhibition of NTPDase 2 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50546280(CHEMBL4761506)
Affinity DataIC50: >10nMAssay Description:Inhibition of NTPDase 2 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50: >10nMAssay Description:Inhibition of NTPDase 2 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50187685(CHEMBL597418)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant human NTPDase2 expressed in CHO cells using ADP as substrate incubated for 10 mins by capillary electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50552128(CHEMBL4787368)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human NTPDase2 expressed in green monkey Cos-7 cells using ATP as substrate preincubated for 3 mins followed by substrate addition by m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50561221(CHEMBL4745473 | US11377469, Example 95)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human NTPDase-2 expressed in CHO-K1 cells in presence of DNA/LTX mixtureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50527649(CHEMBL4467828)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human NTPDase 2 expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measured after 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of human NTPDase2 expressed in green monkey Cos-7 cells using ATP as substrate preincubated for 3 mins followed by substrate addition by m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50:  2.41E+4nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50048062(CHEMBL3314932)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of recombinant human NTPDase2 transfected in COS-7 cells using ATP substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50262249(4-[2-((2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimi...)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cells assessed as residual activity by capillary electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50262311(4-[(2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin...)
Affinity DataIC50:  1.01E+5nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cells assessed as residual activity by capillary electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50276791(CHEMBL4164891)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50276780(CHEMBL4172933)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50276781(CHEMBL4159729)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50276790(CHEMBL4174849)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50276794(CHEMBL4161473)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50276786(CHEMBL4172790)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50276787(CHEMBL4173693)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50276785(CHEMBL4164185)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50276789(CHEMBL4175913)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50276788(CHEMBL4162261)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50276782(CHEMBL4165654)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50276784(CHEMBL4159530)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50276783(CHEMBL4169839)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50262252(2-[(2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin...)
Affinity DataIC50:  3.74E+5nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cells assessed as residual activity by capillary electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed