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Found 1031 Enz. Inhib. hit(s) with Target = 'Bcl-2-related protein A1'
TargetBcl-2-related protein A1 [1-149](Homo sapiens (Human))
University Of California Riverside

LigandPNGBDBM218795(130E7 | Ac-λIAQELRRIGDEFNAYYARR-NH2)
Affinity DataKd:  2.60nMpH: 7.4 T: 2°CAssay Description:One hundred microliters of a 600 ng/mL solution of biotin-BID (Biotin-lc-EDIIRNIARHLAQVGDSMDR-NH2, where lc indicates a hydrocarbon chain of six meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604885(CHEMBL5177177)
Affinity DataKd:  262nMAssay Description:Binding affinity to His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511123(CHEMBL4522193)
Affinity DataKd:  920nMAssay Description:Binding affinity to immobilized biotin-labeled and N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity for GST-tagged human BCL2A1 expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM21400(CHEMBL192571 | N-[(4-{[(2R)-4-(dimethylamino)-1-(p...)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity for GST-tagged human BCL2A1 expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511138(CHEMBL4576854)
Affinity DataKd:  1.27E+3nMAssay Description:Binding affinity to immobilized biotin-labeled and N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50576622(CHEMBL4850731)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length BCL2A1 (M1 to G153 residues) expressed in bacterial expression system by BCL2SCAN assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50210070(CHEMBL3883565)
Affinity DataKi: <0.100nMAssay Description:Inhibition of FITC-betaA-DIIRNIARHLAQVGDSMRSI-NH2 binding to recombinant human Bcl2A1 (1 to 152 residues) BH3 binding site expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50558851(CHEMBL4782684)
Affinity DataKi:  10nMAssay Description:Covalent binding affinity to human Bcl2A1 by FBid based FP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50558852(CHEMBL4747465)
Affinity DataKi:  31nMAssay Description:Covalent binding affinity to human Bcl2A1 by FBid based FP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50210069(CHEMBL3884841)
Affinity DataKi:  32nMAssay Description:Inhibition of FITC-betaA-DIIRNIARHLAQVGDSMRSI-NH2 binding to recombinant human Bcl2A1 (1 to 152 residues) BH3 binding site expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50558857(CHEMBL4752520)
Affinity DataKi:  47nMAssay Description:Covalent binding affinity to human Bcl2A1 by FBid based FP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50558854(CHEMBL4755711)
Affinity DataKi:  82nMAssay Description:Covalent binding affinity to human Bcl2A1 by FBid based FP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511123(CHEMBL4522193)
Affinity DataKi:  84nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511138(CHEMBL4576854)
Affinity DataKi:  100nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from His-tagged human BFL-1 (1 to 151 residues) expressed in Escherichia coli BL21 (DE3) assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511138(CHEMBL4576854)
Affinity DataKi:  100nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511124(CHEMBL4533559)
Affinity DataKi:  100nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50558856(CHEMBL4791348)
Affinity DataKi:  133nMAssay Description:Covalent binding affinity to human Bcl2A1 by FBid based FP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511136(CHEMBL4558313)
Affinity DataKi:  150nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511125(CHEMBL4462138)
Affinity DataKi:  170nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50558855(CHEMBL4740212)
Affinity DataKi:  175nMAssay Description:Covalent binding affinity to human Bcl2A1 by FBid based FP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511139(CHEMBL4454113)
Affinity DataKi:  250nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511143(CHEMBL4463305)
Affinity DataKi:  280nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511122(CHEMBL4452560)
Affinity DataKi:  390nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM34194(3-chloranyl-1-(3,4-dichlorophenyl)-4-(4-methylpipe...)
Affinity DataKi:  400nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from His-tagged human BFL-1 (1 to 151 residues) expressed in Escherichia coli BL21 (DE3) assessed...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604885(CHEMBL5177177)
Affinity DataKi:  410nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50330250(5,5'-Dibenzyl-6,6',7,7'-tetrahydroxy-3,3'-dimethyl...)
Affinity DataKi:  430nMAssay Description:Displacement of F-BakBH3 from Bfl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50330257(6,6',7,7'-Tetrahydroxy-3,3'-dimethyl-5,5'-bis(2-ph...)
Affinity DataKi:  460nMAssay Description:Displacement of F-BakBH3 from Bfl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50330256(5,5'-Bis(4-chlorobenzyl)-6,6',7,7''-tetrahydroxy-3...)
Affinity DataKi:  470nMAssay Description:Displacement of F-BakBH3 from Bfl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50330258(6,6',7,7'-Tetrahydroxy-3,3'-dimethyl-1,1',4,4'-tet...)
Affinity DataKi:  470nMAssay Description:Displacement of F-BakBH3 from Bfl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511135(CHEMBL4457901)
Affinity DataKi:  570nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50078160(CHEMBL3417701)
Affinity DataKi: >660nMAssay Description:Inhibition of BCL2-A1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511138(CHEMBL4576854)
Affinity DataKi:  680nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511137(CHEMBL4475729)
Affinity DataKi:  760nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511134(CHEMBL4435041)
Affinity DataKi:  810nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50330251(CHEMBL1269012 | N5,N5'-Bis(4-ethylphenethyl)-6,6',...)
Affinity DataKi:  870nMAssay Description:Displacement of F-BakBH3 from Bfl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511144(CHEMBL4440719)
Affinity DataKi:  900nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50330248(6,6',7,7'-Tetrahydroxy-5,5'-diisobutyl-3,3'-dimeth...)
Affinity DataKi:  930nMAssay Description:Displacement of F-BakBH3 from Bfl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511146(CHEMBL4473975)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of BH3 peptide binding to human recombinant A1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511126(CHEMBL4525910)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50013865(CHEMBL3265297)
Affinity DataKi:  1.11E+3nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged A1-BFL-1 (1 to 151) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604880(CHEMBL5191993)
Affinity DataKi:  1.13E+3nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50330247(6,6',7,7'-Tetrahydroxy-5,5'-diisopropyl-3,3'-dimet...)
Affinity DataKi:  1.47E+3nMAssay Description:Displacement of F-BakBH3 from Bfl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511128(CHEMBL4448621)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511145(CHEMBL4577267)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50013862(CHEMBL3265294)
Affinity DataKi:  2.34E+3nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged A1-BFL-1 (1 to 151) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604882(CHEMBL5200494)
Affinity DataKi:  2.41E+3nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604879(CHEMBL5187810)
Affinity DataKi:  2.85E+3nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604877(CHEMBL5189912)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from His-tagged human BFL-1 (1 to 151 residues) expressed in Escherichia coli BL21 (DE3) assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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